Professor David Ziegler

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Prof David Ziegler is a Senior Staff Specialist in the Kids Cancer Centre at Sydney Children’s Hospital and has expertise in neuro-oncology and early phase clinical trials.�� Prof Ziegler completed his clinical training in paediatric haematology and oncology at Sydney Children’s Hospital and as a Fulbright Scholar at the Dana Farber Cancer Institute, Harvard Medical School and Children’s Hospital Boston.�� He is a Conjoint Professor at the University of New South Wales and a Group Leader at the Children’s Cancer Institute (CCI), where his preclinical research focuses on novel therapies for childhood brain tumours. He leads the neuro-oncology and clinical trials programs at the Kids Cancer Centre, Sydney Children's Hospital. He is Director of the Kids Cancer Alliance – a translational research program developed with the support of the Cancer Institute NSW.
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Phone

+61-2-93821730

Journal articles | 2024

Chen Y; Khan A; Katsinas C; Michniewicz F; Goldberg J; Franshaw L; Tsoli M; Ziegler DS, 2024, 'Preclinical evaluation of protein synthesis inhibitor omacetaxine in pediatric brainstem gliomas', Neuro-Oncology Advances, 6,

Journal articles | 2024

Das A; Fernandez NR; Levine A; Bianchi V; Stengs LK; Chung J; Negm L; Dimayacyac JR; Chang Y; Nobre L; Ercan AB; Sanchez-Ramirez S; Sudhaman S; Edwards M; Larouche V; Samuel D; Van Damme A; Gass D; Ziegler DS; Bielack SS; Koschmann C; Zelcer S; Yalon-Oren M; Campino GA; Sarosiek T; Nichols KE; Loret De Mola R; Bielamowicz K; Sabel M; Frojd CA; Wood MD; Glover JM; Lee YY; Vanan M; Adamski JK; Perreault S; Chamdine O; Hjort MA; Zapotocky M; Carceller F; Wright E; Fedorakova I; Lossos A; Tanaka R; Osborn M; Blumenthal DT; Aronson M; Bartels U; Huang A; Ramaswamy V; Malkin D; Shlien A; Villani A; Dirks PB; Pugh TJ; Getz G; Maruvka YE; Tsang DS; Ertl-Wagner B; Hawkins C; Bouffet E; Morgenstern DA; Tabori U, 2024, 'Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium', Cancer Discovery, 14, pp. 259 - 273,

Journal articles | 2024

Desai K; Rosenberg T; Power P; Manoharan N; Nagabushan S; Green-Murphy A; Ziegler DS; Li Y; Fisher MJ; Chi S, 2024, 'ATRT-11. IRS-III: LONG-TERM FOLLOW-UP SHOWS FAVORABLE OUTCOMES AND DURABLE RESPONSES FOR LOCALIZED ATYPICAL TERATOID RHABDOID TUMOR (ATRT)', Neuro-Oncology, 26,

Journal articles | 2024

Duchatel RJ; Jackson ER; Parackal SG; Kiltschewskij D; Findlay IJ; Mannan A; Staudt DE; Thomas BC; Germon ZP; Laternser S; Kearney PS; Jamaluddin MFB; Douglas AM; Beitaki T; McEwen HP; Persson ML; Hocke EA; Jain V; Aksu M; Manning EE; Murray HC; Verrills NM; Sun CX; Daniel P; Vilain RE; Skerrett-Byrne DA; Nixon B; Hua S; de Bock CE; Colino-Sanguino Y; Valdes-Mora F; Tsoli M; Ziegler DS; Cairns MJ; Raabe EH; Vitanza NA; Hulleman E; Phoenix TN; Koschmann C; Alvaro F; Dayas CV; Tinkle CL; Wheeler H; Whittle JR; Eisenstat DD; Firestein R; Mueller S; Valvi S; Hansford JR; Ashley DM; Gregory SG; Kilburn LB; Nazarian J; Cain JE; Dun MD; Valdes Mora F, 2024, 'PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma', Journal of Clinical Investigation, 134, pp. e170329,

Journal articles | 2024

Ercan AB; Aronson M; Fernandez NR; Chang Y; Levine A; Liu ZA; Negm L; Edwards M; Bianchi V; Stengs L; Chung J; Al-Battashi A; Reschke A; Lion A; Ahmad A; Lassaletta A; Reddy AT; Al-Darraji AF; Shah AC; Van Damme A; Bendel A; Rashid A; Margol AS; Kelly BL; Pencheva B; Heald B; Lemieux-Anglin B; Crooks B; Koschmann C; Gilpin C; Porter CC; Gass D; Samuel D; Ziegler DS; Blumenthal DT; Kuo DJ; Hamideh D; Basel D; Khuong-Quang DA; Stearns D; Opocher E; Carceller F; Baris Feldman H; Toledano H; Winer I; Scheers I; Fedorakova I; Su JM; Vengoechea J; Sterba J; Knipstein J; Hansford JR; Gonzales-Santos JR; Bhatia K; Bielamowicz KJ; Minhas K; Nichols KE; Cole KA; Penney L; Hjort MA; Sabel M; Gil-da-Costa MJ; Murray MJ; Miller M; Blundell ML; Massimino M; Al-Hussaini M; Al-Jadiry MF; Comito MA; Osborn M; Link MP; Zapotocky M; Ghalibafian M; Shaheen N; Mushtaq N; Waespe N; Hijiya N; Fuentes-Bolanos N; Ahmad O; Chamdine O; Roy P; Pichurin PN; Nyman P; Pearlman R; Auer RC; Sukumaran RK; Kebudi R; Dvir R; Raphael R; Elhasid R; McGee RB; Chami R; Noss R; Tanaka R; Raskin S; Sen S; Lindhorst S; Perreault S; Caspi S; Riaz S, 2024, 'Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study', The Lancet Oncology, 25, pp. 668 - 682,

Journal articles | 2024

Evans L; Walker R; MacDiarmid J; Brahmbhatt H; Anazodo A; McCowage G; Gifford AJ; Kavallaris M; Trahair T; Ziegler DS, 2024, 'A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor', Targeted Oncology, 19, pp. 333 - 342,

Journal articles | 2024

Haeusler GM; Dashti SG; James F; Babl FE; Borland ML; Clark JE; Padhye B; Tapp H; Alvaro F; Raj TS; Walwyn T; Ziegler DS; Super L; Hall L; Yeoh DK; Butters C; McMullan B; Hanna DMT; De Abreu Lourenco R; Slavin MA; Phillips B; Thursky KA, 2024, 'Impact of time to antibiotics on clinical outcome in paediatric febrile neutropenia: a target trial emulation of 1685 episodes', The Lancet Regional Health - Western Pacific, 53,

Journal articles | 2024

Hansford J; Valvi S; de Boer J; McCowage G; Govender D; Kirby M; Ziegler D; Manoharan N; Hassall T; Wainwright B; Alvaro F; Wood PJ; Eisenstat D; Quang DAK; Jenkins M; Dun M; Laughton SJ; Endersby R; Dodgshun A; Gottardo N, 2024, '“If you build it, they will come”: the convergence of funding, research and collaboration in paediatric brain cancer clinical trials', Medical Journal of Australia,

Journal articles | 2024

Hansford JR; Bouche G; Ramaswamy V; Jabado N; Fonseca A; Moloney S; Gottardo NG; Robinson GW; Gajjar A; Tinkle CL; Fisher PG; Foreman N; Ashley DM; Ziegler DS; Eisenstat DD; Massimino M; Witt O; Bartels U; Rutkowski S; Hargrave D; Fouladi M; Pfister SM; Bouffet E, 2024, 'Comments and Controversies in Oncology: The Tribulations of Trials Developing ONC201.', J Clin Oncol, pp. JCO2400709,

Journal articles | 2024

Hayden E; Dolman EM; Upton DH; Franshaw L; Liu J; Nguyen H; Tsoli M; Guo X; Mayoh C; Rayner BS; Ziegler DS, 2024, 'DIPG-50. TARGETING VULNERABILITIES IN PAEDIATRIC DIFFUSE MIDLINE GLIOMAS: LEVERAGING PLK1 INHIBITION TO EXPLOIT RAS/PI3K PATHWAY DEPENDENCY', Neuro-Oncology, 26,

Journal articles | 2024

Hetherington K; Wakefield CE; McGill BC; Tucker KM; Donoghoe MW; Daly R; Hunter JD; Ballinger M; Fuentes-Bolanos NA; Ziegler DS, 2024, 'When genetics and pediatric cancer collide: Understanding and optimizing families' experiences', Neuro-Oncology Advances, 6,

Journal articles | 2024

Hogarty MD; Ziegler DS; Franson A; Chi YY; Tsao-Wei D; Liu K; Vemu R; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer B; Balis FM; Groshen S; Norris MD; Haber M; Park JR; Matthay KK; Marachelian A, 2024, 'Phase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial', British Journal of Cancer, 130, pp. 788 - 797,

Journal articles | 2024

Holliday H; Khan A; Jayatilleke N; Mayoh C; Ross SE; Guo X; Sanguino YC; Gopalakrishnan A; Ehteda A; Tsoli M; Ziegler DS, 2024, 'DIPG-24. COMBINED EPIGENETIC THERAPY WITH FACT AND BET INHIBITORS REMODELS CHROMATIN AND DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA', Neuro-Oncology, 26,

Journal articles | 2024

Holliday H; Khan A; Jayatilleke N; Mayoh C; Ross SE; Sanguino YC; Gopalakrishnan A; Ehteda A; Rayner B; Tsoli M; Ziegler DS, 2024, 'Abstract B016: Targeting the epigenome through combined Facilitates Chromatin Transcription (FACT) and Bromodomain and Extra-Terminal Domain (BET) inhibition in Diffuse Midline Glioma (DMG)', Cancer Research, 84, pp. B016 - B016,

Journal articles | 2024

Jessop SJ; Fuentos-Bolanos N; Mayoh C; Dolman MEM; Tax G; Wong-Erasmus M; Ajuyah P; Tyrell V; Marshall GM; Ziegler DS; Lau LMS, 2024, 'High throughput screening aids clinical decision-making in refractory acute myeloid leukaemia', Cancer Reports, 7,

Journal articles | 2024

Jose J; Choi P; Tsoli M; Gopalakrishnan A; Lee C; Park TII; Ziegler D; Denny W, 2024, 'AB005. Development of tumour specific therapy for treatment of diffuse intrinsic pontine glioma (DIPG)', Chinese clinical oncology, 13, pp. AB005,

Journal articles | 2024

Kelada L; Robertson EG; McKay S; McGill BC; Daly R; Mazariego C; Taylor N; Tyedmers E; Armitage N; Evans HE; Wakefield CE; Ziegler DS, 2024, 'Communicating with families of young people with hard-to-treat cancers: Healthcare professionals’ perspectives on challenges, skills, and training', Palliative and Supportive Care, 22, pp. 539 - 545,

Journal articles | 2024

Kerras S; Hetherington K; Toofanian S; Manoharan N; Ziegler DS; Mateos MK, 2024, 'Second Opinion Seeking in Paediatric Oncology: Motivations and Predictors', Psycho-Oncology, 33,

Journal articles | 2024

Khan A; Gopalakrishnan A; Liu J; Burns MR; Tsoli M; Ziegler DS, 2024, 'Abstract B047: Inhibition of the polyamine pathway: a novel therapeutic approach to treat aggressive pediatric medulloblastoma', Cancer Research, 84, pp. B047 - B047,

Journal articles | 2024

Khan A; Gopalakrishnan A; Liu J; Burns MR; Tsoli M; Ziegler DS, 2024, 'MDB-61. STARVING TUMORS OF POLYAMINES: A NOVEL APPROACH IN TREATING AGGRESSIVE PEDIATRIC MEDULLOBLASTOMA', Neuro-Oncology, 26,

Journal articles | 2024

Khan A; Upton D; Gopalakrishnan A; Chen Y; Tsoli M; Ziegler DS, 2024, 'DIPG-46. TOTAL THERAPY FOR DIFFUSE MIDLINE GLIOMAS: A SEQUENTIAL, INTENSIVE, MULTI-AGENT COMBINATION PLATFORM IS A POTENT TREATMENT STRATEGY', Neuro-Oncology, 26,

Journal articles | 2024

Kilburn LB; Khuong-Quang DA; Hansford JR; Landi D; van der Lugt J; Leary SES; Driever PH; Bailey S; Perreault S; McCowage G; Waanders AJ; Ziegler DS; Witt O; Baxter PA; Kang HJ; Hassall TE; Han JW; Hargrave D; Franson AT; Yalon Oren M; Toledano H; Larouche V; Kline C; Abdelbaki MS; Jabado N; Gottardo NG; Gerber NU; Whipple NS; Segal D; Chi SN; Oren L; Tan EEK; Mueller S; Cornelio I; McLeod L; Zhao X; Walter A; Da Costa D; Manley P; Blackman SC; Packer RJ; Nysom K, 2024, 'Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial, (Nature Medicine, (2023), 10.1038/s41591-023-02668-y)', Nature Medicine, 30, pp. 1500,

Journal articles | 2024

Kilburn LB; Khuong-Quang DA; Hansford JR; Landi D; van der Lugt J; Leary SES; Driever PH; Bailey S; Perreault S; McCowage G; Waanders AJ; Ziegler DS; Witt O; Baxter PA; Kang HJ; Hassall TE; Han JW; Hargrave D; Franson AT; Yalon Oren M; Toledano H; Larouche V; Kline C; Abdelbaki MS; Jabado N; Gottardo NG; Gerber NU; Whipple NS; Segal D; Chi SN; Oren L; Tan EEK; Mueller S; Cornelio I; McLeod L; Zhao X; Walter A; Da Costa D; Manley P; Blackman SC; Packer RJ; Nysom K, 2024, 'The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial', Nature Medicine, 30, pp. 207 - 217,

Journal articles | 2024

Kline C; Waanders AJ; Ziegler DS; Kilburn LB; Nysom K; van der Lugt J; Hassall TE; Gerber NU; Segal D; Larouche V; Khuong-Quang D-A; Hansford JR; Leary SES; Driever PH; Bailey S; Perreault S; McCowage G; Witt O; Baxter PA; Kang HJ; Han JW; Hargrave D; Franson AT; Oren MY; Toledano H; Abdelbaki MS; Jabado N; Gottardo NG; Whipple NS; Chi SN; Oren L; Tan EEK; Mueller S; Wright KD; Blackman SC; Qiu J; Podesta D; Walter A; Da Costa D; Manley P; McLeod L; Landi DB, 2024, 'LGG-40. TYPE II RAF INHIBITOR TOVORAFENIB IN RELAPSED/REFRACTORY PEDIATRIC LOW-GRADE GLIOMA (PLGG): REVERSIBLE DECREASES IN GROWTH VELOCITY IN THE PHASE 2 FIREFLY-1 TRIAL', Neuro-Oncology, 26,

Journal articles | 2024

Kline C; Waanders AJ; Ziegler DS; Kilburn LB; Nysom K; van der Lugt J; Hassall TE; Gerber NU; Segal D; Larouche V; Mueller S; Walter A; Manley P; McLeod L; Landi DB, 2024, 'Type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma (pLGG): Reversible decreases in growth velocity in the phase 2 FIREFLY-1 trial.', Journal of Clinical Oncology, 42, pp. 10036 - 10036,

Journal articles | 2024

Lamoureux A-A; Fisher MJ; Lemelle L; Pfaff E; Amir-Yazdani P; Kramm C; De Wilde B; Kazanowska B; Hutter C; Pfister SM; Sturm D; Jones DTW; Orbach D; Pierron G; Raskin S; Drilon A; Diamond EL; Harada G; Zapotocky M; Zamecnik J; Krskova L; Ellezam B; Weil AG; Venne D; Barritault M; Leblond P; Coltin H; Hammad R; Tabori U; Hawkins C; Hansford JR; Meyran D; Erker C; McFadden K; Sato M; Gottardo NG; Dholaria H; Nørøxe DS; Goto H; Ziegler DS; Lin FY; Parsons DW; Lindsay H; Wong T-T; Liu Y-L; Wu K-S; Franson AT; Hwang E; Aguilar-Bonilla A; Cheng S; Cacciotti C; Massimino M; Schiavello E; Wood P; Hoffman LM; Cappellano A; Lassaletta A; Van Damme A; Llort A; Gerber NU; Spalato Ceruso M; Bendel AE; Skrypek M; Hamideh D; Mushtaq N; Walter A; Jabado N; Alsahlawi A; Farmer J-P; Coleman C; Mueller S; Mazewski C; Aguilera D; Robison NJ; O'Halloran K; Abbou S; Berlanga P; Geoerger B; Øra I; Moertel CL; Razis ED; Vernadou A; Ducray F; Bronnimann C; Seizeur R; Clarke M; Resnick AC; Alves M; Jones C; Doz F; Laetsch TW; Perreault S, 2024, 'Clinical characteristics and outcome of central nervous system tumors harboring NTRK gene fusions.', Clin Cancer Res,

Journal articles | 2024

Lau L; Khoung-Quang DA; Chelsea M; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester AK; Fuentes-Bolanos N; Sullivan A; Mateos M; Tyrrell N; Haber M; Trahair T; Cowley M; Marshall G; Ekert P; Ziegler D, 2024, '438 (PB426): Precision-guided treatment improves outcomes for children with highrisk cancers', European Journal of Cancer, 211, pp. 114946 - 114946,

Journal articles | 2024

Lau LMS; Khuong-Quang D-A; Staunton J; Sanders N; Sriharan S; Trinder S; Manoharan N; Barahona P; Altekoester A-K; Dias K; Rumford M; Sylvester D; Parhar J; Mateos MK; Wong M; Mayoh C; Cowley MJ; Ekert PG; Haber M; Tyrrell V; Ziegler DS, 2024, 'Abstract B012: Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors', Cancer Research, 84, pp. B012 - B012,

Journal articles | 2024

Lau LMS; Khuong-Quang DA; Mayoh C; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester AK; Fuentes-Bolanos NA; Yeung V; Sullivan A; Omer N; Diamond Y; Jessop S; Battaglia L; Zhukova N; Cui L; Lin A; Gifford AJ; Fleuren EDG; Dalla-Pozza L; Moore AS; Khaw SL; Eisenstat DD; Gottardo NG; Wood PJ; Tapp H; Alvaro F; McCowage G; Nicholls W; Hansford JR; Manoharan N; Kotecha RS; Mateos MK; Lock RB; Tyrrell V; Haber M; Trahair TN; Cowley MJ; Ekert PG; Marshall GM; Ziegler DS, 2024, 'Precision-guided treatment in high-risk pediatric cancers', Nature Medicine, 30, pp. 1913 - 1922,

Journal articles | 2024

Manoharan N; Cooney T; DeWire-Schottmiller M; Lane A; Nellan A; Leary S; Partap S; Kilburn L; Wright KD; Hummel T; Ziegler DS; Fouladi M; Hoffman LM; Warren KE, 2024, 'DIPG-52. CEREBROSPINAL FLUID DIVERSION DOES NOT PROLONG OVERALL SURVIVAL IN CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, 26,

Journal articles | 2024

Mateos MK; Ajuyah P; Fuentes-Bolanos N; Kamand SE; Barahona P; Altekoester A; Mayoh C; Holiday H; Liu J; Cui L; Pfaff E; Mackay A; Resnick A; Pinese M; Lau LMS; Khuong-Quang D-A; Dias K; Goudie C; Salkeld A; Rokita JL; Jones DTW; Juretic N; Hayden E; Pfister SM; Kramm CM; Blattner-Johnson M; Jabado N; Tsoli M; Vittorio O; Mueller S; Guo Y; Tucker K; Waszak SM; Perreault S; Jones C; Wong-Erasmus M; Cowley MJ; Ziegler DS, 2024, 'DIPG-76. PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA DEMONSTRATE AN UNEXPECTED PREVALENCE OF GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION GENES', Neuro-Oncology, 26,

Journal articles | 2024

Mazariego C; Daly R; McGill B; Kelada L; McKay S; Hetherington K; Ziegler DS; Wakefield CE; Taylor N, 2024, 'Barriers to access of precision guided therapies for children with high-risk cancer', Pediatric Blood and Cancer, 71,

Journal articles | 2024

Mazariego CG; McKay S; Tyedmers E; Kelada L; McGill BC; Daly R; Wakefield CE; Ziegler DS; Taylor N; Mazariego-Jones C, 2024, 'Co-design of a paediatric oncology medicines database (ProCure) to support complex care provision for children with a hard-to-treat cancer', Frontiers in Medicine, 11, pp. 1332434,

Journal articles | 2024

Nagabushan S; Fuentes-Bolanos N; Lau LMS; Rumford M; Warby M; Courtney E; Grant A; Rodriguez M; Solinas A; Ziegler DS; Kellie SJ; Heath J; Ballinger M; Tucker K, 2024, 'HGG-50. LOW GRADE GLIOMA CAUGHT IN TRANSFORMATION: UTILITY OF COMPREHENSIVE GENOMIC PROFILING IN PEDIATRIC LI FRAUMENI SYNDROME ASSOCIATED HIGH-GRADE GLIOMA', Neuro-Oncology, 26,

Journal articles | 2024

Peipert JD; Baxter PA; Yu S; Oestreicher N; Zelt S; Driever PH; Bailey S; McCowage G; Ziegler DS; Witt O; Kang HJ; Hassall TE; Han JW; Franson AT; Oren MY; Toledano H; Larouche V; Abdelbaki MS; Jabado N; Gottardo NG; Gerber NU; Whipple NS; Segal D; Chi SN; Oren L; Tan EEK; Mueller S; Kilburn LB; Nysom K; Khuong-Quang D-A; Landi DB; van der Lugt J; Leary SES; Perreault S; Waanders AJ; Hargrave D; Kline C; McKenna C; Manley P; Raju SG; Hansford JR, 2024, 'NCOG-05. HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN THE PHASE 2 FIREFLY-1 (PNOC026) TRIAL OF THE TYPE II RAF INHIBITOR TOVORAFENIB IN RELAPSED/REFRACTORY (R/R) PEDIATRIC LOW-GRADE GLIOMA (PLGG)', Neuro-Oncology, 26, pp. viii224 - viii225,

Journal articles | 2024

Perreault S; Khuong-Quang D-A; Kilburn LB; Landi DB; Leary SES; Bailey S; Larouche V; Nysom K; Driever PH; Baxter PA; Witt O; Oren MY; Abdelbaki MS; Kline C; Whipple NS; Ziegler DS; van der Lugt J; Hassall TE; Gerber NU; Segal D; Hansford JR; McCowage G; Kang HJ; Han JW; Hargrave D; Franson AT; Toledano H; Jabado N; Gottardo NG; Chi SN; Oren L; Tan EEK; Mueller S; Hoke ME; Kim Y; Walter A; Da Costa D; Manley P; Waanders AJ, 2024, 'CTNI-09. TYPE II RAF INHIBITOR TOVORAFENIB IN RELAPSED/REFRACTORY (R/R) PEDIATRIC LOW-GRADE GLIOMA (PLGG): RESULTS FROM PATIENTS ON A DRUG HOLIDAY (DH) IN THE PHASE 2 FIREFLY-1 TRIAL', Neuro-Oncology, 26, pp. viii96 - viii97,

Journal articles | 2024

Rayner BS; Samadder A; Holliday H; Chen Y; Nguyen H; Lee A; Liu J; Hayden E; Ogunmodede OS; Rye K-A; Tsoli M; Bertoldo JB; Ziegler DS, 2024, 'DIPG-16. THE BIG AND SMALL OF PROTEIN POST-TRANSLATIONAL MODIFICATIONS: TARGETING SUMOYLATION AND CITRULLINATION IN DIFFUSE MIDLINE GLIOMA', Neuro-Oncology, 26,

Journal articles | 2024

Revon-Rivière G; Hetherington K; Siddiqi A; Wong L; Mitchell LG; Connolly D; Morgenstern D; Ziegler DS; Cohen-Gogo S, 2024, 'Abstract B066: Bridging patient reported outcomes and CTCAE to improve supportive care and trial design: The PROptimise initiative', Cancer Research, 84, pp. B066 - B066,

Journal articles | 2024

Robertson EG; Hetherington K; Daly R; Donoghoe MW; Handelsman N; Ziegler DS; Wakefield CE, 2024, 'The feasibility and acceptability of collecting psychosocial outcome measures embedded within a precision medicine trial for childhood cancer', Cancer Medicine, 13,

Journal articles | 2024

Ross SE; Holliday H; Tsoli M; Ziegler DS; Dinger ME, 2024, 'Abstract B015: RNA N6-methyladenosine (m6A) as a therapeutic target in Diffuse Midline Glioma (DMG)', Cancer Research, 84, pp. B015 - B015,

Journal articles | 2024

Salomon R; Chen W; Shale C; Toumari M; Lowe A; Li W; Chen J; Bazaz SR; Barahona P; Cui L; Mayoh C; El-Kamand S; Tryell V; Wong-Erasmus M; Lau LMS; Bolanos NF; Cuppen E; Khuong Quang DA; Staunton J; Mateos MK; Trahair T; Haber M; Ziegler DS; Ekert PG; Priestley P; Cowley MJ, 2024, 'Abstract A045 Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours', Cancer Research, 84, pp. A045 - A045,

Journal articles | 2024

Salomon R; Li W; Toumari M; Lowe A; Mayoh C; Barahona P; Lau LMS; Staunton J; Jacobson E; Nagabushan S; Manoharan N; Mitchell R; Ong F; Haber M; Ziegler DS; Cowley MJ; Mateos MK, 2024, 'Abstract A044 Enhanced disease detection using single cell RNAseq in children with brain cancer', Cancer Research, 84, pp. A044 - A044,

Journal articles | 2024

Staunton J; Ajuyah P; Harris A; Mayoh C; Wong M; Rumford M; Sullivan PJ; Ekert PG; Fuentes-Bolanos N; Cowley MJ; Lau LMS; Ziegler DS; Barahona P; Manoharan N, 2024, 'Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome', npj Precision Oncology, 8,

Journal articles | 2024

Tax G; Mao J; Cadiz R; Barhen T; Xie J; Harris J; Bae M; Brown LM; Pazaky K; Gifford AJ; Mayoh C; Mateos MK; Peterziel H; Oehme I; Ziegler DS; Tsoli M; Rayner B; Ekert PG; Dolman MEM, 2024, 'Abstract B003: Expanding therapeutic horizons: Unleashing the untapped potential of MEK inhibitor treatment in pediatric cancers', Cancer Research, 84, pp. B003 - B003,

Journal articles | 2024

Tsoli M; Ung C; Upton DH; Venkat P; Salerno A; Pandher R; Mayoh C; Vittorio O; Ziegler DS, 2024, 'DIPG-35. OVERCOMING THE BLOOD-BRAIN BARRIER CHALLENGE IN DIFFUSE MIDLINE GLIOMA', Neuro-Oncology, 26,

Journal articles | 2024

Upton DH; Ziegler DS; Tsoli M, 2024, 'Development of Orthotopic Patient-Derived Xenograft Models of Pediatric Intracranial Tumors', , 2806, pp. 75 - 90,

Journal articles | 2024

Valvi S; Manoharan N; Mateos MK; Hassall TEG; Ziegler DS; McCowage GB; Dun MD; Eisenstat DD; Gottardo NG; Hansford JR, 2024, 'Management of patients with diffuse intrinsic pontine glioma in Australia and New Zealand: Australian and New Zealand Children's Haematology/Oncology Group position statement', Medical Journal of Australia, 220, pp. 533 - 538,

Journal articles | 2024

Wang YZM; Kaj-Carbaidwala B; Lane A; Agarwal S; Beier F; Bertuch A; Borovsky KA; Brennan SK; Calado RT; Catto LFB; Dufour C; Ebens CL; Fioredda F; Giri N; Gloude N; Goldman F; Hertel PM; Himes R; Keel SB; Koura DT; Kratz CP; Kulkarni S; Liou I; Nakano TA; Nastasio S; Niewisch MR; Penrice DD; Sasa GS; Savage SA; Simonetto DA; Ziegler DS; Miethke AG; Myers KC, 2024, 'Liver disease and transplantation in telomere biology disorders: An international multicenter cohort', Hepatology Communications, 8, pp. e0462,

Journal articles | 2024

Ziegler DS; Hassall T; Valvi S; Cai D, 2024, 'DIPG-84. PHASE 1 DOSE-ESCALATION STUDY OF ACT001 IN PEDIATRIC PATIENTS WITH ADVANCED BRAIN AND SOLID TUMORS SHOWS ACTIVITY IN DIFFUSE MIDLINE GLIOMA (DMG)', Neuro-Oncology, 26,

Journal articles | 2024

Ziegler DS; Lehmann R; Eisenstat DD, 2024, 'A paradigm shift in how we treat pediatric low-grade glioma—Targeting the molecular drivers', Neuro-Oncology, 26, pp. 593 - 595,

Journal articles | 2024

van Tilburg CM; Kilburn LB; Perreault S; Schmidt R; Azizi AA; Cruz-Martínez O; Zápotocký M; Scheinemann K; Meeteren AYNSV; Sehested A; Opocher E; Driever PH; Avula S; Ziegler DS; Capper D; Koch A; Sahm F; Qiu J; Tsao LP; Blackman SC; Manley P; Milde T; Witt R; Jones DTW; Hargrave D; Witt O, 2024, 'LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration', BMC Cancer, 24,

Journal articles | 2023

Ajuyah P; Mayoh C; Lau LMS; Barahona P; Wong M; Chambers H; Valdes-Mora F; Senapati A; Gifford AJ; D’Arcy C; Hansford JR; Manoharan N; Nicholls W; Williams MM; Wood PJ; Cowley MJ; Tyrrell V; Haber M; Ekert PG; Ziegler DS; Khuong-Quang DA; Valdes Mora F, 2023, 'Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes', Scientific Reports, 13, pp. 3775,

Journal articles | 2023

Daly R; Hetherington K; Hazell E; Wadling BR; Tyrrell V; Tucker KM; Marshall GM; Ziegler DS; Lau LMS; Trahair TN; O’Brien TA; Collins K; Gifford AJ; Haber M; Pinese M; Malkin D; Cowley MJ; Karpelowsky J; Drew D; Jacobs C; Wakefield CE, 2023, 'Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 13,

Journal articles | 2023

Daniel P; Sun CX; Bradshaw G; Shi H; Loi M; Chew N; Parackal S; Tsui V; Liang Y; Koptyra M; Adjumain S; Sun C; Chong WC; Fernando D; Drinkwater C; Tourchi M; Habarakada D; Carvalho D; Storm PB; Baubet V; Sayles LC; Fernandez E; Zhukova N; Dun MD; Ludlow LE; Day B; Stringer BW; Neeman N; Rubens JA; Raabe EH; Vinci M; Tyrrell V; Fletcher JI; Ekert PG; Dumevska B; Ziegler DS; Tsoli M; Sulaiman NFS; Loh AHP; Low SYY; Sweet-Cordero EA; Monje M; Resnick A; Jones C; Downie P; Williams B; Rosenbluh J; Gough D; Cain JE; Firestein R, 2023, 'SYST-15 GENERATION AND MULTI-DIMENSIONAL PROFILING OF A CHILDHOOD CANCER CELL LINE ATLAS DEFINES NEW THERAPEUTIC OPPORTUNITIES', Neuro-Oncology Advances, 5, pp. iii30 - iii30,

Journal articles | 2023

Ehteda A; Khan A; Rajakumar G; Vanniasinghe AS; Gopalakrishnan A; Liu J; Tsoli M; Ziegler DS, 2023, 'Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas', Molecular Cancer Therapeutics, 22, pp. 1413 - 1421,

Journal articles | 2023

Geoerger B; Marshall LV; Nysom K; Makin G; Bouffet E; Defachelles AS; Amoroso L; Aerts I; Leblond P; Barahona P; Van-Vlerken K; Fu E; Solca F; Lorence RM; Ziegler DS, 2023, 'Afatinib in paediatric patients with recurrent/refractory ErbB-dysregulated tumours: Results of a phase I/expansion trial', European Journal of Cancer, 188, pp. 8 - 19,

Journal articles | 2023

Gereis JM; Hetherington K; Robertson EG; Daly R; Donoghoe MW; Ziegler DS; Marshall GM; Lau LMS; Marron JM; Wakefield CE, 2023, 'Parents’ and adolescents’ perspectives and understanding of information about childhood cancer precision medicine', Cancer, 129, pp. 3645 - 3655,

Journal articles | 2023

Gonzales-Aloy E; Ahmed-Cox A; Tsoli M; Ziegler DS; Kavallaris M, 2023, 'From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer', Advanced Drug Delivery Reviews, 196,

Journal articles | 2023

Grebstad Tune B; Sareen H; Powter B; Kahana-Edwin S; Cooper A; Koh ES; Lee CS; Po JW; McCowage G; Dexter M; Cain L; O’Neill G; Prior V; Karpelowsky J; Tsoli M; Baumbusch LO; Ziegler D; Roberts TL; DeSouza P; Becker TM; Ma Y, 2023, 'From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients', Biomedicines, 11,

Journal articles | 2023

Hardin EC; Schmid S; Sommerkamp A; Bodden C; Heipertz AE; Sievers P; Wittmann A; Milde T; Pfister SM; von Deimling A; Horn S; Herz NA; Simon M; Perera AA; Azizi A; Cruz O; Curry S; Van Damme A; Garami M; Hargrave D; Kattamis A; Kotnik BF; Lähteenmäki P; Scheinemann K; Schouten-Van Meeteren AYN; Sehested A; Viscardi E; Wormdal OM; Zapotocky M; Ziegler DS; Koch A; Driever PH; Witt O; Capper D; Sahm F; Jones DTW; van Tilburg CM, 2023, 'LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients', Neuro-Oncology, 25, pp. 2087 - 2097,

Journal articles | 2023

Hayden E; Franshaw L; Upton D; Liu J; Nguyen H; Joshi S; Tsoli M; Dolman E; Rayner B; Ziegler D, 2023, 'Abstract 1561: Preclinical examination of PLK1 inhibitors for the treatment of diffuse midline gliomas', Cancer Research, 83, pp. 1561 - 1561,

Journal articles | 2023

Kilburn L; Khuong-Quang D-A; Nysom K; Landi D; Ziegler D; Driever PH; Leary S; Bailey S; Van der Lugt J; Perreault S; Waanders A; Baxter P; Witt O; Hargrave D; McCowage G; Zhao X; Da Costa D; Cox M; Manley P; Hansford J, 2023, 'LGG-09. CLINICAL ACTIVITY OF PAN-RAF INHIBITOR TOVORAFENIB IN THE REGISTRATIONAL PEDIATRIC LOW-GRADE GLIOMA ARM OF THE PHASE 2 FIREFLY-1 (PNOC026) STUDY', Neuro-Oncology, 25, pp. i57 - i57,

Journal articles | 2023

Kilburn LB; Khuong-Quang D-A; Nysom K; Landi DB; Ziegler DS; Hernáiz Driever P; Leary S; Bailey S; van der Lugt J; Perreault S; Waanders AJ; Baxter PA; Witt O; Hargrave DR; McCowage GB; Zhao X; Da Costa D; Cox MC; Manley P; Hansford J, 2023, 'Clinical activity of pan-RAF inhibitor tovorafenib in the registrational pediatric low-grade glioma arm of the phase 2 FIREFLY-1 (PNOC026) study.', Journal of Clinical Oncology, 41, pp. 10004 - 10004,

Journal articles | 2023

Kummar S; Shen L; Hong DS; McDermott R; Keedy VL; Casanova M; Demetri GD; Dowlati A; Melcón SG; Lassen UN; Leyvraz S; Liu T; Moreno V; Patel J; Patil T; Mallick AB; Sousa N; Tahara M; Ziegler DS; Norenberg R; Arvis P; Brega N; Drilon A; Tan DSW, 2023, 'Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas', Cancer, 129, pp. 3772 - 3782,

Journal articles | 2023

Lehmann R; Zhu J; Mayoh C; Tsoli M; Rayner B; Ziegler D, 2023, 'DDDR-30. IDENTIFICATION OF DRIVERS OF RESISTANCE IN BRAFV600E PEDIATRIC HIGH-GRADE GLIOMA AND NOVEL THERAPEUTIC TARGETS', Neuro-Oncology, 25, pp. v112 - v112,

Journal articles | 2023

Lilly JV; Rokita JL; Mason JL; Patton T; Stefankiewiz S; Higgins D; Trooskin G; Larouci CA; Arya K; Appert E; Heath AP; Zhu Y; Brown MA; Zhang B; Farrow BK; Robins S; Morgan AM; Nguyen TQ; Frenkel E; Lehmann K; Drake E; Sullivan C; Plisiewicz A; Coleman N; Patterson L; Koptyra M; Helili Z; Van Kuren N; Young N; Kim MC; Friedman C; Lubneuski A; Blackden C; Williams M; Baubet V; Tauhid L; Galanaugh J; Boucher K; Ijaz H; Cole KA; Choudhari N; Santi M; Moulder RW; Waller J; Rife W; Diskin SJ; Mateos M; Parsons DW; Pollack IF; Goldman S; Leary S; Caporalini C; Buccoliero AM; Scagnet M; Haussler D; Hanson D; Firestein R; Cain J; Phillips JJ; Gupta N; Mueller S; Grant G; Monje-Deisseroth M; Partap S; Greenfield JP; Hashizume R; Smith A; Zhu S; Johnston JM; Fangusaro JR; Miller M; Wood MD; Gardner S; Carter CL; Prolo LM; Pisapia J; Pehlivan K; Franson A; Niazi T; Rubin J; Abdelbaki M; Ziegler DS; Lindsay HB; Stucklin AG; Gerber N; Vaske OM; Quinsey C; Rood BR; Nazarian J; Raabe E; Jackson EM; Stapleton S; Lober RM; Kram DE; Koschmann C; Storm PB; Lulla RR; Prados M; Resnick AC; Waanders AJ, 2023, 'The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science', Neoplasia (United States), 35,

Journal articles | 2023

Mayoh C; Gifford AJ; Terry R; Lau LMS; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang DA; Qin V; Mateos MK; Meyran D; Miller KE; Yuksel A; Mould EVA; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw SL; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, 2023, 'A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer', Genome Medicine, 15,

Journal articles | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow SO; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; M Dolman ME; Wong-Erasmus M; Ajuyah P, 2023, 'High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer', Cancer Research, 83, pp. 2716 - 2732,

Journal articles | 2023

McGill BC; Wakefield CE; Tucker KM; Daly RA; Donoghoe MW; Vetsch J; Warby M; Fuentes-Bolanos NA; Barlow-Stewart K; Kirk J; Courtney E; O’Brien TA; Marshall GM; Pinese M; Cowley MJ; Tyrrell V; Deyell RJ; Ziegler DS; Hetherington K, 2023, 'Parents’ expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial', Cancer, 129, pp. 3620 - 3632,

Journal articles | 2023

Murray J; Pandher R; Xiao L; Somers K; Brand J; Mosmann E; Alfred S; Kusuma F; Kearns A; Park JR; Marshall LV; Gorrini C; Chesler L; Hogarty MD; Pearson ADJ; Burns M; Fletcher JI; Ziegler D; Norris MD; Haber M, 2023, 'Abstract B132: Addition of AMXT1501 (polyamine uptake inhibitor) plus DFMO (polyamine synthesis inhibitor) to standard-of-care chemotherapy/anti-GD2 antibody in the TH-MYCN mouse neuroblastoma model, enhances efficacy compared to addition of DFMO alone', Molecular Cancer Therapeutics, 22, pp. B132 - B132,

Journal articles | 2023

Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Neumann DP; Zheng Y; Rouaen JRC; Jue TR; Michniewicz FT; Schadel P; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Cazzoli R; Brettle M; Slapetova I; Kasherman M; Whan R; Souza-Fonseca-Guimaraes F; Vahdat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, 2023, 'Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer', Cell and Bioscience, 13,

Journal articles | 2023

Staunton J; Robertson PA; Harris A; Mayoh C; Wong M; Rumford M; Fuentes-Bolanos N; Cowley M; Lau L; Ziegler DS; Barahona P; Manoharan N, 2023, 'HGG-20. NOVEL PAEDIATRIC CASE OF A SPINAL HIGH-GRADE ASTROCYTOMA WITH PILOID FEATURES IN A PATIENT WITH NOONAN SYNDROME', Neuro-Oncology, 25, pp. i44 - i44,

Journal articles | 2023

Sun CX; Daniel P; Bradshaw G; Shi H; Loi M; Chew N; Parackal S; Tsui V; Liang Y; Koptyra M; Adjumain S; Sun C; Chong WC; Fernando D; Drinkwater C; Tourchi M; Habarakada D; Sooraj D; Carvalho D; Storm PB; Baubet V; Sayles LC; Fernandez E; Nguyen T; Pörksen M; Doan A; Crombie DE; Panday M; Zhukova N; Dun MD; Ludlow LE; Day B; Stringer BW; Neeman N; Rubens JA; Raabe EH; Vinci M; Tyrrell V; Fletcher JI; Ekert PG; Dumevska B; Ziegler DS; Tsoli M; Syed Sulaiman NF; Loh AHP; Low SYY; Sweet-Cordero EA; Monje M; Resnick A; Jones C; Downie P; Williams B; Rosenbluh J; Gough D; Cain JE; Firestein R, 2023, 'Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities', Cancer Cell, 41, pp. 660 - 677.e7,

Journal articles | 2023

Trinder SM; McKay C; Power P; Topp M; Chan B; Valvi S; McCowage G; Govender D; Kirby M; Ziegler DS; Manoharan N; Hassall T; Kellie S; Heath J; Alvaro F; Wood P; Laughton S; Tsui K; Dodgshun A; Eisenstat DD; Endersby R; Luen SJ; Koh ES; Sim HW; Kong B; Gottardo NG; Whittle JR; Khuong-Quang DA; Hansford JR, 2023, 'BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience', Frontiers in Oncology, 13,

Journal articles | 2023

Wakefield CE; Hetherington K; Robertson EG; Donoghoe MW; Hunter JD; Vetsch J; Marron JM; Tucker KM; Marshall GM; Broom A; Haber M; Tyrrell V; Malkin D; Lau L; Mateos MK; O’Brien TA; Ziegler DS, 2023, 'Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives', British Journal of Cancer, 129, pp. 1634 - 1644,

Journal articles | 2023

White CL; Kinross KM; Moore MK; Rasouli E; Strong R; Jones JM; Cain JE; Sturm D; Sahm F; Jones DTW; Pfister SM; Robertson T; D'Arcy C; Rodriguez ML; Dyke JM; Junckerstorff R; Bhuva DD; Davis MJ; Wood P; Hassall T; Ziegler DS; Kellie S; McCowage G; Alvaro F; Kirby M; Heath JA; Tsui K; Dodgshun A; Eisenstat DD; Khuong-Quang DA; Wall M; Algar EM; Gottardo NG; Hansford JR, 2023, 'Implementation of DNA Methylation Array Profiling in Pediatric Central Nervous System Tumors: The AIM BRAIN Project: An Australian and New Zealand Children's Haematology/Oncology Group Study', Journal of Molecular Diagnostics, 25, pp. 709 - 728,

Journal articles | 2023

Whitehouse JP; Hii H; Mayoh C; Wong M; Ajuyah P; Barahona P; Cui L; Dholaria H; White CL; Buntine MK; Byrne J; Rodrigues da Silva K; Howlett M; Girard EJ; Tsoli M; Ziegler DS; Dyke JM; Lee S; Ekert PG; Cowley MJ; Gottardo NG; Endersby R, 2023, 'In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma', Frontiers in Oncology, 13,

Journal articles | 2023

van Tilburg CM; Kilburn LB; Crotty E; Smith AA; Perreault S; Franson AF; Jabado N; Hoffman LM; Schmidt R; Schouten-van Meeteren AYN; Sehestedt A; Opocher E; Hernáiz Driever P; Avula S; Ziegler DS; Qiu J; Tsao L-P; Manley P; Hargrave DR; Witt O, 2023, 'LOGGIC/FIREFLY-2: A phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.', Journal of Clinical Oncology, 41, pp. TPS10067 - TPS10067,

Journal articles | 2022

Bartlett AL; Lane A; Chaney B; Escorza NY; Black K; Cochrane A; Minturn J; Bartels U; Warren K; Hansford J; Ziegler D; Diez B; Goldman S; Packer R; Kieran M; DeWire-Schottmiller M; Erker C; Monje-Deisseroth M; Wagner L; Koschmann C; Dorris K; Shih CS; Hassall T; Samson Y; Fisher P; Wang SS; Tsui K; Sevlever G; Zhu X; Dexheimer P; Asher A; Fuller C; Drissi R; Jones B; Leach J; Fouladi M, 2022, 'Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry', Neuro-Oncology, 24, pp. 2190 - 2199,

Journal articles | 2022

Burke MJ; Ziegler DS; Bautista F; Attarbaschi A; Gore L; Locatelli F; M. O'Brien M; Pauly M; Kormany WN; Tian S; Morris CL; Baruchel A, 2022, 'Phase 1b study of carfilzomib with induction chemotherapy in pediatric relapsed/refractory acute lymphoblastic leukemia', Pediatric Blood and Cancer, 69,

Journal articles | 2022

Daniel P; Sun C; Koptyra M; Drinkwater C; Chew N; Bradshaw G; Loi M; Shi C; Tourchi M; Parackal S; Chong WC; Fernando D; Adjumain S; Nguyen H; Habarakada D; Sooraj D; Crombie D; Zhukova N; Jones C; Rubens J; Raabe E; Vinci M; Dun M; Ludlow L; Nazarian J; Fletcher J; Ekert P; Ziegler D; Loh AHP; Low SYY; Monje M; Neeman N; Williams B; Resnick A; Gough D; Cain J; Firestein R, 2022, 'MODL-17. The Childhood Brain Cancer Cell Line Atlas: A Resource for Biomarker Identification and Therapeutic Development', Neuro-Oncology, 24, pp. i172 - i172,

Journal articles | 2022

Das A; Sudhaman S; Morgenstern D; Coblentz A; Chung J; Stone SC; Alsafwani N; Liu ZA; Karsaneh OAA; Soleimani S; Ladany H; Chen D; Zatzman M; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira Nahum LC; Ercan AB; Nabbi A; Constantini S; Dvir R; Yalon-Oren M; Campino GA; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; De Mola RL; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler DS; George B; Van Damme A; Hijiya N; Gass D; McGee RB; Mordechai O; Bowers DC; Laetsch TW; Lossos A; Blumenthal DT; Sarosiek T; Yen LY; Knipstein J; Bendel A; Hoffman LM; Luna-Fineman S; Zimmermann S; Scheers I; Nichols KE; Zapotocky M; Hansford JR; Maris JM; Dirks P; Taylor MD; Kulkarni AV; Shroff M; Tsang DS; Villani A; Xu W; Aronson M; Durno C; Shlien A; Malkin D; Getz G; Maruvka YE; Ohashi PS; Hawkins C; Pugh TJ; Bouffet E; Tabori U, 2022, 'Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency', Nature Medicine, 28, pp. 125 - 135,

Journal articles | 2022

Doz F; Van Tilburg CM; Geoerger B; Højgaard M; Øra I; Boni V; Capra M; Chisholm J; Chung HC; Dubois SG; Gallego-Melcon S; Gerber NU; Goto H; Grilley-Olson JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Nysom K; Thorwarth A; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2022, 'Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors', Neuro-Oncology, 24, pp. 997 - 1007,

Journal articles | 2022

Erker C; Lane A; Chaney B; Leary S; Minturn JE; Bartels U; Packer RJ; Dorris K; Gottardo NG; Warren KE; Broniscer A; Kieran MW; Zhu X; White P; Dexheimer PJ; Black K; Asher A; Dewire M; Hansford JR; Gururangan S; Nazarian J; Ziegler DS; Sandler E; Bartlett A; Goldman S; Shih CS; Hassall T; Dholaria H; Bandopadhayay P; Samson Y; Monje M; Fisher PG; Dodgshun A; Parkin S; Chintagumpala M; Tsui K; Gass D; Larouche V; Broxson E; Garcia Lombardi M; Wang SS; Ma J; Hawkins C; Hamideh D; Wagner L; Koschmann C; Fuller C; Drissi R; Jones BV; Leach J; Fouladi M, 2022, 'Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 141 - 152,

Journal articles | 2022

Gargett T; Ebert LM; Truong NTH; Kollis PM; Sedivakova K; Yu W; Yeo ECF; Wittwer NL; Gliddon BL; Tea MN; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler DS; Pitson SM; Brown MP, 2022, 'GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma', Journal for ImmunoTherapy of Cancer, 10,

Journal articles | 2022

Gereis J; Hetherington K; Ha L; Robertson EG; Ziegler DS; Barlow-Stewart K; Tucker KM; Marron JM; Wakefield CE, 2022, 'Parents’ understanding of genome and exome sequencing for pediatric health conditions: a systematic review', European Journal of Human Genetics, 30, pp. 1216 - 1225,

Journal articles | 2022

Hetherington K; Wakefield CE; Kunalan KPK; Donoghoe MW; McGill BC; Fardell JE; Daly R; Deyell RJ; Ziegler DS, 2022, 'Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer', Cancers, 14,

Journal articles | 2022

Hunter JD; Robertson EG; Hetherington K; Ziegler DS; Marshall GM; Kirk J; Marron JM; Denburg AE; Barlow-Stewart K; Warby M; Tucker KM; Lee BM; O’Brien TA; Wakefield CE; O'Brien T, 2022, 'What’s in a Name? Parents’ and Healthcare Professionals’ Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes', Journal of Personalized Medicine, 12, pp. 1327,

Journal articles | 2022

Kong BY; Carter C; Nowak AK; Hovey E; Lwin Z; Haghighi N; Gan HK; Sim HW; Ziegler DS; Barton K; Parkinson J; Leonard R; Khasraw M; Foote M, 2022, 'Barriers and potential solutions to international collaboration in neuro-oncology clinical trials: Challenges from the Australian perspective', Asia-Pacific Journal of Clinical Oncology, 18, pp. 259 - 266,

Journal articles | 2022

Lamoureux A-A; Fisher M; Lemelle L; Pfaff E; Kramm C; De Wilde B; Kazanowska B; Hutter C; Pfister SM; Sturm D; Jones D; Orbach D; Pierron G; Raskin S; Drilon A; Diamond E; Harada G; Zapotocky M; Ellezam B; Weil AG; Venne D; Barritault M; Leblond P; Coltin H; Hammad R; Tabori U; Hawkins C; Hansford JR; Meyran D; Erker C; McFadden K; Sato M; Gottardo NG; Dholaria H; Nørøxe DS; Goto H; Ziegler DS; Lin FY; Parsons DW; Lindsay H; Wong T-T; Liu Y-L; Wu K-S; Franson AF; Hwang E; Aguilar-Bonilla A; Cheng S; Cacciotti C; Massimino M; Schiavello E; Wood P; Hoffman LM; Cappellano A; Lassaletta A; Van Damme A; Llort A; Gerber NU; Ceruso MS; Bendel AE; Skrypek M; Hamideh D; Mushtaq N; Walter A; Jabado N; Alsahlawi A; Farmer J-P; Abadi CC; Mueller S; Mazewski C; Aguilera D; Robison N; O’Halloran K; Abbou S; Berlanga P; Geoerger B; Øra I; Moertel CL; Razis ED; Vernadou A; Doz F; Laetsch TW; Perreault S, 2022, 'HGG-11. Clinical characteristics and clinical evolution of a large cohort of pediatric patients with primary central nervous system (CNS) tumors and tropomyosin receptor kinase (TRK) fusion.', Neuro-Oncology, 24, pp. i61 - i62,

Journal articles | 2022

Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM; Trahair T, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. emmm202114608,

Journal articles | 2022

Lazow MA; Fuller C; Dewire M; Lane A; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Fonseca A; Garcia Lombardi M; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann C; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer R; Samson Y; Sandler ES; Sevlever G; Tinkle CL; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2022, 'Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry', Neuro-Oncology, 24, pp. 821 - 833,

Journal articles | 2022

Lazow MA; Nievelstein MT; Lane A; Bandopadhayhay P; DeWire-Schottmiller M; Fouladi M; Glod JW; Greiner RJ; Hoffman LM; Hummel TR; Kilburn L; Leary S; Minturn JE; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach JL, 2022, 'Volumetric endpoints in diffuse intrinsic pontine glioma: p correlations in the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 1598 - 1608,

Journal articles | 2022

Lehmann R; Rayner BS; Ziegler DS, 2022, 'Resistance mechanisms in BRAF^V600E paediatric high-grade glioma and current therapeutic approaches', Frontiers in Oncology, 12,

Journal articles | 2022

Pommert L; Schafer ES; Malvar J; Gossai N; Florendo E; Pulakanti K; Heimbruch K; Stelloh C; Chi YY; Sposto R; Rao S; Huynh VT; Brown P; Chang BH; Colace SI; Hermiston ML; Heym K; Hutchinson RJ; Kaplan JA; Mody R; O'Brien TA; Place AE; Shaw PH; Ziegler DS; Wayne A; Bhojwani D; Burke MJ, 2022, 'Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium', American Journal of Hematology, 97, pp. 613 - 622,

Journal articles | 2022

Tsai JW; Cejas P; Wang DK; Patel S; Wu DW; Arounleut P; Wei X; Zhou N; Syamala S; Dubois FPB; Crane A; Pelton K; Vogelzang J; Sousa C; Baguette A; Chen X; Condurat AL; Dixon-Clarke SE; Zhou KN; Lu SD; Gonzalez EM; Chacon MS; Digiacomo JJ; Kumbhani R; Novikov D; Hunter J; Tsoli M; Ziegler DS; Dirksen U; Jager N; Balasubramanian GP; Kramm CM; Nathrath M; Bielack S; Baker SJ; Zhang J; McFarland JM; Getz G; Aguet F; Jabado N; Witt O; Pfister SM; Ligon KL; Hovestadt V; Kleinman CL; Long H; Jones DTW; Bandopadhayay P; Phoenix TN, 2022, 'FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits', Cancer Research, 82, pp. 2980 - 3001,

Journal articles | 2022

Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752,

Journal articles | 2022

Whitlock JA; Malvar J; Dalla-Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown PA; Gardner RA; Gaynon PS; Hutchinson R; Huynh VT; Jeha S; Marcus L; Messinger Y; Schultz KR; Cassar J; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2022, 'Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR)', Pediatric Blood and Cancer, 69,

Journal articles | 2022

van Tilburg C; Jones DT; Schmidt R; Avula S; van Meeteren AS; Sehested A; Opocher E; Driever PH; Witt R; Ziegler D; Blackman S; Zhao X; Tsao L-P; Cox M; Hargrave D; Witt O, 2022, 'CTNI-30. LOGGIC/FIREFLY-2: A PHASE 3, RANDOMIZED TRIAL OF TOVORAFENIB VS. CHEMOTHERAPY IN PEDIATRIC PATIENTS WITH NEWLY DIAGNOSED LOW-GRADE GLIOMA HARBORING AN ACTIVATING RAF ALTERATION', Neuro-Oncology, 24, pp. vii77 - vii78,

Journal articles | 2021

Burke MJ; Ziegler DS; Bautista F; Attarbaschi A; Gore L; Locatelli F; O'Brien MM; Pauly M; Obreja M; Morris CL; Baruchel A, 2021, 'Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)', Blood, 138, pp. 1235 - 1235,

Journal articles | 2021

Chung J; Maruvka YE; Sudhaman S; Kelly J; Haradhvala NJ; Bianchi V; Edwards M; Forster VJ; Nunes NM; Galati MA; Komosa M; Deshmukh S; Cabric V; Davidson S; Zatzman M; Light N; Hayes R; Brunga L; Anderson ND; Ho B; Hodel KP; Siddaway R; Morrissy AS; Bowers DC; Larouche V; Bronsema A; Osborn M; Cole KA; Opocher E; Mason G; Thomas GA; George B; Ziegler DS; Lindhorst S; Vanan M; Yalon-Oren M; Reddy AT; Massimino M; Tomboc P; Van Damme A; Lossos A; Durno C; Aronson M; Morgenstern DA; Bouffet E; Huang A; Taylor MD; Villani A; Malkin D; Hawkins CE; Pursell ZF; Shlien A; Kunkel TA; Getz G; Tabori U, 2021, 'DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells', Cancer Discovery, 11, pp. 1176 - 1191,

Journal articles | 2021

Doz F; van Tilburg CM; Geoerger B; Nysom K; Øra I; Boni V; Chisholm J; Chung HC; DuBois SG; Melcón SG; Gerber NU; Goto H; Grilley-Olsen JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Capra M; Schulte JH; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2021, 'CTNI-58. EFFICACY AND SAFETY OF LAROTRECTINIB IN ADULT AND PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 23, pp. vi73 - vi74,

Journal articles | 2021

Durno C; Ercan AB; Bianchi V; Edwards M; Aronson M; Galati M; Atenafu EG; Abebe-Campino G; Al-Battashi A; Alharbi M; Azad VF; Baris HN; Basel D; Bedgood R; Bendel A; Ben-Shachar S; Blumenthal DT; Blundell M; Bornhorst M; Bronsema A; Cairney E; Rhode S; Caspi S; Chamdin A; Chiaravalli S; Constantini S; Crooks B; Das A; Dvir R; Farah R; Foulkes WD; Frenkel Z; Gallinger B; Gardner S; Gass D; Ghalibafian M; Gilpin C; Goldberg Y; Goudie C; Hamid SA; Hampel H; Hansford JR; Harlos C; Hijiya N; Hsu S; Kamihara J; Kebudi R; Knipstein J; Koschmann C; Kratz C; Larouche V; Lassaletta A; Lindhorst S; Ling SC; Link MP; De Mola RL; Luiten R; Lurye M; Maciaszek JL; MagimairajanIssai V; Maher OM; Massimino M; McGee RB; Mushtaq N; Mason G; Newmark M; Nicholas G; Nichols KE; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Roy S; Sabel M; Samuel D; Scheers I; Schneider KW; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Thomas G; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Zelcer S; Ziegler DS, 2021, 'Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance', Journal of Clinical Oncology, 39, pp. 2779 - 2790,

Journal articles | 2021

Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Joshi S; Rouaen JRC; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Tolhurst O; Kankean A; Hayden E; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov AV; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG', Cell Reports, 35, pp. 108994,

Journal articles | 2021

Fischer M; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin MS; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Geoerger B; Schulte JH, 2021, 'Ceritinib in paediatric patients with anaplastic lymphoma kinase-positive malignancies: an open-label, multicentre, phase 1, dose-escalation and dose-expansion study', The Lancet Oncology, 22, pp. 1764 - 1776,

Journal articles | 2021

Gamble LD; Purgato S; Henderson MJ; Di Giacomo S; Russell AJ; Pigini P; Murray J; Valli E; Milazzo G; Giorgi FM; Cowley M; Ashton LJ; Bhalshankar J; Schleiermacher G; Rihani A; Van Maerken T; Vandesompele J; Speleman F; Versteeg R; Koster J; Eggert A; Noguera R; Stallings RL; Tonini GP; Fong K; Vaksman Z; Diskin SJ; Maris JM; London WB; Marshall GM; Ziegler DS; Hogarty MD; Perini G; Norris MD; Haber M, 2021, 'A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma', Cancers, 13, pp. 1807,

Journal articles | 2021

Goudie C; Witkowski L; Cullinan N; Reichman L; Schiller I; Tachdjian M; Armstrong L; Blood KA; Brossard J; Brunga L; Cacciotti C; Caswell K; Cellot S; Clark ME; Clinton C; Coltin H; Felton K; Fernandez CV; Fleming AJ; Fuentes-Bolanos N; Gibson P; Grant R; Hammad R; Harrison LW; Irwin MS; Johnston DL; Kane S; Lafay-Cousin L; Lara-Corrales I; Larouche V; Mathews N; Meyn MS; Michaeli O; Perrier R; Pike M; Punnett A; Ramaswamy V; Say J; Somers G; Tabori U; Thibodeau ML; Toupin AK; Tucker KM; Van Engelen K; Vairy S; Waespe N; Warby M; Wasserman JD; Whitlock JA; Sinnett D; Jabado N; Nathan PC; Shlien A; Kamihara J; Deyell RJ; Ziegler DS; Nichols KE; Dendukuri N; Malkin D; Villani A; Foulkes WD, 2021, 'Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes', JAMA Oncology, 7, pp. 1806 - 1814,

Journal articles | 2021

Haeusler GM; De Abreu Lourenco R; Clark H; Thursky KA; Slavin MA; Babl FE; Mechinaud F; Alvaro F; Clark J; Padhye B; Phillips M; Super L; Tapp H; Walwyn T; Ziegler D; Phillips R; Worth LJ, 2021, 'Diagnostic Yield of Initial and Consecutive Blood Cultures in Children with Cancer and Febrile Neutropenia', Journal of the Pediatric Infectious Diseases Society, 10, pp. 125 - 130,

Journal articles | 2021

Hau P; Frappaz D; Hovey E; McCabe MG; Pajtler KW; Wiestler B; Seidel C; Combs SE; Dirven L; Klein M; Anazodo A; Hattingen E; Hofer S; Pfister SM; Zimmer C; Kortmann RD; Sunyach MP; Tanguy R; Effeney R; von Deimling A; Sahm F; Rutkowski S; Berghoff AS; Franceschi E; Pineda E; Beier D; Peeters E; Gorlia T; Vanlancker M; Bromberg JEC; Gautier J; Ziegler DS; Preusser M; Wick W; Weller M, 2021, 'Development of randomized trials in adults with medulloblastoma—the example of eortc 1634-btg/noa-23', Cancers, 13,

Journal articles | 2021

Hayden E; Holliday H; Lehmann R; Khan A; Tsoli M; Rayner BS; Ziegler DS, 2021, 'Therapeutic targets in diffuse midline gliomas—an emerging landscape', Cancers, 13,

Journal articles | 2021

Himes RW; Chiou EH; Queliza K; Shouval DS; Somech R; Agarwal S; Jajoo K; Ziegler DS; Kratz CP; Huang J; Lucas TL; Myers KC; Nelson AS; DiNardo CD; Alter BP; Giri N; Khincha PP; McReynolds LJ; Dufour C; Pierri F; Goldman FD; Sherif Y; Savage SA; Miloh T; Bertuch AA, 2021, 'Gastrointestinal Hemorrhage: A Manifestation of the Telomere Biology Disorders', Journal of Pediatrics, 230, pp. 55 - 61.e4,

Journal articles | 2021

Janjua TI; Rewatkar P; Ahmed-Cox A; Saeed I; Mansfeld FM; Kulshreshtha R; Kumeria T; Ziegler DS; Kavallaris M; Mazzieri R; Popat A, 2021, 'Frontiers in the treatment of glioblastoma: Past, present and emerging', Advanced Drug Delivery Reviews, 171, pp. 108 - 138,

Journal articles | 2021

Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, 12, pp. 971,

Journal articles | 2021

Khan S; Solano-Paez P; Suwal T; Lu M; Al-Karmi S; Ho B; Mumal I; Shago M; Hoffman LM; Dodgshun A; Nobusawa S; Tabori U; Bartels U; Ziegler DS; Hansford JR; Ramaswamy V; Hawkins C; Dufour C; André N; Bouffet E; Huang A; Gonzalez CV A; Stephens D; Leary S; Marrano P; Fonseca A; Thacker N; Li BK; Lindsay HB; Lassaletta A; Bendel AE; Moertel C; Morales La Madrid A; Santa-Maria V; Lavarino C; Rivas E; Perreault S; Ellezam B; Weil AG; Jabado N; Oviedo A; Yalon-Oren M; Amariglio L; Toledano H; Dvir R; Loukides J; Van Meter TE; Nakamura H; Wong TT; Wu KS; Cheng CJ; Ra YS; La Spina M; Massimi L; Buccoliero AM; Reddy A; Li R; Gillespie GY; Adamek D; Fangusaro J; Scharnhorst D; Torkildson J; Johnston D; Michaud J; LafayCousin L; Chan J; Van Landeghem F; Wilson B; Camelo-Piragua S; Kabbara N; Boutarbouch M; Hanson D; Jacobsen C; Wright K; Vibhakar R; Levy JM; Wang Y; Catchpoole D; Gerber N; Grotzer MA; Shen V; Plant A; Dunham C; Joao Gil da Costa M; Ramanujachar R; Raabe E; Rubens J; Phillips J; Gupta N; Demir HA; Dahl C; Jorgensen M; Hwang EI; Packer RJ; Smith A; Tan E; Low S; Lu JQ; Ng HK; Kresak JL, 2021, 'Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study', The Lancet Child and Adolescent Health, 5, pp. 800 - 813,

Journal articles | 2021

Kilburn LB; Jabado N; Franson A; Chi SN; Fisher MJ; Hargrave DR; Hansford JR; Ziegler DS; Landi D; Kang HJ; Gerber NU; Yalon-Oren M; Cornelio I; Blackman SC; Cox MC; Witt O; Prados M; Mueller S, 2021, 'FIREFLY-1: A phase 2 study of the pan-RAF inhibitor DAY101 in pediatric patients with low-grade glioma.', Journal of Clinical Oncology, 39, pp. TPS10056 - TPS10056,

Journal articles | 2021

Lazow M; Nievelstein M; Lane A; Bandopadhayay P; DeWire-Schottmiller M; Fouladi M; Glod J; Greiner R; Hoffman L; Hummel T; Kilburn L; Leary S; Minturn J; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach J, 2021, 'NIMG-11. VOLUMETRIC ENDPOINTS IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): COMPARISON TO CROSS-SECTIONAL MEASURES AND CORRELATION WITH OUTCOMES', Neuro-Oncology, 23, pp. vi129 - vi130,

Journal articles | 2021

Manoharan N; Ajuyah P; Senapati A; Wong M; Mullins A; Rodriguez M; Doyle H; McCowage G; Lau LMS; Ekert PG; Ziegler DS, 2021, 'Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis', Acta Neuropathologica Communications, 9,

Journal articles | 2021

Meyran D; Terry RL; Zhu JJ; Haber M; Ziegler DS; Ekert PG; Trapani JA; Darcy PK; Neeson PJ, 2021, 'Early-phenotype CAR-T cells for the treatment of pediatric cancers', Annals of Oncology, 32, pp. 1366 - 1380,

Journal articles | 2021

Michniewicz F; Saletta F; Rouaen JRC; Hewavisenti RV; Mercatelli D; Cirillo G; Giorgi FM; Trahair T; Ziegler D; Vittorio O, 2021, 'Copper: An Intracellular Achilles’ Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics', ChemMedChem, 16, pp. 2315 - 2329,

Journal articles | 2021

Morgenstern DA; Mascarenhas L; Campbell M; Ziegler DS; Nysom K; Casanova M; Pappo AS; Albert CM; Xia M; Barker SS; Wright J; Laetsch TW, 2021, 'Oral selpercatinib in pediatric patients (pts) with advanced RET-altered solid or primary CNS tumors: Preliminary results from the phase 1/2 LIBRETTO-121 trial.', Journal of Clinical Oncology, 39, pp. 10009 - 10009,

Journal articles | 2021

Nagabushan S; Lau LMS; Barahona P; Wong M; Sherstyuk A; Marshall GM; Tyrrell V; Wegner EA; Ekert PG; Cowley MJ; Mayoh C; Trahair TN; Crowe P; Anazodo A; Ziegler DS, 2021, 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', npj Precision Oncology, 5,

Journal articles | 2021

Perreault S; Doz F; Geoerger B; Nysom K; Øra I; Boni V; Chisholm J; DuBois SG; Gerber NU; Goto H; Grilley-Olson JE; Hansford JR; Kang HJ; Capra M; Schulte JH; Stefanowicz J; Tahara M; Ziegler DS; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; van Tilburg CM, 2021, 'RARE-07. EFFICACY AND SAFETY OF LAROTRECTINIB IN PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 23, pp. i42 - i42,

Journal articles | 2021

Robertson EG; Wakefield CE; Tsoli M; Kellie SJ; Alvaro F; Gifford AJ; Weber MA; Rodriguez M; Kirby M; Ziegler DS, 2021, 'Parents' experiences of postmortem tumor donation for high-grade gliomas: Benefits and suggested improvements', Neuro-Oncology Advances, 3, pp. vdab087,

Journal articles | 2021

Ryan AL; Burns C; Gupta AK; Samarasekera R; Ziegler DS; Kirby ML; Alvaro F; Downie P; Laughton SJ; Cross S; Hassall T; McCowage GB; Hansford JR; Kotecha RS; Gottardo NG, 2021, 'Malignant Melanoma in Children and Adolescents Treated in Pediatric Oncology Centers: An Australian and New Zealand Children’s Oncology Group (ANZCHOG) Study', Frontiers in Oncology, 11,

Journal articles | 2021

Terry RL; Meyran D; Fleuren EDG; Mayoh C; Zhu J; Omer N; Ziegler DS; Haber M; Darcy PK; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Chimeric antigen receptor t cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma', Cancers, 13, pp. 4704,

Journal articles | 2021

Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, 13, pp. 1 - 20,

Journal articles | 2021

Xiao L; Somers K; Murray J; Pandher R; Karsa M; Ronca E; Bongers A; Terry R; Ehteda A; Gamble LD; Issaeva N; Leonova KI; O’Connor A; Mayoh C; Venkat P; Quek H; Brand J; Kusuma FK; Pettitt JA; Mosmann E; Kearns A; Eden G; Alfred S; Allan S; Zhai L; Kamili A; Gifford AJ; Carter DR; Henderson MJ; Fletcher JI; Marshall G; Johnstone RW; Cesare AJ; Ziegler DS; Gudkov AV; Gurova KV; Norris MD; Haber M, 2021, 'Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma', Clinical Cancer Research, 27, pp. 4338 - 4352,

Journal articles | 2021

Xie J; Kumar A; Dolman MEM; Mayoh C; Khuong-Quang DA; Cadiz R; Wong-Erasmus M; Mould EVA; Grebert-Wade D; Barahona P; Kamili A; Tsoli M; Failes TW; Chow SO; Bhatia K; Marshall GM; Ziegler DS; Haber M; Lock RB; Tyrrell V; Lau L; Athanasatos P; Gifford AJ; Arndt G, 2021, 'The important role of routine cytopathology in pediatric precision oncology', Cancer Cytopathology, 129, pp. 805 - 818,

Journal articles | 2021

Ziegler DS; Huynh V; Burke MJ; Gore L; Locatelli F; O'Brien MM; Kim C; Obreja M; Morris CL; Baruchel A, 2021, 'Phase 2 Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)', Blood, 138, pp. 4403 - 4403,

Journal articles | 2020

Burke MJ; Kostadinov R; Sposto R; Gore L; Kelley SM; Rabik C; Trepel JB; Lee MJ; Yuno A; Lee S; Bhojwani D; Jeha S; Chang BH; Sulis ML; Hermiston ML; Gaynon P; Huynh V; Verma A; Gardner R; Heym KM; Dennis RM; Ziegler DS; Laetsch TW; Oesterheld JE; Dubois SG; Pollard JA; Glade-Bender J; Cooper TM; Kaplan JA; Farooqi MS; Yoo B; Guest E; Wayne AS; Brown PA, 2020, 'Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study', Clinical Cancer Research, 26, pp. 2297 - 2307,

Journal articles | 2020

Chen CCL; Deshmukh S; Jessa S; Hadjadj D; Lisi V; Andrade AF; Faury D; Jawhar W; Dali R; Suzuki H; Pathania M; A D; Dubois F; Woodward E; Hébert S; Coutelier M; Karamchandani J; Albrecht S; Brandner S; De Jay N; Gayden T; Bajic A; Harutyunyan AS; Marchione DM; Mikael LG; Juretic N; Zeinieh M; Russo C; Maestro N; Bassenden AV; Hauser P; Virga J; Bognar L; Klekner A; Zapotocky M; Vicha A; Krskova L; Vanova K; Zamecnik J; Sumerauer D; Ekert PG; Ziegler DS; Ellezam B; Filbin MG; Blanchette M; Hansford JR; Khuong-Quang DA; Berghuis AM; Weil AG; Garcia BA; Garzia L; Mack SC; Beroukhim R; Ligon KL; Taylor MD; Bandopadhayay P; Kramm C; Pfister SM; Korshunov A; Sturm D; Jones DTW; Salomoni P; Kleinman CL; Jabado N, 2020, 'Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis', Cell, 183, pp. 1617 - 1633.e22,

Journal articles | 2020

Clarke M; Mackay A; Ismer B; Pickles JC; Tatevossian RG; Newman S; Bale TA; Stoler I; Izquierdo E; Temelso S; Carvalho DM; Molinari V; Burford A; Howell L; Virasami A; Fairchild AR; Avery A; Chalker J; Kristiansen M; Haupfear K; Dalton JD; Orisme W; Wen J; Hubank M; Kurian KM; Rowe C; Maybury M; Crosier S; Knipstein J; Schüller U; Kordes U; Kram DE; Snuderl M; Bridges L; Martin AJ; Doey LJ; Al-Sarraj S; Chandler C; Zebian B; Cairns C; Natrajan R; Boult JKR; Robinson SP; Sill M; Dunkel IJ; Gilheeney SW; Rosenblum MK; Hughes D; Proszek PZ; Macdonald TJ; Preusser M; Haberler C; Slavc I; Packer R; Ng HK; Caspi S; Popović M; Kotnik BF; Wood MD; Baird L; Davare MA; Solomon DA; Olsen TK; Brandal P; Farrell M; Cryan JB; Capra M; Karremann M; Schittenhelm J; Schuhmann MU; Ebinger M; Dinjens WNM; Kerl K; Hettmer S; Pietsch T; Andreiuolo F; Driever PH; Korshunov A; Hiddingh L; Worst BC; Sturm D; Zuckermann M; Witt O; Bloom T; Mitchell C; Miele E; Colafati GS; Diomedi-Camassei F; Bailey S; Moore AS; Hassall TEG; Lowis SP; Tsoli M; Cowley MJ; Ziegler DS; Karajannis MA; Aquilina K; Hargrave DR; Carceller F; Marshall LV, 2020, 'Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes', Cancer Discovery, 10, pp. 942 - 963,

Journal articles | 2020

Dodgshun AJ; Fukuoka K; Edwards M; Bianchi VJ; Das A; Sexton-Oates A; Larouche V; Vanan MI; Lindhorst S; Yalon M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Ashraf S; Farah R; Van Damme A; Opocher E; Hamid SA; Ziegler DS; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas GA; Lossos A; Sullivan M; Hansford JR; Mackay A; Jones C; Jones DTW; Ramaswamy V; Hawkins C; Bouffet E; Tabori U, 2020, 'Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns', Acta Neuropathologica, 140, pp. 765 - 776,

Journal articles | 2020

Gedye C; Sachchithananthan M; Leonard R; Jeffree RL; Buckland ME; Ziegler DS; Graeber MB; Day BW; McDonald KL; Lasocki A; Back M; Besser M; Boyd A; Byrne J; Cher L; Cook R; Day J; Davidson A; Devereux L; Dexter M; Donnelly R; Drummond K; Eckstein L; Gan H; Garrick T; Gottardo N; Harper C; Johns T; Khasraw M; Kichenadasse G; Eng-Siew K; Lipworth W; Ludlow L; Moore A; Munoz L; Nahar N; Olson S; Ormsby R; Parkinson J; Partanen A; Raymond E; Reddel R; Robbins P; Rosenthal M; Saunus J; Shivalingam B; Simes J; Stringer B; Thorne H; Vajdic C; Varikatt W; Walker D; Wheeler H; White D; Yip S; Nowak AK, 2020, 'Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking', Neuro-Oncology Practice, 7, pp. 31 - 37,

Journal articles | 2020

Goldsmith KC; Verschuur A; Morgenstern DA; van Eijkelenburg N; Federico SM; Fraser C; Forlenza CJ; Ziegler DS; Gerber NU; Khaw SL; Cooper TM; Flotho C; Prine BA; Salem AH; Unnebrink K; Tong B; Palenski TL; Place AE, 2020, 'The first report of pediatric patients with solid tumors treated with venetoclax.', Journal of Clinical Oncology, 38, pp. 10524 - 10524,

Journal articles | 2020

Goto H; Geoerger B; DuBois SG; Grilley-Olson JE; van Tilburg CM; Schulte J; Kang HJ; Tahara M; Boni V; Perreault S; Capra M; Reeves JA; Brega N; Childs BH; Laetsch TW; Ziegler DS; Doz F, 2020, 'EPCT-08. ACTIVITY OF LAROTRECTINIB IN PEDIATRIC TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 22, pp. iii305 - iii305,

Journal articles | 2020

Hanson D; Andre N; Chi S; Filbin M; Fisher M; Hoffman L; Khatib Z; Kool M; Narendran A; Pizer B; Slavc I; Vogel T; Ziegler D; Kieran M, 2020, 'ETMR-08. INTERNATIONAL CONSENSUS PROTOCOL FOR EMBRYONAL TUMOR WITH MULTILAYER ROSETTES', Neuro-Oncology, 22, pp. iii324 - iii324,

Journal articles | 2020

Hanson D; Hoffman LM; Nagabushan S; Goumnerova LC; Rathmann A; Vogel T; Ziegler DS; Chi S, 2020, 'A modified IRS-III chemotherapy regimen leads to prolonged survival in children with embryonal tumor with multilayer rosettes', Neuro-Oncology Advances, 2,

Journal articles | 2020

Khuong-Quang DA; Brown LM; Wong M; Mayoh C; Sexton-Oates A; Kumar A; Pinese M; Nagabushan S; Lau L; Ludlow LE; Gifford AJ; Rodriguez M; Desai J; Fox SB; Haber M; Ziegler DS; Hansford JR; Marshall GM; Cowley MJ; Ekert PG; Wong-Erasmus M, 2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, 6, pp. mcs.a005710,

Journal articles | 2020

Lazow MA; Fuller C; Lane A; DeWire-Schottmiller MD; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Lombardi MG; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann CJ; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer RJ; Samson Y; Sandler ES; Sevlever G; Tinkle C; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2020, 'DIPG-46. NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW', Neuro-Oncology, 22, pp. iii295 - iii296,

Journal articles | 2020

Leach JL; Roebker J; Schafer A; Baugh J; Chaney B; Fuller C; Fouladi M; Lane A; Doughman R; Drissi R; DeWire-Schottmiller M; Ziegler DS; Minturn JE; Hansford JR; Wang SS; Monje-Deisseroth M; Fisher PG; Gottardo NG; Dholaria H; Packer R; Warren K; Leary SES; Goldman S; Bartels U; Hawkins C; Jones BV, 2020, 'MR imaging features of diffuse intrinsic pontine glioma and relationship to overall survival: Report from the International DIPG Registry', Neuro-Oncology, 22, pp. 1647 - 1657,

Journal articles | 2020

Li BK; Vasiljevic A; Dufour C; Yao F; Ho BLB; Lu M; Hwang EI; Gururangan S; Hansford JR; Fouladi M; Nobusawa S; Laquerriere A; Delisle MB; Fangusaro J; Forest F; Toledano H; Solano-Paez P; Leary S; Birks D; Hoffman LM; Szathmari A; Faure-Conter C; Fan X; Catchpoole D; Zhou L; Schultz KAP; Ichimura K; Gauchotte G; Jabado N; Jones C; Loussouarn D; Mokhtari K; Rousseau A; Ziegler DS; Tanaka S; Pomeroy SL; Gajjar A; Ramaswamy V; Hawkins C; Grundy RG; Hill DA; Bouffet E; Huang A; Jouvet A, 2020, 'Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study', Acta Neuropathologica, 139, pp. 223 - 241,

Journal articles | 2020

McGill BC; Wakefield CE; Hetherington K; Munro LJ; Warby M; Lau L; Tyrrell V; Ziegler DS; O’brien TA; Marshall GM; Malkin D; Hansford JR; Tucker KM; Vetsch J; O'Brien T, 2020, '“Balancing Expectations with Actual Realities”: Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 10, pp. 9,

Journal articles | 2020

Michniewicz F; Saletta F; Rouen J; Ziegler D; Vittorio O, 2020, 'DIPG-83. USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', Neuro-Oncology, 22, pp. iii303 - iii303,

Journal articles | 2020

Perreault S; Doz F; Drilon A; Geoerger B; Boni V; Chisholm J; Dubois SG; Grilley-Olson JE; Hong DS; Italiano A; Kang H; Nysom K; Øra I; Owens C; Schulte JH; Tahara M; Ziegler D; Ellezam B; Reeves JA; Fellous M; De La Cuesta E; Laetsch TW; van Tilburg CM, 2020, 'CTNI-67. EFFICACY AND SAFETY OF LAROTRECTINIB IN PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS: AN EXPANDED DATASET', Neuro-Oncology, 22, pp. ii58 - ii58,

Journal articles | 2020

Schulte JH; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin M; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Fischer M; Geoerger B, 2020, 'Final analysis of phase I study of ceritinib in pediatric patients with malignancies harboring activated anaplastic lymphoma kinase (ALK).', Journal of Clinical Oncology, 38, pp. 10505 - 10505,

Journal articles | 2020

Shen H; Yu M; Tsoli M; Chang C; Joshi S; Liu J; Ryall S; Chornenkyy Y; Siddaway R; Hawkins C; Ziegler DS, 2020, 'Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas', Neuro-Oncology, 22, pp. 139 - 151,

Journal articles | 2020

Terry RL; Meyran D; Ziegler DS; Haber M; Ekert PG; Trapani JA; Neeson PJ, 2020, 'Immune profiling of pediatric solid tumors', Journal of Clinical Investigation, 130, pp. 3391 - 3402,

Journal articles | 2020

Vetsch J; Hetherington K; Wakefield C; Ziegler D, 2020, 'Families’ experiences of a precision medicine trial for childhood cancer', Oncology Central

Journal articles | 2020

Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ; O'Brien T; Wong-Erasmus M, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, 26, pp. 1742 - 1753,

Journal articles | 2020

Wood P; Desai J; Waldeck K; Cain J; Gottardo N; Strong R; Kinross K; Carr M; Jones J; Wong L; Ziegler D; Hansford J; Michael M; Ashley D, 2020, 'ATRT-08. A PHASE II STUDY OF CONTINUOUS LOW DOSE PANOBINOSTAT IN PAEDIATRIC PATIENTS WITH MALIGNANT RHABDOID TUMORS/ATYPICAL TERATOID RHABDOID TUMORS', Neuro-Oncology, 22, pp. iii277 - iii277,

Journal articles | 2019

Burke MJ; Ziegler DS; Bautista Sirvent FJ; Attarbaschi A; Gore L; Locatelli F; O'Brien MM; Pauly M; Obreja M; Morris CL; Baruchel A, 2019, 'Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)', Blood, 134, pp. 3873 - 3873,

Journal articles | 2019

Doz F; Geoerger B; DuBois SG; Grilley-Olson JE; van Tilburg CM; Italiano A; Lissat A; Jin Kang H; Tahara M; Boni V; Perreault S; Capra M; Nanda S; Brega N; Holynskyj A; Ziegler DS; Hong DS; Hyman DM; Drilon A, 2019, 'RARE-45. ACTIVITY OF LAROTRECTINIB IN TRK FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS', Neuro-Oncology, 21, pp. vi231 - vi231,

Journal articles | 2019

Drilon AE; DuBois SG; Farago AF; Geoerger B; Grilley-Olson JE; Hong DS; Sohal D; van Tilburg CM; Ziegler DS; Ku N; Cox MC; Nanda S; Childs BH; Doz FP, 2019, 'Activity of larotrectinib in TRK fusion cancer patients with brain metastases or primary central nervous system tumors.', Journal of Clinical Oncology, 37, pp. 2006 - 2006,

Journal articles | 2019

DuBois SG; Albert CM; Mascarenhas L; Laetsch TW; van Tilburg CM; Potter SL; Turpin B; Glade Bender JL; Spunt SL; Hladun R; Casanova M; Ziegler DS; Morgenstern DA; Eary T; Ibabekci S; Qamoos H; Rothenberg SM; Cox MC; Balis FM; Pappo AS, 2019, 'A phase I study of LOXO-292, a highly selective RET inhibitor, in pediatric patients with RET-altered cancers.', Journal of Clinical Oncology, 37, pp. TPS10066 - TPS10066,

Journal articles | 2019

Franshaw L; Tsoli M; Byrne J; Mayoh C; Sivarajasingam S; Norris M; Marshall GM; Ziegler DS, 2019, 'Predictors of Success of Phase II Pediatric Oncology Clinical Trials', Oncologist, 24, pp. e765 - e774,

Journal articles | 2019

Franshaw L; Tsoli M; Lau LMS; Ziegler DS, 2019, 'Translating palbociclib to the clinic for DIPG - What is truly achievable?', EBioMedicine, 45, pp. 22,

Journal articles | 2019

Fultang L; Gamble LD; Gneo L; Berry AM; Egan SA; De Bie F; Yogev O; Eden GL; Booth S; Brownhill S; Vardon A; McConville CM; Cheng PN; Norris MD; Etchevers HC; Murray J; Ziegler DS; Chesler L; Schmidt R; Burchill SA; Haber M; De Santo C; Mussai F, 2019, 'Macrophage-derived IL1B and TNFa regulate arginine metabolism in neuroblastoma', Cancer Research, 79, pp. 611 - 624,

Journal articles | 2019

Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, 11,

Journal articles | 2019

Hanson D; Chi S; Ziegler D, 2019, 'MEDU-38. A CASE SERIES OF CHILDREN WITH EMBRYONAL TUMOR WITH MULTILAYER ROSETTES TREATED WITH A MODIFIED IRS-III CHEMOTHERAPY BACKBONE', Neuro-Oncology, 21, pp. ii111 - ii111,

Journal articles | 2019

Li B; Vasiljevic A; Dufour C; Ho B; Hwang E; Gururangan S; Hansford J; Laquerriere A; Delisle M-B; Fangusaro J; Forest F; Sumihito N; Toledano H; Birks D; Fan X; Fouladi M; Gajjar A; Gauchotte G; Hoffman L; Jones C; Loussouarn D; Mokhtari K; Pomeroy S; Rousseau A; Somers G; Taylor M; Ziegler DS; Lu M; Hawkins C; Grundy R; Jouvet A; Bouffet E; Ashley Hill D; Huang A, 2019, 'PDTM-24. PINEOBLASTOMA SEGREGATES INTO MOLECULAR SUBTYPES WITH DISTINCT CLINICOPATHOLOGIC FEATURES: REPORT FROM THE RARE BRAIN TUMOUR CONSORTIUM', Neuro-Oncology, 21, pp. vi192 - vi192,

Journal articles | 2019

Rampersaud E; Ziegler DS; Iacobucci I; Payne-Turner D; Churchman ML; Schrader KA; Joseph V; Offit K; Tucker K; Sutton R; Warby M; Chenevix-Trench G; Huntsman DG; Tsoli M; Scott Mead R; Qu C; Leventaki V; Wu G; Mullighan CG, 2019, 'Germline deletion of ETV6 in familial acute lymphoblastic leukemia', Blood Advances, 3, pp. 1039 - 1046,

Journal articles | 2019

Robertson EG; Wakefield CE; Cohn RJ; Battisti RA; Donoghoe MW; Ziegler DS; Fardell JE; Mitchell R; O'Brien TA, 2019, 'Piloting a parent and patient decision aid to support clinical trial decision making in childhood cancer', Psycho-Oncology, 28, pp. 1520 - 1529,

Journal articles | 2019

Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo N; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma', Journal of Neuro-Oncology, 141, pp. 253 - 263,

Journal articles | 2019

Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo NG; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma (Journal of Neuro-Oncology, (2019), 141, 2, (253-263), 10.1007/s11060-018-03038-2)', Journal of Neuro-Oncology, 141, pp. 265,

Journal articles | 2019

Vetsch J; Wakefield CE; Duve E; McGill BC; Warby M; Tucker KM; Malkin D; Lau L; Ziegler DS, 2019, 'Parents', health care professionals', and scientists' experiences of a precision medicine pilot trial for patients with high-risk childhood cancer: A qualitative study', JCO Precision Oncology, 3, pp. 1 - 11,

Journal articles | 2019

Vetsch J; Wakefield CE; Techakesari P; Warby M; Ziegler DS; O'Brien TA; Drinkwater C; Neeman N; Tucker K, 2019, 'Healthcare professionals’ attitudes toward cancer precision medicine: A systematic review', Seminars in Oncology, 46, pp. 291 - 303,

Journal articles | 2019

Ziegler DS; Doz F; Geoerger B; Dubois S; Grilley-Olson JE; van Tilburg C; Italiano A; Lissat A; Kang J-H; Tahara M; Boni V; Perreault S; Capra M; Nanda S; Brega N; Holynskyj A; Hong DS; Hyman D; Drilon A, 2019, 'Activity of larotrectinib in TRK fusion cancer patients with primary central nervous system tumours', Annals of Oncology, 30, pp. ix124 - ix124,

Journal articles | 2018

Allanson BM; Weber MA; Jackett LA; Chan C; Lau L; Ziegler D; Warby M; Mayoh C; Cowley MJ; Tucker KM; Long GV; Maher A; Anazodo A; Scolyer RA, 2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma.', Pathology, 50, pp. 648 - 653,

Journal articles | 2018

Allanson BM; Weber MA; Jackett LA; Chan C; Lau L; Ziegler DS; Warby M; Mayoh C; Cowley MJ; Tucker KM; Long GV; Maher A; Anazodo A; Scolyer RA, 2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma', Pathology, 50, pp. 648 - 653,

Journal articles | 2018

Bartlett A; Cochrane A; Lane A; Yanez-Escorza N; Chaney B; Doughman R; DeWire-Schottmiller M; Goldman S; Warren K; Bandopadhayay P; Foreman N; Shih C-S; Minturn J; Bartels U; Packer R; Nazarian J; Hassall T; Samson Y; Monje-Deisseroth M; Fisher P; Wagner L; Koschmann C; Ziegler D; Kieran M; Hawkins C; White P; Dexheimer P; Hendershot J; Drissi R; Fuller C; Leach J; Jones B; Fouladi M, 2018, 'DIPG-70. CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN <3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, 20, pp. i63 - i63,

Journal articles | 2018

Dixon F; Ziegler DS; Bajuk B; Wright I; Hilder L; Abdel Latif ME; Somanathan A; Oei JL, 2018, 'Treatment with nitric oxide in the neonatal intensive care unit is associated with increased risk of childhood cancer', Acta Paediatrica, International Journal of Paediatrics, 107, pp. 2092 - 2098,

Journal articles | 2018

Dodgshun A; Fukuoka K; Campbell B; Edwards M; Sexton-Oates A; Larouche V; Magimairajan V; Lindhorst S; Oren M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Shamvil A; Farah R; van Damme A; Opocher E; Hamid SA; Ziegler D; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas G; Lossos A; Saffery R; Sullivan M; Hansford JR; Jones D; Tabori U, 2018, 'HGG-20. DNA METHYLATION ANALYSIS OF HIGH-GRADE GLIOMA IN PATIENTS WITH MISMATCH REPAIR DEFICIENCIES', Neuro-Oncology, 20, pp. i92 - i93,

Journal articles | 2018

Erker C; Lane A; Chaney B; Escorza NY; Fuller C; Saab R; Kieran M; Packer R; Nazarian J; Minturn J; Dodgshun A; Parkin S; Foreman N; Broxson E; Lombardi MG; Goldman S; Sandler E; Warren K; Greiner R; Gottardo N; Dholaria H; Shih C-S; Hassall T; Hansford JR; Wang SS; Samson Y; Leary S; Ma J; Bartels U; Broniscer A; Monje M; Fisher P; Ziegler D; Wagner L; Koschmann C; Doughman R; Drissi R; Jones B; Leach J; White P; Dexheimer P; Hendershot J; Hawkins C; Bandopadhayay P; Fouladi M, 2018, 'DIPG-69. CHARACTERISTICS OF PATIENTS ≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, 20, pp. i63 - i63,

Journal articles | 2018

Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, 18, pp. 389 - 400,

Journal articles | 2018

Hoffman LM; Van Zanten SEMV; Colditz N; Baugh J; Chaney B; Hoffmann M; Lane A; Fuller C; Miles L; Hawkins C; Bartels U; Bouffet E; Goldman S; Leary S; Foreman NK; Packer R; Warren KE; Broniscer A; Kieran MW; Minturn J; Comito M; Broxson E; Shih CS; Khatua S; Chintagumpala M; Carret AS; Escorza NY; Hassall T; Ziegler DS; Gottardo N; Dholaria H; Doughman R; Benesch M; Drissi R; Nazarian J; Jabado N; Boddaert N; Varlet P; Giraud G; Castel D; Puget S; Jones C; Hulleman E; Modena P; Giagnacovo M; Antonelli M; Pietsch T; Gielen GH; Jones DTW; Sturm D; Pfister SM; Gerber NU; Grotzer MA; Pfaff E; Von Bueren AO; Hargrave D; Solanki GA; Cvrlje FJ; Kaspers GJL; Vandertop WP; Grill J; Bailey S; Biassoni V; Massimino M; Calmon R; Sanchez E; Bison B; Warmuth-Metz M; Leach J; Jones B; Van Vuurden DG; Kramm CM; Fouladi M, 2018, 'Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A collaborative report from the International and European Society for Pediatric Oncology DIPG registries', Journal of Clinical Oncology, 36, pp. 1963 - 1972,

Journal articles | 2018

Kabalan P; Gifford AJ; Ziegler DS, 2018, 'Unresectable VIP-secreting neuroblastoma: Efficacy of debulking and steroids for symptom control', Pediatric Blood and Cancer, 65,

Journal articles | 2018

Li BK; Vasiljevic A; Ho B; Jouvet A; Hwang EI; Hansford JR; Laquerriere A; Delisle M-B; Gururangan S; Fangusaro JR; Forest F; Sumihito N; Toledano H; Fouladi M; Gauchotte G; Ziegler DS; Bouffet E; Grundy RG; Dufour C; Huang AA, 2018, 'Genomic landscape of pineoblastoma.', Journal of Clinical Oncology, 36, pp. 2028 - 2028,

Journal articles | 2018

Marachelian A; Hogarty MD; Flynn A; Liu K; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer C; Norris M; Haber M; Groshen SG; Ziegler DS; Matthay KK, 2018, 'NANT 2012-01: Phase 1 study of DFMO and celecoxib with cyclophosphamide and topotecan for relapsed or refractory high-risk neuroblastoma.', JOURNAL OF CLINICAL ONCOLOGY, 36,

Journal articles | 2018

Michaiel G; Strother D; Gottardo N; Bartels U; Coltin H; Eisenstat DD; Hukin J; Johnston DL; Wilson B; Zelcer S; Hansford JR; Wells O; AbdelBaki MS; Abu-Arja MH; Cole KA; Dhall G; Fisher PG; Hoffman L; Leary SES; Pickle EEO; Smiley NP; Smith A; Vinitsky A; Vitanza NA; Wright A; Yeo KK; Chow LML; Kirby M; Valvi S; Vanan MI; Wong G; Ziegler D; Bouffet E; Lafay-Cousin L, 2018, 'GERM-23. INTRACRANIAL GROWING TERATOMA SYNDROME (IGTS): AN INTERNATIONAL RETROSPECTIVE STUDY', Neuro-Oncology, 20, pp. i88 - i88,

Journal articles | 2018

Robertson EG; Wakefield CE; Cohn RJ; O'Brien T; Ziegler DS; Fardell JE, 2018, 'The development of delta: Using agile to develop a decision aid for pediatric oncology clinical trial enrollment', JMIR Research Protocols, 7, pp. e119,

Journal articles | 2018

Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023,

Journal articles | 2018

Sun W; Malvar J; Sposto R; Verma A; Wilkes JJ; Dennis R; Heym K; Laetsch TW; Widener M; Rheingold SR; Oesterheld J; Hijiya N; Sulis ML; Huynh V; Place AE; Bittencourt H; Hutchinson R; Messinger Y; Chang B; Matloub Y; Ziegler DS; Gardner R; Cooper T; Ceppi F; Hermiston M; Dalla-Pozza L; Schultz KR; Gaynon P; Wayne AS; Whitlock JA, 2018, 'Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study', Leukemia, 32, pp. 2316 - 2325,

Journal articles | 2018

Tsoli M; Liu J; Franshaw L; Shen H; Cheng C; Jung MS; Joshi S; Ehteda A; Khan A; Montero-Carcabosso A; Dilda PJ; Hogg P; Ziegler DS, 2018, 'Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma', Oncotarget, 9, pp. 7541 - 7556,

Journal articles | 2018

Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS; Arndt G, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, 19, pp. 1078 - 1087,

Journal articles | 2018

Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall GM; Trahair T; Sivarajasingam S; Ziegler DS, 2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, 40, pp. 541 - 547,

Journal articles | 2018

Ziegler DS; Wong M; Mayoh C; Kumar A; Tsoli M; Mould E; Tyrrell V; Khuong-Quang DA; Pinese M; Gayevskiy V; Cohn RJ; Lau LMS; Reynolds M; Cox MC; Gifford A; Rodriguez M; Cowley MJ; Ekert PG; Marshall GM; Haber M; Wong-Erasmus M, 2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, 119, pp. 693 - 696,

Journal articles | 2017

Baugh J; Bartels U; Leach J; Jones B; Chaney B; Warren KE; Kirkendall J; Doughman R; Hawkins C; Miles L; Fuller C; Hassall T; Bouffet E; Lane A; Hargrave D; Grill J; Hoffman LM; Jones C; Towbin A; Savage SA; Monje M; Li XN; Ziegler DS; Veldhuijzen van Zanten S; Kramm CM; van Vuurden DG; Fouladi M, 2017, 'The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease', Journal of Neuro-Oncology, 132, pp. 323 - 331,

Journal articles | 2017

Bhojwani D; Burke MJ; Horton T; Ziegler DS; Sulis ML; Schultz KR; Wayne A; Izraeli S; Chang BH, 2017, 'Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group', Pediatric Hematology and Oncology, 34, pp. 355 - 364,

Journal articles | 2017

Campbell BB; Angelini P; Fabrizio D; Elvin J; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole K; Opocher E; Thomas G; Sabel M; George B; Ziegler D; Lapierre N; Mason G; Magimajrajan V; Shlien A; Tabori U, 2017, 'IMMU-13. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A��DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. iv30 - iv30,

Journal articles | 2017

Campbell BB; Angelini P; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole KA; Opocher E; Sabel M; George B; Ziegler D; Laperriere N; Meyn S; Malkin D; Shlien A; Tabori U, 2017, 'PDTM-21. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A��DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. vi194 - vi194,

Journal articles | 2017

Campbell BB; Light N; Fabrizio D; Zatzman M; Fuligni F; de Borja R; Davidson S; Edwards M; Elvin JA; Hodel KP; Zahurancik WJ; Suo Z; Lipman T; Wimmer K; Kratz CP; Bowers DC; Laetsch TW; Dunn GP; Johanns TM; Grimmer MR; Smirnov IV; Larouche V; Samuel D; Bronsema A; Osborn M; Stearns D; Raman P; Cole KA; Storm PB; Yalon M; Opocher E; Mason G; Thomas GA; Sabel M; George B; Ziegler DS; Lindhorst S; Issai VM; Constantini S; Toledano H; Elhasid R; Farah R; Dvir R; Dirks P; Huang A; Galati MA; Chung J; Ramaswamy V; Irwin MS; Aronson M; Durno C; Taylor MD; Rechavi G; Maris JM; Bouffet E; Hawkins C; Costello JF; Meyn MS; Pursell ZF; Malkin D; Tabori U; Shlien A, 2017, 'Comprehensive Analysis of Hypermutation in Human Cancer', Cell, 171, pp. 1042 - 1056.e10,

Journal articles | 2017

Durno CA; Aronson M; Edwards M; Ling S; Larouche V; Bronsema A; Osborn M; Stearns D; Cole K; Oren M; Opocher E; Mason GE; Thomas G; Sabel M; George B; Ziegler D; Lindhorst S; Magimairajan V; Laperriere N; Samuel D; Bouffet E; Tabori U, 2017, 'Immune Check Point Inhibitor Treatment for Young Patients with Hypermutant Cancers', Gastroenterology, 152, pp. S141 - S141,

Journal articles | 2017

Hennika T; Hu G; Olaciregui NG; Barton KL; Ehteda A; Chitranjan A; Chang C; Gifford AJ; Tsoli M; Ziegler DS; Carcaboso AM; Becher OJ, 2017, 'Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models', PLoS ONE, 12, pp. e0169485,

Journal articles | 2017

Lapin DH; Tsoli M; Ziegler DS, 2017, 'Genomic insights into diffuse intrinsic pontine glioma', Frontiers in Oncology, 7, pp. 57,

Journal articles | 2017

Sadras T; Heatley SL; Kok CH; McClure BJ; Yeung D; Hughes TP; Sutton R; Ziegler DS; White DL, 2017, 'A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH', Cancer Genetics, 216-217, pp. 86 - 90,

Journal articles | 2017

Valvi S; Ziegler DS, 2017, 'Ganglioglioma arising from desmoplastic medulloblastoma: A case report and review of literature', Pediatrics, 139,

Journal articles | 2016

Barbaro PM; Ziegler DS; Reddel RR, 2016, 'The wide-ranging clinical implications of the short telomere syndromes', Internal Medicine Journal, 46, pp. 393 - 403,

Journal articles | 2016

Davis T; Doyle H; Tobias V; Ellison DW; Ziegler DS, 2016, 'Case report of spontaneous resolution of a congenital glioblastoma', Pediatrics, 137,

Journal articles | 2016

Evageliou NF; Haber M; Vu A; Laetsch TW; Murray J; Gamble LD; Cheng NC; Liu K; Reese M; Corrigan KA; Ziegler DS; Webber H; Hayes CS; Pawel B; Marshall GM; Zhao H; Gilmour SK; Norris MD; Hogarty MD, 2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, 22, pp. 4391 - 4404,

Journal articles | 2016

Franshaw L; Sivarajasingam S; Byrne J; Dalla-Pozza L; Marshall G; Norris M; Ziegler DS, 2016, 'Predictors of success of phase 2 paediatric oncology clinical trials', European Journal of Cancer, 69, pp. S63 - S64,

Journal articles | 2016

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232,

Journal articles | 2015

Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7, pp. 312ra176,

Journal articles | 2015

Ziegler DS, 2015, 'Never say never', Journal of Clinical Oncology, 33, pp. 518 - 520,

Journal articles | 2014

Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, 50, pp. 135,

Journal articles | 2014

Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, 1, pp. 59 - 77,

Journal articles | 2014

Vedi A; ziegler D, 2014, 'Antibody therapy for pediatric leukemia', Frontiers in Oncology, 4, pp. 1 - 10,

Journal articles | 2014

Whitlock J; dalla Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown P; Gardner RA; Gaynon PS; Hutchinson RJ; Marcus LJ; Messinger YH; Schultz KR; Vandergiessen J; Eckroth E; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2014, 'Nelarabine in Combination with Etoposide and Cyclophosphamide Is Active in First Relapse of Childhood T-Acute Lymphocytic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LL)', Blood, 124, pp. 795 - 795,

Journal articles | 2014

Williams P; Wegner E; Ziegler DS, 2014, 'Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome', Pediatrics, 134,

Journal articles | 2013

Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, 60, pp. 1520 - 1527,

Journal articles | 2013

Shah S; Schrader KA; Vijai J; Miething C; Hayes J; Klein RJ; Gao X; Kitzing T; Lowe SW; Offit K; Littman J; Offit L; Rau-Murthy R; Fleischut MH; Corines M; Manschreck C; Waanders E; Wei L; Ma J; Chen S-C; Song G; Cheng J; Raimondi SC; Roberts KG; Downing JR; Mullighan CG; Kuiper RP; Simons A; Timms AE; Wechsler J; Horwitz MS; Yang J; Zhang J; Wu G; Rusch M; Nagahawatte P; Meyers P; Bhojwani D; Sandlund JT; Jhanwar S; Murali R; Maslak P; Fleisher M; Murty VV; Schiffman JD; Onel K; Plon SE; Wheeler DA; Ritter D; Ziegler DS; Sutton R; Tucker K; Chenevix-Trench G; Li J; Huntsman DG; Hansford S; Senz J; Walsh T; Lee M; King M-C; Hahn CN; Scott HS; Lo SM; Levine RL; Viale A; Socci ND; Nathanson KL; Daly M; Lipkin SM; Altshuler D, 2013, 'A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia', Nature Genetics, 45, pp. 1226 - 1231,

Journal articles | 2012

Argent E; Emder PJ; Monagle P; Mowat DR; Petterson T; Russell SJ; Sachdev RR; Stone C; Ziegler DS, 2012, 'Australian paediatric surveillance unit study of haemoglobinopathies in australian children', Journal of Paediatrics and Child Health, 48, pp. 356 - 360,

Journal articles | 2012

Bock V; Ziegler DS; Wargon O; Gray PEA, 2012, 'Neonatal Sweet Syndrome: A potential marker of serious systemic illness', Pediatrics, 129, pp. e1353 - e1359,

Journal articles | 2012

Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M; Gamble L, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, 2, pp. 1 - 10,

Journal articles | 2012

Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, 11, pp. 2654 - 2663,

Journal articles | 2012

Ziegler D, 2012, 'Erratum: Treatment of diabetic neuropathy and neuropathic pain: How far have we come? (Diabetes Care (2008) 31 Suppl. 2, (S255-S261) DOI: 10.2337/dc08-s263)', Diabetes Care, 35, pp. 456,

Journal articles | 2011

Barbaro PM; Johnston K; Dalla-Pozza L; Cohn RJ; Wang YA; Marshall GM; Ziegler DS, 2011, 'Reduced incidence of second solid tumors in survivors of childhood Hodgkin's lymphoma treated without radiation therapy', Annals of Oncology, 22, pp. 2569 - 2574,

Journal articles | 2011

Kamath V; Sugo E; Ziegler DS; Kwok B; Lukeis R, 2011, 'Atypical teratoid/rhaboid tumour arising in association with a pleomorphic xanthoastrocytoma: a case report', Pathology, 43, pp. S76 - S76,

Journal articles | 2011

McCowage G; Mrongovius R; Alvaro F; Cohn RJ; Ziegler DS; Oswald CM; White L, 2011, 'Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: An Australian and New Zealand children's hematology and oncology group study', Pediatric Blood and Cancer, 57, pp. 958 - 964,

Journal articles | 2011

Ziegler D; Rosentock J; Portenoy R, 2011, 'Effective management of diabetic neuropathy - Pregabalin relieves the neuropathic pain', Diabetes Aktuell, 9, pp. 237,

Journal articles | 2011

Ziegler DS; Keating J; Kesari S; Fast EM; Zawel L; Ramakrishnan N; Barnes J; Kieran MW; Van zanten SEMV; Kung AL, 2011, 'A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo', Neuro - Oncology, 13, pp. 820 - 829,

Journal articles | 2010

Ueberberg S; Ziegler D; Schechinger W; Dietrich JW; Akinturk S; Klein HH; Schneider S, 2010, 'In vitro phage display in a rat beta cell line: A simple approach for the generation of a single-chain antibody targeting a novel beta cell-specific epitope', Diabetologia, 53, pp. 1384 - 1394,

Journal articles | 2009

Satharasinghe K; Trahair TN; Barbaric D; O'Brien TA; Russell SJ; Cohn RJ; Marshall GM; Ziegler DS, 2009, 'False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma', Journal of Clinical Oncology, 27,

Journal articles | 2008

Ziegler DS; Klung A, 2008, 'Therapeutic targeting of apoptosis pathways in cancer', Current Opinion Oncology, 20, pp. 97 - 103

Journal articles | 2008

Ziegler DS; Kung A; Kieran M, 2008, 'Anti-apoptosis mechanisms in malignant gliomas', Journal of Clinical Oncology, 26, pp. 493 - 500,

Journal articles | 2008

Ziegler DS; Wright R; Kesari S; Lemieux M; Tran M; Jain M; Zawei L; Kung A, 2008, 'Resistance of human glioblastoma multiformed cells to growth factor inhibitor of apoptosis proteins', The Journal of Clinical Investigation, 2118, pp. 3109 - 3122

Journal articles | 2008

Ziegler DS; Wright RD; Kesari S; Lemieux ME; Tran MA; Jain M; Zawel L; Kung AL, 2008, 'Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins', Journal of Clinical Investigation, 118, pp. 3109 - 3122,

Journal articles | 2006

Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald CM; Mrongovius R; White L, 2006, 'Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors', Neuro - Oncology, 8, pp. 53 - 59

Journal articles | 2006

Ziegler DS; McCowage G; Cohn RJ; White L, 2006, 'Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood', Journal of Pediatric Hematology and Oncology, 28, pp. 40 - 42

Journal articles | 2005

Haysom L; Ziegler DS; Cohn RJ; Rosenberg A; Carroll SL; Kainer G, 2005, 'Retinoic acid may increase the risk of bone marrow transplant nephrology', Pediatric Nephrology, 20, pp. 534 - 538

Journal articles | 2005

Hocking B; Ziegler DS; Dalla Pozza L; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia (multiple letters) [2]', Medical Journal of Australia, 182, pp. 364 - 365,

Journal articles | 2005

Ziegler DS; Cohn RJ; Duffy B; Sutton R; Norris MD, 2005, 'PCR for monoclonal gene rearrangements can differentiate infantile acute lymphoblastic leukemia from cytomegalovirus infection', Leukemia Research, 29, pp. 111 - 112

Journal articles | 2005

Ziegler DS; Dalla Pozza L; Waters K; Marshall GM, 2005, 'Advances in childhood leukaemia: successful clinical-trials research leads to individualised therapy', Medical Journal of Australia, 182, pp. 78 - 81

Journal articles | 2005

Ziegler DS; Piper AC; Sammut J, 2005, 'Physical injury in young children: The differential diagnosis must include child abuse (vol 41, pg 251, 2005)', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 41, pp. 474 - 474,

Journal articles | 2005

Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia - Reply', MEDICAL JOURNAL OF AUSTRALIA, 182, pp. 365 - 365,

Journal articles | 2005

Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia', Medical Journal of Australia, 182, pp. 364 - 365,

Journal articles | 2005

Ziegler DS; Russell SJ; Rozenberg G; James CA; Trahair TN; O'Brien TA, 2005, 'Goats' milk quackery', Journal of Paediatrics and Child Health, 41, pp. 569 - 571

Journal articles | 2005

Ziegler DS; Sammut JF; Piper AC, 2005, 'Assessment and follow up of suspected child abuse in preschool children with fractures seen in a general hospital emergency department.', Journal of Paediatrics and Child Health (Vol. 48, Suppl. 2, 2012, 1–13), 41, pp. 251 - 255,

Journal articles | 2003

Scanlon DM; Ziegler DS; Mantzouranis EC; Boicos SA; Bagourakis GS, 2003, 'Throat clearing in asthma [5] (multiple letters)', New England Journal of Medicine, 349, pp. 194 - 195,

Journal articles | 2001

Ziegler D; Bent G, 2001, 'Caustic-induced upper airway obstruction responsive to nebulized adrenaline [5]', Pediatrics, 107, pp. 807 - 808,

Journal articles | 2001

Ziegler DS; Bent GP, 2001, 'Upper airway obstruction induced by a caustic substance found responsive to nebulised adrenaline [3]', Journal of Paediatrics and Child Health, 37, pp. 524 - 525,
Preprints | 2024

Fuentes-Bolanos N; Courtney E; Mayoh C; Warby M; Lau L; Wong-Erasmus M; Khuong-Quang D-A; Barahona P; Padhye B; El-Kamand S; Nunag S; Ajuyah P; Sherstyuk A; Altekoester A-K; Sullivan A; Poplawski N; Kiraly-Borri C; O’Sullivan S; Marfan H; Alli R; Curnow L; Bhatia K; Anazodo A; Trahair T; Mateos M; Hansford J; Dholaria H; Josephi-Taylor S; Moore A; Nicholls W; Gottardo N; Downie P; Khaw S-L; Tapp H; McCowage G; Dalla-Pozza L; Alvaro F; Wood P; Tyrrell V; Haber M; Cowley M; Ekert P; Marshall G; Kirk J; Tucker K; Pinese M; Ziegler D, 2024, Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer,

Preprints | 2024

Holliday H; Khan A; Ehteda A; Ross S; Jayatilleke N; Gopalakrishnan A; Guo X; Liu J; Nguyen H; Lee A; Sanguino YC; Dinger M; Mayoh C; Rayner B; Tsoli M; Ziegler D, 2024, Chromatin remodeling with combined FACT and BET inhibition disrupts oncogenic transcription in Diffuse Midline Glioma,

Conference Abstracts | 2024

Tax G; Mao J; Cadiz R; Barhen T; Xie J; Harris J; Bae M; Brown LM; Pazaky K; Gifford AJ; Mayoh C; Mateos MK; Peterziel H; Oehme I; Ziegler DS; Tsoli M; Rayner B; Ekert PG; Dolman MEM, 2024, 'Abstract B003: Expanding therapeutic horizons: Unleashing the untapped potential of MEK inhibitor treatment in pediatric cancers', in Cancer Research, American Association for Cancer Research (AACR), Vol. 84, pp. B003 - B003,

Preprints | 2023

Duchatel RJ; Jackson ER; Parackal SG; Sun C; Daniel P; Mannan A; Findlay IJ; Staudt D; Germon ZP; Laternser S; Kiltschewskij D; Kearney PS; Fairuz M; Jamaluddin B; Douglas AM; Beitaki T; Persson M; Manning EE; Murray HC; Verrills NM; Skerrett-Byrne DA; Nixon B; Hua S; Fatima V-M; Tsoli M; Ziegler DS; Cairns MJ; Raabe E; Vitanza NA; Koschmann C; Alvaro F; Dayas CV; Tinkle CL; Eisenstat DD; Firestein R; Mueller S; Nazarian J; Cain JE; Dun MD, 2023, PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma,

Preprints | 2023

Fordham A; Brown L; Mayoh C; Salib A; Barger Z; Wong M; Sian TCCLK; Xie J; Gunther K; Trebilcock P; Terry R; Barahona P; Ajuyah P; Sherstyuk A; Avila A; Cadiz R; Perkins C; Gifford A; Mao J; Zhao A; O’Regan L; Gorgels D; Lau LMS; Ziegler D; Haber M; Tyrrell V; Lock R; Cowley M; Nicholls W; Daly R; Ekert P; Fleuren EDG, 2023, Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas,

Preprints | 2023

Kelada L; Robertson E; McKay S; McGill B; Daly R; Mazariego C; Taylor N; Tyedmers E; Evans HE; Wakefield C; Ziegler D, 2023, Communicating with families of young people with hard-to-treat cancers: Healthcare professionals’ perspectives on challenges, skills, and training,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures and Figure Legends from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures and Figure Legends from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Materials and Methods from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Materials and Methods from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Tables S1-S7 from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Other | 2023

Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Tables S1-S7 from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer,

Conference Abstracts | 2023

Nagabushan S; Hamayun M; Fardell JE; Donoghoe M; Bland E; Bye A; Jacobson E; Manoharan N; Ziegler DS; McLoone JK; Johnson AM; Cohn RJ, 2023, 'LGG-11. COGNITIVE, ACADEMIC, AND QUALITY OF LIFE OUTCOMES IN SURVIVORS OF PEDIATRIC LOW-GRADE GLIOMA: CHALLENGING THE ‘BENIGN TUMOR’ PERCEPTION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 25, pp. i57 - i58,

Preprints | 2023

Ziegler D; Lau L; Khuong-Quang D-A; Mayoh C; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester A-K; Fuentes-Bolanos N; Yeung V; Sullivan A; Diamond Y; Omer N; Jessop S; Battaglia L; Zhukova N; Cui L; Lin A; Gifford A; Fleuren E; Dalla-Pozza L; Moore A; Khaw S; Eisenstat D; Gottardo N; Wood P; Tapp H; Alvaro F; McCowage G; Nicholls W; Hansford J; Manoharan N; Kotecha R; Mateos M; Lock R; Tyrrell V; Haber M; Trahair T; Cowley M; Ekert P; Marshall G, 2023, Precision-guided treatment improves outcomes for children with high-risk cancers,

Conference Abstracts | 2022

Brown MP; Gargett T; Ebert LM; Truong N; Sedivakova K; Kollis PM; Yu W; Yeo E; Vittorio O; Ziegler DS, 2022, 'Immunotherapy: IN VITRO STUDIES IN SUPPORT OF GD2-SPECIFIC CAR-T CELL THERAPY FOR AGGRESSIVE ADULT AND PEDIATRIC BRAIN TUMORS', in Cytotherapy, Elsevier BV, Vol. 24, pp. S125 - S125,

Conference Abstracts | 2022

Cooney T; DeWire-Schottmiller M; Lane A; Saab R; Bandopadhayay P; Dorris K; Packer R; Kilburn L; Minturn J; Dodgshun A; Parkin S; Goldman S; Sandler E; Greiner R; Gottardo N; Dholaria H; Coven S; Hassall T; Hansford J; Samson Y; Leary S; Bartels U; Fonseca A; Bouffet E; Tinkle C; Monje M; Fisher P; Ziegler D; Chintagumpala M; Wagner L; Koschmann C; Leach J; Jones B; Benito EC; Bond H; Chaney B; Black K; Asher A; Fouladi M; Hoffman L; Warren K, 2022, 'PATTERNS OF CEREBROSPINAL FLUID DIVERSION AND SURVIVAL IN CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 24, pp. 23 - 24,

Conference Abstracts | 2022

Daniel P; Sun C; Koptyra M; Drinkwater C; Chew N; Bradshaw G; Loi M; Shi C; Tourchi M; Parackal S; Chong WC; Fernando D; Adjumain S; Hoang N; Habarakada D; Sooraj D; Crombie D; Zhukova N; Jones C; Rubens J; Raabe E; Vinci M; Dun M; Ludlow L; Nazarian J; Fletcher J; Ekert P; Ziegler D; Loh AHP; Low SYY; Monje M; Neeman N; Williams B; Resnick A; Gough D; Cain J; Firestein R, 2022, 'THE CHILDHOOD BRAIN CANCER CELL LINE ATLAS: A RESOURCE FOR BIOMARKER IDENTIFICATION AND THERAPEUTIC DEVELOPMENT', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 172 - 172, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022,

Conference Abstracts | 2022

Das A; Morgenstern D; Bianchi V; Sudhaman S; Edwards M; Stengs L; Larouche V; Samuel D; Van Damme A; Gass D; Ziegler D; Bielack S; Zelcer S; Yalon M; Constantini S; Sarosiek T; Libionka W; Nichols K; De Mola RL; Bielamowicz K; Sabel M; Frojd C; Wood MD; Sous Migueis JC; Abongwa C; Yen LY; Stearns D; Opocher E; Bhatia K; Sen S; Quiroga Cantero E; Solano Paez P; Crooks B; Magimairajan V; Reddy A; Adamski J; Mason G; Lindhorst S; Aronson M; Ertl-Wagner B; Hawkins C; Bouffet E; Tabori U, 2022, 'DUAL CTLA4/PD-1 BLOCKADE IMPROVES SURVIVAL FOR REPLICATION-REPAIR DEFICIENT HIGH-GRADE GLIOMAS FAILING SINGLE AGENT PD-1 INHIBITION: AN IRRDC STUDY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 84 - 84, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022,

Preprints | 2022

Gargett T; Ebert L; Truong NTH; Kollis P; Sedivakova K; Yu W; Yeo ECF; Wittwer N; Gliddon B; Tea M; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler D; Pitson S; Brown M, 2022, GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma,

Conference Abstracts | 2022

Gereis J; Hetherington K; Robertson E; Ziegler D; Wakefield C, 2022, 'PARENTS' AND PATIENTS' UNDERSTANDING OF A PRECISION MEDICINE TRIAL FOR HIGH-RISK CHILDHOOD CANCER', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 69, pp. S399 - S399,

Conference Abstracts | 2022

Holliday H; Ehteda A; Khan A; Krug B; Rouaen JRC; Jayatilleke N; Mayoh C; Vittorio O; Jabado N; Tsoli M; Ziegler DS, 2022, 'DIPG-06. Uncovering the FACTs in Diffuse Midline Glioma (DMG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i18 - i18,

Conference Abstracts | 2022

Holliday H; Ehteda A; Khan A; Krug B; Rouaen JRC; Jayatilleke N; Mayoh C; Vittorio O; Jabado N; Tsoli M; Ziegler DS, 2022, 'UNCOVERING THE FACTS IN DIFFUSE MIDLINE GLIOMA (DMG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 24, pp. 18 - 18,

Conference Abstracts | 2022

Landi DB; Ziegler DS; Franson AF; Baxter PA; Leary S; Larouche V; Waanders AJ; Van der Lugt J; McCowage GB; Doz F; Jabado N; Schiavello E; Zapotocky M; Cornelio I; Blackman SC; Da Costa D; Cox MC; Witt O; Kilburn LB; Hansford JR, 2022, 'FIREFLY-1 (PNOC 026): A phase 2 study to evaluate the safety and efficacy of tovorafenib (DAY101) in pediatric patients with RAF-altered recurrent or progressive low-grade glioma or advanced solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. TPS10062 - TPS10062,

Preprints | 2022

Lilly JV; Rokita JL; Mason JL; Patton T; Stefankiewiz S; Higgins D; Trooskin G; Larouci CA; Arya K; Appert E; Heath AP; Zhu Y; Brown MA; Zhang B; Farrow BK; Robins S; Morgan AM; Nguyen TQ; Frenkel E; Lehmann K; Drake E; Sullivan C; Plisiewicz A; Coleman N; Patterson L; Koptyra M; Helili Z; Van Kuren N; Young N; Kim MC; Friedman C; Lubneuski A; Blackden C; Williams M; Baubet V; Tauhid L; Galanaugh J; Boucher K; Ijaz H; Cole KA; Choudhari N; Santi M; Moulder RW; Waller J; Rife W; Diskin SJ; Mateos M; Parsons DW; Pollack IF; Goldman S; Leary S; Caporalini C; Buccoliero AM; Scagnet M; Haussler D; Hanson D; Firestein R; Cain J; Phillips JJ; Gupta N; Mueller S; Grant G; Monje-Deisseroth M; Partap S; Greenfield JP; Hashizume R; Smith A; Zhu S; Johnston JM; Fangusaro JR; Miller M; Wood MD; Gardner S; Carter CL; Prolo LM; Pisapia J; Pehlivan K; Franson A; Niazi T; Rubin J; Abdelbaki M; Ziegler DS; Lindsay HB; Stucklin AG; Gerber N; Vaske OM; Quinsey C; Rood BR; Nazarian J; Raabe E; Jackson EM; Stapleton S; Lober RM; Kram DE; Koschmann C; Storm PB; Lulla RR; Prados M; Resnick AC; Waanders AJ, 2022, The Children’s Brain Tumor Network (CBTN) - Accelerating Research in Pediatric Central Nervous System Tumors through Collaboration and Open Science,

Preprints | 2022

Mayoh C; Gifford A; Terry R; Lau LMS; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang D-A; Qin V; Mateos M; Meyran D; Miller K; Yuksel A; Mould EVA; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore A; Nicholls W; Gottardo N; McCowage G; Hansford J; Khaw S-L; Wood P; Catchpoole D; Cottrell C; Mardis E; Marshall G; Tyrrell V; Haber M; Ziegler D; Vittorio O; Trapani J; Cowley M; Neeson P; Ekert P, 2022, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer,

Conference Abstracts | 2022

Mayoh C; Meyran D; Nguyen T; Darcy C; Ziegler D; Haber M; Trapani J; Ekert P; Neeson P, 2022, 'PRECISION MEDICINE REVEALS A HETEROGENOUS TUMOUR IMMUNE MICROENVIRONMENT IN PAEDIATRIC GLIOMAS', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 69, pp. S327 - S328,

Conference Abstracts | 2022

Mazariego CG; Dobson M; McKay S; McGill B; Daly R; Wakefield C; Ziegler D; Taylor N, 2022, 'Designing for implementation: co-design of a paediatric oncology medicines database (ProCure) to support complex care provision for children with a hard-to-treat cancer', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 18, pp. 229 - 229,

Conference Abstracts | 2022

Michniewicz F; Bell J; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Barlow CK; Faridi P; Tsoli M; Ziegler D; Vittorio O, 2022, 'COPPER CHELATION THERAPY TARGETS S-ADENOSYLMETHIONINE (SAM) METABOLISM AND EPIGENETIC REGULATORS IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 22 - 22, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022,

Conference Abstracts | 2022

Michniewicz F; Bell J; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Barlow CK; Faridi P; Tsoli M; Ziegler D; Vittorio O, 2022, 'DIPG-20. Copper chelation therapy targets S-adenosylmethionine (SAM) metabolism and epigenetic regulators in diffuse intrinsic pontine glioma (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i22 - i22,

Conference Posters | 2022

Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Abstract 5716: Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG)', Vol. 82, pp. 5716 - 5716,

Conference Papers | 2022

Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG)', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022,

Conference Papers | 2022

Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG).', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022,

Preprints | 2022

Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Zheng Y; Rouaen J; Jue TR; Michniewicz FT; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Valli E; Brettle M; Whan R; Vahadat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, 2022, Copper chelation inhibits TGF-βpathways and suppresses epithelial-mesenchymal transition in cancer,

Conference Abstracts | 2022

Sanguino YC; de la Fuente LR; Kisswani D; Kearney P; Jackson E; Duchatel R; Holliday H; Jabado N; Tsoli M; Ziegler D; Dun M; Mora FV, 2022, 'DIPG-37. Exploring the role of the epigenetic factor H2A.Z acetylation in DIPG', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i26 - i27,

Conference Abstracts | 2022

Sanguino YC; de la Fuente LR; Kisswani D; Kearney P; Jackson E; Duchatel R; Holliday H; Jabado N; Tsoli M; Ziegler D; Dun M; Mora FV, 2022, 'EXPLORING THE ROLE OF THE EPIGENETIC FACTOR H2A.Z ACETYLATION IN DIPG', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 26 - 27, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022,

Conference Abstracts | 2022

Ung C; Upton DH; Venkat P; Pandher R; Curnis F; Corti A; Nicolazzo J; Mayoh C; Tsoli M; Ziegler DS, 2022, 'DIPG CELLS ALTER THE PERMEABILITY OF THE BLOOD-BRAIN BARRIER IN THE BRAINSTEM LEADING TO TREATMENT FAILURE', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 22 - 22, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022,

Conference Abstracts | 2022

Upton D; George S; Liu J; Cai DD; Su SY-C; Rayner B; Tsoli M; Ziegler D, 2022, 'DIPG-08. The development of ACT001 as a novel therapeutic for diffuse intrinsic pontine gliomas', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i19 - i19,

Conference Abstracts | 2022

Upton D; George S; Liu J; Cai DD; Su SY-C; Rayner B; Tsoli M; Ziegler D, 2022, 'THE DEVELOPMENT OF ACT001 AS A NOVEL THERAPEUTIC FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 24, pp. 19 - 19,

Conference Abstracts | 2022

Wood P; Desai J; Waldeck K; Cain J; Gottardo N; Strong R; Kinross K; Carr M; Jones J; Wong L; Ziegler D; Hansford J; Michael M; Ashley D, 2022, 'ATRT-17. A phase II study of continuous low dose panobinostat in paediatric patients with malignant rhabdoid tumours and atypical teratoid rhabdoid tumours.', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i6 - i7,

Conference Papers | 2021

Das A; Morgenstern D; Sudhaman S; Coblentz A; Chung J; Stone S; Alsafwani N; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira L; Constantini S; Dvir R; Yalon-Oren M; Campino G; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; Mola R; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler D; George B; Damme A; Hijiya N; Gass D; Mcgee R; Mordechai O; Bowers D; Laetsch T; Lossos A; Blumenthal D; Sarosiek T; Yen L; Knipstein J; Bendel A; Hoffmann L; Luna-Fineman S; Zimmermann S; Scheers I; Nichols K; Zapotocky M; Hansford J; Maris J; Dirks P; Taylor M; Kulkarni A; Shroff M; Tsang D; Villani A; Aronson M; Durno C; Shlein A; Malkin D; Getz G; Maruvka Y; Ohashi P; Hawkins C; Pugh T; Bouffet E; Tabori U, 2021, 'Mutation and Microsatellite Burden Predict Response to PD-1 Inhibition in Children With Germline DNA Replication Repair Deficiency', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S95 - S96,

Conference Abstracts | 2021

Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Hayden E; Rouaen J; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Kankean A; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov A; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION IN DIPG', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 18 - 19,

Conference Abstracts | 2021

Khan A; Gamble L; Upton D; Yu D; Pandher R; Mayoh C; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 40 - 41,

Conference Presentations | 2021

Lau L; Khuong-Quang D-A; Nagabushan S; Senapati A; Barahona P; Ajuyah P; Altekoester A-K; Wong M; Mayoh C; Mould E; Fuentes-Bolanos N; Zhukova N; Cowley M; Ekert P; Tyrrell V; Trahair T; Haber M; Marshall G; Ziegler D, 2021, 'Precision Medicine for High-Risk Paediatric Cancers - Molecular Tumour Board Recommendations and Treatment Responses (Zero Childhood Cancer Program)',

Conference Abstracts | 2021

Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers', in Cancer Research, American Association for Cancer Research (AACR), Vol. 81, pp. 3044 - 3044,

Conference Abstracts | 2021

Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'The unexplored immune landscape of high-risk pediatric cancers.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 81,

Preprints | 2021

Tabori U; Morgenstern D; Sudhaman S; Das A; Coblentz A; Chung J; Stone S; Alsafwani N; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira L; Constantini S; Dvir R; Yalon M; Campino G; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; De Mola R; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler D; George B; Damme AV; Hijaya N; Gass D; McGee R; Mordechai O; Bowers D; Laetsch T; Lossos A; Blumenthal D; Sarosiek T; Yen L; Knipstein J; Bendel A; Hoffman L; Luna-Fineman S; Zimmermann S; Scheers I; Nichols K; Zapotocky M; Hansford J; Maris J; Dirks P; Taylor M; Kulkarni A; Shroff M; Tsang D; Malkin D; Villani A; Aronson M; Durno C; Shlien A; Getz G; Maruvka Y; Ohashi P; Hawkins C; Pugh T; Bouffet E, 2021, Mutation and Microsatellite Burden Predict Response to PD-1 Inhibition in Children with Germline DNA Replication Repair Deficiency,

Conference Abstracts | 2021

Ung C; Upton D; Tsoli M; Ziegler D, 2021, 'HGG-10. THE BLOOD-BRAIN BARRIER IN DIPG: INVESTIGATING REGION-SPECIFIC DIFFERENCES IN PERMEABILITY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 23, pp. i19 - i19,

Conference Abstracts | 2021

Upton D; George S; Liu J; Cai D; Su SY-C; Manoharan N; Foresto S; Hassall T; Tsoli M; Ziegler D, 2021, 'ACT001-A PROMISING THERAPEUTIC FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 20 - 20,

Conference Abstracts | 2021

Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Reynolds P; Tsoli M; Ziegler D, 2021, 'POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 42 - 42,

Conference Abstracts | 2020

Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. A52 - A52,

Conference Abstracts | 2020

Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang D-A; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O’Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2020, 'Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. A03 - A03,

Conference Papers | 2020

Chung J; Maruvka Y; Sudhaman S; Kelly J; Haradhvala N; Bianchi VJ; Edwards M; Forster V; Nunes N; Galati M; Komosa M; Deshmukh S; Cabric V; Davidson S; Zatzman M; Light N; Hayes R; Brunga L; Anderson N; Ho B; Hodel K; Siddaway R; Morrissy AS; Bowers D; Larouche V; Bronsema A; Osborn M; Cole K; Opocher E; Mason G; Thomas G; George B; Ziegler D; Lindhorst S; Issai VM; Oren M; Reddy A; Massimino M; Tomboc P; Van Damme A; Lossos A; Durno C; Aronson M; Morgenstern D; Bouffet E; Huang A; Taylor M; Vilani A; Malkin D; Hawkins C; Pursell Z; Shlien A; Kunkel T; Getz G; Tabori U, 2020, 'DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Nomral and Malignant Human Cells', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S4 - S5,

Conference Papers | 2020

Das A; Bianchi V; Edwards M; Varghese N; Sudhaman S; Farah R; Dvir R; Reddy A; Raskin S; Hansford J; Hamid SA; Hsu S; Yen LY; Abu Quider A; Ghalibafian M; Koustenis E; Al-Battashi A; Mason G; Lee J; Bell D; Stearns D; Ziegler D; Zapotocky M; Lasaletta A; Kulkarni A; Tsang DS; Laperriere N; Hawkins C; Bouffet E; Ramaswamy V; Tabori U, 2020, 'POOR SURVIVAL IN REPLICATION REPAIR DEFICIENT HYPERMUTANT MEDULLOBLASTOMA AND CNS EMBRYONAL TUMORS: A REPORT FROM THE INTERNATIONAL RRD CONSORTIUM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 407 - 407,

Conference Papers | 2020

Das A; Bianchi VJ; Edwards M; Sudhaman S; Varghese N; Farah R; Dvir R; Reddy A; Raskin S; Hansford J; Hamid SA; Saunders H; Yen LY; Abu Quider A; Ghalibafian M; Koustenis E; Al-Battashi A; Stearns D; Ziegler D; Zapotocky M; Lassaletta A; Mason G; Lee J; Kulkarni A; Tsang D; Laperriere N; Hawkins C; Bouffet E; Ramaswamy V; Tabori U, 2020, 'Poor Survival in DNA-Replication Repair Deficient (RRD) Medulloblastoma and CNS-Embryonal Tumors is Related to High-Risk Genomic Features: A Report From the International RRD Consortium', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S54 - S55,

Conference Papers | 2020

Dodgshun A; Fukuoka K; Edwards M; Bianchi V; Sexton-Oates A; Larouche V; Magimairajan V; Lindhorst S; Yalon M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Shamvil A; Farah R; Van Damme A; Opocher E; Hamid SA; Ziegler D; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas G; Lossos A; Sullivan M; Hansford JR; Jones D; Mackay A; Jones C; Ramaswamy V; Hawkins C; Bouffet E; Tabori U, 2020, 'DIAGNOSTIC AND BIOLOGICAL ROLE OF METHYLATION PATTERNS IN REPLICATION REPAIR DEFICIENT HIGH GRADE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 347 - 348,

Conference Abstracts | 2020

Dong-Anh K-Q; Nagabushan S; Manoharan N; Arndt G; Barahona P; Cowley MJ; Ekert PG; Failes T; Bolanos NF; Gauthier M; Gifford AJ; Haber M; Kumar A; Lock RB; Marshall GM; Mayoh C; Mould E; Norris MD; Gopalakrishnan A; Omer N; Trebilcock P; Trahair TN; Tsoli M; Tucker K; Wong M; Tyrrell V; Lau L; Ziegler DS, 2020, 'PRECISION MEDICINE FOR PAEDIATRIC HIGH-GRADE DIFFUSE MIDLINE GLIOMAS - RESULTS FROM THE ZERO CHILDHOOD CANCER COMPREHENSIVE PRECISION MEDICINE PROGRAM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 22, pp. 302 - 302,

Conference Abstracts | 2020

Duchatel RJ; Mannan A; Jackson ER; Staudt D; Skerrett-Byrne DA; Jamaluddin MFB; Woldu AS; Douglas A; Hulleman E; Carcaboso AM; Monje M; Alvaro F; Tsoli M; Ziegler DS; Dun MD, 2020, 'DIPG-29. PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE (PI3K) INHIBITION DRIVES PROTEIN KINASE C ACTIVATION (PKC) IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii293,

Conference Abstracts | 2020

Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii292,

Conference Papers | 2020

Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 292 - 292,

Conference Papers | 2020

Ercan A; Durno C; Bianchi V; Edwards M; Aronson M; Villani A; Bouffet E; Al-Battashi A; Alharbi M; Basel D; Bedgood R; Bendel A; Blumenthal D; Bornhorst M; Bronsema A; Cairney E; Caroll S; Chamdin A; Chiaravalli S; Constantini S; Das A; Dvir R; Farah R; Foulkes W; Frenkel Z; Gardner S; Ghalibafian M; Gilpin C; Goudie C; Hamid SA; Hampel H; Hansford J; Harlos C; Hijiya N; Saunders H; Kamihara J; Knipstein J; Koschmann C; Larouche V; Lassaletta A; Lindhorst S; Ling S; Link M; DeMola RL; Luiten R; Lurye M; Maciaszek J; Issai VM; Maher O; Massimino M; Mushtaq N; Newmark M; Nicholas G; Nichols K; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Sabel M; Samuel D; Scheers I; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Zelcer S; Ziegler D; Zimmermann S; Azad VF; Roy S; Tabori U, 2020, 'Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Syndrome Who Undergo a Surveillance Protocol: A Report From the International Replication Repair Deficiency Consortium', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S17 - S18,

Conference Papers | 2020

Ercan AB; Durno C; Bianchi VJ; Edwards M; Aronson M; Bouffet E; Al-Battashi A; Alharbi M; Basel D; Bedgood R; Bendel A; Blumenthal DT; Bornhorst M; Bronsema A; Cairney E; Carroll S; Chamdin A; Chiaravalli S; Constantini S; Das A; Dvir R; Farah R; Foulkes W; Frenkel Z; Gardner S; Ghalibafian M; Gilpin C; Goudie C; Hamid SA; Hansford J; Harlos C; Hijiya N; Hsu S; Kamihara J; Knipstein J; Koschmann C; Larouche V; Lassaletta A; Lindhorst S; Ling S; Link M; De Mola RL; Luiten R; Lurye M; Maciaszek J; Magimairajan V; Maher O; Massimino M; Mushtaq N; Newmark M; Nicholas G; Nichols K; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Sabel M; Samuel D; Scheers I; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Azad VF; Zelcer S; Ziegler D; Zimmerman S; Tabori U, 2020, 'SURVIVAL BENEFIT FOR INDIVIDUALS WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME AND BRAIN TUMORS WHO UNDERGO SURVEILLANCE PROTOCOL. A REPORT FROM THE INTERNATIONAL REPLICATION REPAIR CONSORTIUM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 445 - 446,

Conference Abstracts | 2020

Franshaw L; Hayden E; Joshi S; Liu J; Ehteda A; Pang CNI; Tsoli M; Ziegler DS, 2020, 'DIPG-14. TARGETING POLO-LIKE KINASE 1 IN COMBINATION WITH KEY ONCOGENIC DRIVERS IN DIPG: FROM SINGLE AGENT TO COMBINATION STRATEGIES', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii289,

Conference Papers | 2020

Franshaw L; Hayden E; Joshi S; Liu J; Ehteda A; Pang CNI; Tsoli M; Ziegler DS, 2020, 'TARGETING POLO-LIKE KINASE 1 IN COMBINATION WITH KEY ONCOGENIC DRIVERS IN DIPG: FROM SINGLE AGENT TO COMBINATION STRATEGIES', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 289 - 289,

Conference Papers | 2020

Goldsmith KC; Verschuur A; Morgenstern DA; van Eijkelenburg N; Federico SM; Fraser C; Forlenza CJ; Ziegler DS; Gerber NU; Khaw SL; Cooper TM; Flotho C; Prine BA; Salem AH; Unnebrink K; Tong B; Palenski TL; Place AE, 2020, 'The first report of pediatric patients with solid tumors treated with venetoclax.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020,

Conference Abstracts | 2020

Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Dong AKQ; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020,

Conference Abstracts | 2020

Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 22, pp. 290 - 290,

Conference Abstracts | 2020

Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'DIPG-16. COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii290 - iii290,

Conference Abstracts | 2020

Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'DIPG-15. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii290,

Conference Papers | 2020

Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 289 - 290,

Conference Papers | 2020

Khan S; Solano-Paez P; Suwal T; Al-Karmi S; Lu M; Ho B; Fouladi M; Leary S; Levy JMM; Lassaletta A; Rivas E; Reddy A; Gillespie GY; Gupta N; Yalon-Oren M; Amariglio L; Nakamura H; Wu K-S; Wong T-T; Ra Y-S; La Spina M; Emanuele PV; Massimi L; Buccoliero AM; Hansford JR; Grundy RG; Adamek D; Fangusaro J; Scharnhorst D; Johnston D; Lafay-Cousin L; Camelo-Piragua S; Kabbara N; Gajjar A; Boutarbouch M; Gil da Costa MJ; Hanson D; Wood P; Al-Hussaini M; Amayiri N; Wang Y; Catchpoole D; Michaud J; Bendel AE; Ellezam B; Gerber N; Plant A; Jeffery R; Dunham C; Moertel C; Walter A; Ziegler D; Dodgshun A; Gottardo N; Demir A; Ramanujachar R; Raabe E; Mary S; Dirks P; Taylor M; Eugene H; Lindsey H; Tihan T; Mette J; Dahl C; Low S; Smith A; Hazrati L-N; Kresak J; Gino S; Tan E; Morales A; Santa-Maria V; Hawkins C; Bartels U; Stephens D; Nobusawa S; Dufour C; Bourdeaut F; Andre N; Bouffet E; Huang A, 2020, 'TITLE: DEFINING THE CLINICAL AND PROGNOSTIC LANDSCAPE OF EMBRYONAL TUMORS WITH MULTI-LAYERED ROSETTES (ETMRS), A RARE BRAIN TUMOR REGISTRY (RBTC) STUDY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 328 - 328,

Preprints | 2020

Khan S; Solano-Paez P; Suwal T; Lu M; Al-Karmi S; Ho B; AlmeidaGonzalez CV; Stephens D; Dodgshun A; Shago M; Marrano P; Fonseca A; Hoffman LM; Leary S; Lindsay HB; Lassaletta A; Bendel AE; Moertel C; Morales A; Santa-Maria V; Lavarino C; Rivas E; Perreault S; Ellezam B; Jabado N; Oviedo A; Yalon-Oren M; Amariglio L; Toledano H; Loukides J; Van Meter TE; Nakamura H; Wong T-T; Wu K-S; Cheng C-J; Ra Y-S; La Spina M; Massimi L; Buccoliero AM; Reddy A; Li R; Gillespie GY; Adamek D; Fangusaro J; Scharnhorst D; Torkildson J; Johnston D; Michaud J; Lafay-Cousin L; Chan J; Van Landeghem F; Wilson B; Camelo-Piragua S; Kabbara N; Boutarbouch M; Hanson D; Jacobsen C; Wright K; Mulcahy Levy JM; Wang Y; Catchpoole D; Gerber N; Grotzer MA; Shen V; Plant A; Dunham C; da Costa MJG; Ramanujachar R; Raabe E; Rubens J; Philips J; Gupta N; Demir A; Dahl C; Jorgensen M; Hwang EI; Smith A; Tan E; Low S; Lu J-Q; Ho-Keung NG; Kresak JL; Gururangan S; Pomeroy SL; Sirachainan N; Hongeng S; Magimairajan V; Sinha R; Mushtaq N; Antony R; Sato M; Samuel D; Zapotocky M; Afzal S; Amayiri N; Al-Hussaini M; Walter A; Tihan T; Somers GR; Gajjar A; Wood P; Gottardo N; Cain JE; Downie PA; Branson H; Laughlin S; Ertl-Wagner B; Tsang DS; Ramaswamy V; Drake J; Kulkarni AV; Ziegler DS; Nobusawa S; Tabori U; Taylor MD; Ibrahim GM; Rutka JT; Dirks PB; Hazrati L-N; Grundy RG; Fouladi M; Padovani PL; Bourdeaut F; Hansford JR; Bartels U; Dufour C; Hawkins C; Andre N; Bouffet E; Huang A, 2020, Clinical phenotypes and prognostic features of ETMRs (Embryonal Tumor with Multi-layered Rosettes) a new CNS tumor entity: A Rare Brain Tumor Registry study,

Conference Papers | 2020

Lafay-Cousin L; Lane A; Schafer A; Saab R; Cheng S; Bandopadhayay P; Zaghloul M; El-Ayadi M; Dorris K; Packer R; Kilburn L; Minturn J; Dodgshun A; Parkin S; Garcia Lombardi M; Cohen K; Gass D; Goldman S; Sandler E; Warren K; Greiner R; Gottardo N; Dholaria H; Hassall T; Coven S; Hansford J; Samson Y; Leary S; Bartels U; Bouffet E; Ma J; Tinkle C; Monje-Deisseroth M; Fisher P; Tsui K; Ziegler D; Chintagumpala M; Gururangan S; Wagner L; Koschmann C; DeWire-Schottmiller M; Leach J; Jones B; Fuller C; Drissi R; Chaney B; Black K; Fouladi M; Strother D, 2020, 'RE-IRRADIATION OF DIPG: DATA FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 301 - 302,

Conference Papers | 2020

Lazow M; Fuller C; Lane A; DeWire M; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney T; Coven S; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher P; Lombardi MG; Greiner R; Goldman S; Gottardo N; Gururangan S; Hansford J; Hassall T; Hawkins C; Kilburn L; Koschmann C; Leary S; Ma J; Minturn J; Monje M; Packer R; Samson Y; Sandler ES; Sevlever G; Tinkle C; Tsui K; Wagner L; Zaghloul M; Ziegler D; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones B; Leach J, 2020, 'NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ELECTR NETWORK, pp. 154 - 154, presented at 25th Virtual Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO), ELECTR NETWORK, 19 November 2020 - 21 November 2020,

Conference Papers | 2020

Lazow MA; Fuller C; Lane A; DeWire-Schottmiller MD; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Garcia Lombardi M; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann CJ; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer RJ; Samson Y; Sandler ES; Sevlever G; Tinkle C; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2020, 'NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 295 - 296,

Conference Papers | 2020

Michniewicz F; Saletta F; Rouen J; Ziegler D; Vittorio O, 2020, 'USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 303 - 303,

Conference Papers | 2020

Mondal S; Wong M; Tee A; Ho N; Ziegler DS; Marshall GM; Liu PY; Dinger M; Liu T, 2020, 'The super-enhancer driven long noncoding RNA lncNB promotes neuroblastoma tumorigenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020,

Conference Papers | 2020

Robertson E; Wakefield C; Hetherington K; Ziegler D, 2020, 'Parents' Expectations and Experiences of a Precision Medicine Trial for High-Risk Paediatric Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S47 - S47,

Conference Papers | 2020

Schulte JH; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin M; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Fischer M; Geoerger B, 2020, 'Final analysis of phase I study of ceritinib in pediatric patients with malignancies harboring activated anaplastic lymphoma kinase (ALK).', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020,

Conference Papers | 2020

Sudhaman S; Morgenstern D; Chung J; Nobre L; Alsafwani N; Kelly J; Coblentz A; Edwards M; Bianchi V; Lipman T; Zhang C; Ercan A; Sambira L; Bendel A; Bielack S; Koustenis E; Blumenthal D; Bowers D; Broniscer A; Bronsema A; Carroll S; Chiaravalli S; Cole K; Constantini S; De Mola RL; Dunn G; Frojd C; Gass D; Gauvain K; George B; Hijiya N; Hoffman L; Knipstein J; Laetsch T; Larouche V; Lassaletta A; Luna-Fineman S; Issai VM; Mason G; Mason W; Massimino M; Mordechai O; Opocher E; Oren M; Osborn M; Reddy A; Remke M; Roy S; Sabel M; Samuel D; Schneider K; Sen S; Stearns D; Sumerauer D; Thomas G; Tomboc P; Van Damme A; Wierman M; Winer I; Yen L; Zapotocky M; Ziegler D; Zimmermann S; Dvir R; Rechavi G; Durno C; Aronson M; Taylor M; Dirks P; Pugh T; Shlien A; Hawkins C; Bouffet E; Tabori U, 2020, 'Favorable Outcome in Replication Repair Deficient Hypermutant Tumors to Immune Checkpoint Inhibition: An International RRD Consortium Registry Study', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S19 - S20,

Conference Abstracts | 2020

Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'DDEL-12. NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii286 - iii286,

Conference Papers | 2020

Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 286 - 286,

Conference Abstracts | 2020

Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Nath C; Reynolds P; Tsoli M; Ziegler D, 2020, 'DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii288 - iii288,

Conference Papers | 2020

Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Nath C; Reynolds P; Tsoli M; Ziegler D, 2020, 'HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGS)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 288 - 288,

Conference Abstracts | 2019

Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O'Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2019, 'Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with highrisk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 70 - 71, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019,

Conference Abstracts | 2019

Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Dong-Anh K-Q; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O'Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2019, 'Prevalence and spectrum of germline mutations in children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 42 - 43, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019,

Conference Papers | 2019

Dahl N; Lane A; Bandopadhayay P; Minturn J; Dodgshun A; Parkin S; Shih C-S; Hassall T; Hansford J; Samson Y; Cai L; Leary S; Ma J; Bartels U; Hawkins C; Monje-Diesseroth M; Fisher P; Tsui K; Ziegler D; DeWire-Schottmiller M; Chaney B; Black K; Doughman R; Leach J; Jones B; Fuller C; Fouladi M; Hoffman L, 2019, 'CLINICAL, RADIOLOGICAL, AND HISTO-MOLECULAR CHARACTERISTICS OF DIFFUSE INTRINSIC PONTINE GLIOMA IN PATIENTS WHO SURVIVE LESS THAN 3 MONTHS FROM DIAGNOSIS: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, pp. 76 - 77, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019,

Conference Abstracts | 2019

Duchatel R; Jackson E; Patabendige A; Cain J; Tsoli M; Monje M; Alvaro F; Ziegler D; Dun M, 2019, 'TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, Vol. 21, pp. 68 - 68, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019,

Conference Abstracts | 2019

Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O'Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Dong AKQ; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O'Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2019, 'Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 23 - 24, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019,

Conference Papers | 2019

Li B; Vasiljevic A; Dufour C; Ho B; Hwang E; Gururangan S; Hansford J; Laquerriere A; Delisle M-B; Fangusaro J; Forest F; Sumihito N; Toledano H; Birks D; Fan X; Fouladi M; Gajjar A; Gauchotte G; Hoffman L; Jones C; Loussouarn D; Mokhtari K; Pomeroy S; Rousseau A; Somers G; Taylor M; Ziegler DS; Lu M; Hawkins C; Grundy R; Jouvet A; Bouffet E; Hill DA; Huang A, 2019, 'PINEOBLASTOMA SEGREGATES INTO MOLECULAR SUBTYPES WITH DISTINCT CLINICOPATHOLOGIC FEATURES: REPORT FROM THE RARE BRAIN TUMOUR CONSORTIUM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, AZ, Phoenix, pp. 192 - 192, presented at 24th Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS, AZ, Phoenix, 20 November 2019 - 24 November 2019,

Conference Abstracts | 2019

Mould EV; Lau L; Arndt G; Barahona P; Cowley MJ; Ekert P; Failes T; Fletcher J; Gifford A; Grebert-Wade D; Haber M; Kamili A; Kumar A; Lock RB; Marshall GM; Mayoh C; Norris M; O'Brien T; Quang DAK; Strong P; Sherstyuk A; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler DS; Tyrrell V, 2019, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019,

Conference Abstracts | 2019

Quang DAK; Lau L; Cowley MJ; Ekert PG; Gifford AJ; Haber M; Lock R; Marshall G; Mayoh C; Mould E; Norris M; O'Brien T; Trahair T; Tyrrell V; Ziegler DS, 2019, 'Zero Childhood Cancer: A Comprehensive Precision Medicine Platform for Children and Adolescents with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S504 - S505,

Conference Abstracts | 2019

Robertson E; Wakefield C; Cohn R; Robert B; Donoghoe M; Ziegler D; Fardell J; Mitchell R; O'Brien T, 2019, 'Delta: A Parent and Patient Decision Aid to Support Clinical Trial Decision-Making in Childhood Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S118 - S118,

Conference Abstracts | 2019

Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O'Brien T; Dong AKQ; Cowley M; Ekert P; Ziegler DS, 2019, 'RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRA-TM PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, Vol. 21, pp. 118 - 118, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019,

Conference Abstracts | 2019

Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O’Brien T; Quang DAK; Cowley M; Ekert P; Ziegler DS, 2019, 'THER-23. RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRATED PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 21, pp. ii118 - ii118,

Conference Abstracts | 2019

Vetsch J; Wakefield CE; Warby M; Tucker K; Duve E; Marshall G; Trahair T; O'Brien T; Lau L; Ziegler D, 2019, 'Families' and healthcare professionals' uncertainties in the era of cancer precision medicine: results from PRISM', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, SWEDEN, Gothenburg, Vol. 27, pp. 1172 - 1172, presented at 52nd Conference of the European-Society-of-Human-Genetics (ESHG), SWEDEN, Gothenburg, 15 June 2019 - 18 June 2019,

Conference Presentations | 2018

Anazodo A; Hau P; Hovey E; Nowak A; Pfister S; Hesketh E; Bhadri V; Koh E; Ziegler D, 2018, 'Personalised targeted therapy for adolescent and young adult medulloblastoma patients.', presented at 3rd Global Adolescent and Young Adult Cancer Congress Program, Sheraton Grand Sydney, 04 December 2018 - 06 December 2018,

Conference Papers | 2018

Bartlett A; Cochrane A; Lane A; Yanez-Escorza N; Chaney B; Doughman R; DeWire-Schottmiller M; Goldman S; Warren K; Bandopadhayay P; Foreman N; Shih C-S; Minturn J; Bartels U; Packer R; Nazarian J; Hassall T; Samson Y; Monje-Deisseroth M; Fisher P; Wagner L; Koschmann C; Ziegler D; Kieran M; Hawkins C; White P; Dexheimer P; Hendershot J; Drissi R; Fuller C; Leach J; Jones B; Fouladi M, 2018, 'CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN < 3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, pp. 63 - 63, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018,

Conference Abstracts | 2018

Ekert P; Wong M; Mould E; Gifford A; Norris M; Warby M; Trahair T; Tucker K; Ziegler D; Marshall G; O'Brien T; Haber M; Vanessa T; Cowley M, 2018, 'Zero Childhood Cancer: A Comprehensive Precision Medicine Platform for Children with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 65, pp. S643 - S644,

Conference Abstracts | 2018

Johnson A; Bye A; Ziegler D; Gifford A; Jacobsen E; Cohn R, 2018, 'CRAN-27. PAEDIATRIC EXTRAVENTRICULAR NEUROCYTOMA: A SERIES AND A RARE COMPLICATION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i42 - i42,

Conference Abstracts | 2018

Johnson A; Bye A; Ziegler D; Gifford A; Jacobsen E; Cohn R, 2018, 'PAEDIATRIC EXTRAVENTRICULAR NEUROCYTOMA: A SERIES AND A RARE COMPLICATION', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 42 - 42, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018,

Conference Abstracts | 2018

Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'DIPG-01. TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i49 - i49,

Conference Abstracts | 2018

Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 49 - 49, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018,

Conference Abstracts | 2018

Khan A; Tsoli M; Yu D; Joshi S; Gamble L; Franshaw L; Haber M; Ziegler DS, 2018, 'Targeting the polyamine pathway as a novel therapeutic treatment against diffuse intrinsic pontine glioma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018,

Conference Papers | 2018

Michaiel G; Strother D; Gottardo N; Bartels U; Coltin H; Eisenstat DD; Hukin J; Johnston DL; Wilson B; Zelcer S; Hansford JR; Wells O; Abdelbaki MS; Abu-Arja MH; Cole KA; Dhall G; Fisher PG; Hoffman L; Leary SES; Pickle EEO; Smiley NP; Smith A; Vinitsky A; Vitanza NA; Wright A; Yeo KK; Chow LML; Kirby M; Valvi S; Vanan MI; Wong G; Ziegler D; Bouffet E; Lafay-Cousin L, 2018, 'INTRACRANIAL GROWING TERATOMA SYNDROME (IGTS): AN INTERNATIONAL RETROSPECTIVE STUDY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, pp. 88 - 88, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018,

Conference Abstracts | 2018

Mokgwathi OL; Ziegler DS; Currie B; Tucker K; Gifford AJ, 2018, 'Pleuropulmonary blastoma – Case report of a rare tumour harbouring a DICER1 mutation', in Pathology, Elsevier BV, Vol. 50, pp. S144 - S144,

Conference Abstracts | 2018

Mould E; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Norris M; O'Brien T; Pinese M; Dong AKQ; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler D; Tyrrell V, 2018, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018,

Conference Abstracts | 2018

Robertson E; Wakefield C; Cohn R; O'Brien T; Ziegler D; Fardell J, 2018, 'The development of Delta: a decision aid to help parents considering enroling their child in a paediatric oncology clinical trial', in PSYCHO-ONCOLOGY, WILEY, Vol. 27, pp. 10 - 10,

Conference Abstracts | 2018

Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo A; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien TA, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective.', Hong Kong, presented at International Psycho-Oncology Society, Hong Kong, 31 October 2018 - 02 November 2018

Conference Papers | 2018

Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo AC; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien T, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster)', in Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster), Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, presented at Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, 14 June 2018 - 16 June 2018

Conference Abstracts | 2018

Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin J; Gayevski V; Kumar A; Kaplan W; Ekert P; Franshaw L; Gifford A; Weber M; Rodriguez M; Mayoh C; Cohn R; Arndt G; Lock R; Tyrrell V; Norris M; Haber M; Lau L; Dong AKQ; Wong M; Trahair T; Marshall GM; Cowley MJ; Ziegler DS, 2018, 'Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018,

Conference Abstracts | 2018

Vetsch J; Wakefield CE; Tucker K; Warby M; Techakesari P; Marshall G; Trahair TN; O'Brien T; Marron JM; Lau L; Tyrell V; Ziegler D, 2018, 'The PRISM-IMPACT study: What are the hopes and expectations of families and health care professionals enrolling in a personalised medicine trial for high risk childhood cancers?', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, ITALY, Milan, Vol. 27, pp. 690 - 691, presented at 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), ITALY, Milan, 16 June 2018 - 19 June 2018,

Conference Abstracts | 2018

Wakefield CE; Vetsch J; Tucker KM; Warby M; O'Brien T; Techakesari P; Glenn M; Trahair TN; Marron JM; Lau L; Tyrell V; Ziegler D, 2018, 'Families' and Healthcare Professionals' Hopes and Expectations Participating in a Precision Medicine Trial for Children with High-Risk Cancer: The PRISM-Impact Study', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 65, pp. S62 - S62,

Conference Papers | 2018

Xiao L; Murray J; Ehteda A; Somers C; Mayoh C; Gamble L; Pandher R; Tsoli M; Eden G; Allan S; Sarraf S; Kosciolek A; Ziegler D; Henderson M; Issaeva N; Gurova K; Gudkov A; Haber M; Norris M, 2018, 'Chromatin destabilization by CBL0137 and panobinostat leads to complete tumour regression of childhood neuroblastoma in immunocompetent transgenic mice', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, IRELAND, Dublin, pp. E25 - E25, presented at 30th EORTC-NCI-AACR Symposium, IRELAND, Dublin, 13 November 2018 - 16 November 2018,

Conference Abstracts | 2018

Ziegler D; Tsoli M; Tyre V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 67 - 67, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018,

Conference Abstracts | 2018

Ziegler D; Tsoli M; Tyrell V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'EAPH-09. POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i67 - i67,

Conference Papers | 2017

Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017,

Conference Abstracts | 2017

Ehteda A; Kankean A; Chitranjan A; Tsoli M; Liu J; Shen H; Franshaw L; Joshi S; Chang C; Ager E; Ziegler DS, 2017, 'DIPG-09. TRX-E-009-1 IS A��NOVEL AND A��POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6,

Conference Papers | 2017

Ehteda A; Kankean A; Chitranjan A; Tsoli M; Liu J; Shen H; Franshaw L; Joshi S; Chang C; Ager E; Ziegler DS, 2017, 'TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 6 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017,

Conference Abstracts | 2017

Franshaw L; Chang C; Joshi S; Ehteda A; Tsoli M; Ziegler D, 2017, 'DIPG-07. INDUCING DNA LETHALITY THROUGH POLO-LIKE KINASE 1 INHIBITION: A��NOVEL THERAPEUTIC APPROACH IN DIPG', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6,

Conference Papers | 2017

Franshaw L; Chang C; Joshi S; Ehteda A; Tsoli M; Ziegler D, 2017, 'INDUCING DNA LETHALITY THROUGH POLO-LIKE KINASE 1 INHIBITION: A NOVEL THERAPEUTIC APPROACH IN DIPG', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 6 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017,

Conference Abstracts | 2017

Franshaw L; Tsoli M; Byrne J; Sivarajasingam S; Norris M; Marshall G; Ziegler D, 2017, 'TRTH-05. PREDICTORS OF SUCCESS OF PHASE 2 PAEDIATRIC ONCOLOGY CLINICAL TRIALS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv52 - iv52,

Conference Abstracts | 2017

Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017,

Conference Abstracts | 2017

Shen H; Chang C; Joshi S; Liu J; Tsoli M; Hau E; Ziegler D, 2017, 'DIPG-02. RADIOSENSITIVITY OF DIPG CELLS IS ENHANCED BY TARGETING GLUCOSE METABOLISM IN VITRO AND IN VIVO', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5,

Conference Papers | 2017

Shen H; Chang C; Joshi S; Liu J; Tsoli M; Hau E; Ziegler D, 2017, 'RADIOSENSITIVITY OF DIPG CELLS IS ENHANCED BY TARGETING GLUCOSE METABOLISM IN VITRO AND IN VIVO', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 5 - 5, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017,

Conference Papers | 2017

Tsoli M; Lapin D; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'COMBINED TARGETING OF CALCIUM SIGNALLING AND RTK/PI3K PATHWAY IS A NOVEL THERAPEUTIC APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 5 - 5, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017,

Conference Abstracts | 2017

Tsoli M; Lapin D; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'DIPG-04. COMBINED TARGETING OF CALCIUM SIGNALLING AND RTK/PI3K PATHWAY IS A��NOVEL THERAPEUTIC APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5,

Conference Abstracts | 2017

Tsoli M; Yeung N; Valvi S; Joshi S; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, Vol. 19, pp. 5 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017,

Conference Abstracts | 2017

Tsoli M; Yeung N; Valvi S; Joshi S; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'DIPG-05. COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A��POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv6,

Conference Papers | 2016

Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 51 - 51, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016,

Conference Abstracts | 2016

Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'HG-20COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-oncology, Vol. 18, pp. iii51 - iii51

Conference Abstracts | 2016

Fardell J; Donovan L; Wakefield C; Russell V; Mitchell R; O'Brien T; Ziegler D; Glenn M; Cohn R, 2016, 'Outcomes of Bereaved Parents Whose Child Did or Did not Participate in An Early Phase Clinical Trial', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S62 - S62,

Conference Abstracts | 2016

Robertson E; Fardell J; O'Brien T; Cohn R; Mitchell R; Drew D; Ziegler D; Marshall G; Wakefield C, 2016, 'Treatment Decision Making for Young People with Cancer and Their Parents', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S232 - S232,

Conference Papers | 2016

Shen H; Tsoli M; Chang C; Chitranjan A; Liu J; Hau E; Kankean A; Ehteda A; Franshaw L; Valvi S; Ziegler D, 2016, 'DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 48 - 48, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016,

Conference Abstracts | 2016

Shen H; Tsoli M; Chang C; Chitranjan A; Liu J; Hau E; Kankean A; Ehteda A; Franshaw L; Valvi S; Ziegler D, 2016, 'HG-04DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii48.3 - iii48,

Conference Papers | 2016

Tsoli M; Chang C; Shen H; Liu J; Chintranjan A; Franshaw L; Dilda P; Carcaboso AM; Hogg P; Ziegler D, 2016, 'COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 51 - 51, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016,

Conference Abstracts | 2016

Tsoli M; Chang C; Shen H; Liu J; Chintranjan A; Franshaw L; Dilda P; Carcaboso AM; Hogg P; Ziegler D, 2016, 'HG-19COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii51.3 - iii51,

Conference Papers | 2016

Valvi S; Tsoli M; Chitranjan A; Shen H; Chang C; Kankean A; Ehteda A; Franshaw L; Liu J; Ziegler D, 2016, 'FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 52 - 53, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016,

Conference Abstracts | 2016

Valvi S; Tsoli M; Chitranjan A; Shen H; Chang C; Kankean A; Ehteda A; Franshaw L; Liu J; Ziegler D, 2016, 'HG-25FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii52.5 - iii53,

Conference Papers | 2015

Carter DR; Murray J; Cheung BB; Kalla H; Gamble L; Tsang J; Sutton S; Koach J; Syed S; Gifford A; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Purmal A; Ziegler D; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'MYCN and is a therapeutic target in neuroblastoma', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, La Jolla, presented at AACR Special Conference on Myc - From Biology to Therapy, CA, La Jolla, 07 January 2015 - 10 January 2015,

Conference Abstracts | 2015

Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Henderson MJ; Middlemass S; Carter D; Tsoli M; Ehteda A; Simon S; Oberthuer A; Fischer M; Gurova K; Burkhart C; Purmal A; Lock RB; Ziegler D; Marshall GM; Gudkov AV; Norris MD, 2015, 'The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015,

Conference Abstracts | 2015

Kankean A; Ehteda A; Chitranjan A; Tsoli M; Ager E; Ziegler D, 2015, 'BT-09 * TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii5 - iii5,

Conference Papers | 2015

Kankean A; Ehteda A; Chitranjan A; Tsoli M; Ager E; Ziegler D, 2015, 'TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, pp. 5 - 5, presented at 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Diego, 07 May 2015 - 08 May 2015,

Conference Abstracts | 2015

Kankean A; Tsoli M; Tsang J; Chitranjan A; Maleki S; McDonald K; Ziegler D, 2015, 'HG-16 * THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii14 - iii14,

Conference Papers | 2015

Kankean A; Tsoli M; Tsang J; Chitranjan A; Maleki S; McDonald K; Ziegler D, 2015, 'THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, pp. 14 - 14, presented at 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Diego, 07 May 2015 - 08 May 2015,

Conference Papers | 2015

Vedi A; Mitchell R; Oswald C; Marshall GM; Trahair T; Ziegler DS, 2015, 'Increased Use of Allogeneic Transplant in CR2 Improves the Outcome for Children with Acute Myeloid Leukaemia', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, presented at 57th Annual Meeting of the American-Society-of-Hematology, FL, Orlando, 05 December 2015 - 08 December 2015,

Conference Papers | 2015

Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2015, 'Molecular profiling of relapsed childhood cancer', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, UT, Salt Lake, presented at Meeting of the American-Association-for-Cancer-Research (AACR) Precision Medicine Series - Integrating Clinical Genomics and Cancer Therapy, UT, Salt Lake, 13 June 2015 - 16 June 2015,

Conference Papers | 2014

Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, European Org Res & Treatment Canc, Barcelona, pp. 135 - 135, presented at 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, SPAIN, European Org Res & Treatment Canc, Barcelona, 18 November 2014 - 21 November 2014,

Conference Papers | 2014

Tsoli M; Vanniasinghe A; Luk P; Dilda P; Haber M; Hogg P; Ziegler D, 2014, 'TARGETING MITOCHONDRIA AND CELL METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, SINGAPORE, Singapore, pp. 47 - 47, presented at 16th International Symposium on Pediatric Neuro-Oncology (ISPNO), SINGAPORE, Singapore, 28 June 2014 - 02 July 2014,

Conference Abstracts | 2013

Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2013, 'beta III-tubulin in glioblastoma: An emerging multifactorial survival factor role in chemotherapy response and tumor formation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, Vol. 73, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013,

Conference Papers | 2013

Norris MD; Gamble LD; Murray J; Purqato S; Miiazzo G; Ashton LJ; Oberthuer A; London WB; Hogarty MD; Fischer M; Ziegler D; Marshall GM; Perini G; Haber M, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013,

Conference Papers | 2013

Tsoli M; Luk P; Dilda P; Hogg P; Haber M; Ziegler D, 2013, 'TARGETING MITOCHONDRIA AND METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, FL, Fort Lauderdale, pp. 21 - 21, presented at 2nd Annual Pediatric Neuro-Oncology Basic and Translational Research Conference, FL, Fort Lauderdale, 16 May 2013 - 17 May 2013,

Conference Papers | 2012

Lee H; Ziegler D, 2012, 'LONGER DURATION OF SYMPTOMS AT DIAGNOSIS IS AN INDEPENDENT PROGNOSTIC FACTOR IN PEDIATRIC DIFFUSE PONTINE INTRINSIC GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CANADA, Toronto, pp. 29 - 29, presented at 15th International Symposium on Pediatric Neuro-Oncology (ISPNO), CANADA, Toronto, 24 June 2012 - 27 June 2012,

Conference Abstracts | 2012

Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2012, 'beta III-TUBULIN AND GLIOBLASTOMA: ROLE IN DRUG RESISTANCE AND TUMOURIGENESIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 8, pp. 303 - 304,

Conference Papers | 2011

Mateos M; O'Brien TA; Gabriel M; Oswald C; Cohn RJ; Russell S; Ziegler DS; Barbaric D; Vowels M; Maurice L; Senner A; Marshall G; Trahair T, 2011, 'IMPROVED SURVIVAL FOLLOWING ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) FOR PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL): A RETROSPECTIVE REVIEW FROM 1984-2009', in PEDIATRIC BLOOD & CANCER, WILEY PERIODICALS, INC, pp. 817 - 817,

Conference Papers | 2010

Smee RI; Cohn R; Ziegler D; Kwok B; Johnston H; Bye A; Andrews I; Stening W, 2010, 'A RETROSPECTIVE REVIEW OF CHILDREN TREATED AT THE SYDNEY CHILDREN'S HOSPITAL/PRINCE OF WALES HOSPITAL', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, AUSTRIA, Vienna, pp. II69 - II70, presented at 14th International Symposium on Pediatric Neuro-Oncology, AUSTRIA, Vienna, 20 June 2010 - 23 June 2010,

Conference Papers | 2004

Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald C; Mrongovius R; White F, 2004, 'Efficacy of high-dose cyclophosphamide with etoposide and vinchistine ("VETOPEC") in very high-risk paediatric brain tumours', in NEURO-ONCOLOGY, DUKE UNIV PRESS, MA, Boston, pp. 469 - 469, presented at 11th International Symposium on Pediatric Neuro-Oncology, MA, Boston, 13 June 2004 - 16 June 2004,

Preprints |

Crothers AL; Haeusler GM; Slavin MA; Babl FE; Mechinaud F; Phillips R; Tapp H; Padhye B; Ziegler DS; Clark J; Walwyn T; Super L; Alvaro F; Thursky K; Lourenco RDA, Examining Health-Related Quality of Life in Pediatric Cancer Patients with Febrile Neutropenia: Factors Predicting for Poor Recovery in Children and the Parents, ,

Prof Ziegler's research focused on the preclinical and clinical development of novel therapies for paediatric cancer including high risk brain tumours. Prof Ziegler has established an Australian translational research program to develop novel therapies for children with cancer, and has led several national and international early phase clinical trials. He is chair of a national study of precision medicine for high risk childhood cancers through the ZERO childhood cancer program.

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