Dr Kurosh Parsi
Undergraduate Degree
Bachelor of Medicine, Bachelor of Surgery (MBBS)
The University of Sydney
1993
Postgraduate Degrees
Master of Science (Medicine)
Thesis: Travellers’ Venous Thromboembolism
Supervisor: Professor Reginald Lord
Co-supervisors: Dr Michael McGrath, Professor David Ma
Departments of Vascular Surgery, Vascular Medicine and Haematology
St. Vincent’s Hospital
University of New South Wales (UNSW)
2001
Ph D
Thesis: Interaction of Detergent Sclerosants with Coagulation, Antithrombotic and Fibrinolytic Mechanisms
Supervisor: Dr Joanne Joseph
Co-supervisors: Professor David Ma, Professor Ken Myers
Haematology Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
2011
Master of International Law (LLM)
University of Salford (United Kingdom)
2021
Fellowships
Australasian College of Phlebology
2000 FACP (Foundation Fellowship)
Australasian College of Dermatologists
2004 FACD
Australasian College of Legal Medicine
2022 FACLM
Professional Memberships
- American Venous Lymphatic Society(AVLS)
- American Venous Forum (AVF)
- Asia Pacific Society for Thrombosis and Haemostasis (APSTH)
- Australian Society for Thrombosis and Haemostasis (ASTH)
- Australasian Society for Ultrasound in Medicine (ASUM)
- Australian Vascular Anomalies Network
- Canadian Society of Phlebology (CSP)
- European Society for Vascular Surgery (ESVS)
- International Society for Fibrinolysis and Proteolysis (ISFP)
- International Society for the Study of Vascular Anomalies (ISSVA)
- International Society for Thrombosis and Hemostasis (ISTH)
Professor Kurosh Parsi MBBS, MSc (Med), PhD, LLM, FACD, FACP, FACLM is a dermatologist, and specialist. Prof. Parsi is the Head of Department of Dermatology, St. Vincent’s Hospital, Sydney and Program Head, Dermatology, Phlebology and Fluid Mechanics Research Laboratory, St. Vincent’s Centre for Applied Medical Research. He served as Staff Specialist in Dermatology and Vascular Anomalies, Sydney Children’s Hospital for 10 years. Professor Parsi sub-specializes in and vascular dermatology. Prof Parsi is a fellow of the Australasian College of Dermatologists (FACD), Australasian College of Phlebology (FACP) and Australasian College of Legal Medicine (FACLM).
Prof. Parsi is a medical graduate of the University of Sydney (MBBS). He obtained his Master of Science in Medicine (MSc) followed by a PhD in the field of thrombosis, haemostasis and fibrinolysis from the University of New South Wales (UNSW). He then completed a Master of International Law (LLM) from the University of Salford, Manchester.
Prof. Parsi is a conjoint Professor of Medicine at UNSW and has served as an Adjunct Professor of Fluid Mechanics at the University of Sydney, School of Mechanical and Mechatronic Engineering.
Professor Parsi’s basic science research has focused on physico-chemical and fluid mechanics of sclerosant foams and the interaction of detergent sclerosants with coagulation, antithrombotic and fibrinolytic mechanisms. His clinical research in phlebology has focused on deep vein sclerosis and sclerothrombus. His research in dermatology has been on dermatological conditions with a vascular aetiology including , and reticulate eruptions.
Professor Parsi served the Australasian College of Phlebology (ACP) as President (2007-2017) and was the convener of the Annual Scientific Meetings (2007-2017) and the World Congress of Phlebology (Melbourne, Australia; 4-8 February 2018).
Prof. Parsi is the Immediate Past President of the International Union of Phlebology (UIP) and prior to that served as Vice President (2009-2013), Treasurer (2013-2017) and President-elect (2018-2019).
- Publications
- Media
- Grants
- Awards
- Research Activities
- Engagement
- Teaching and Supervision
|
2008 |
AUD 180,000 |
BODYFLOW INTERNATIONAL |
|
2011 |
USD 50,000 |
AMERICAN COLLLEGE OF PHLEBOLOGY |
|
2012 |
AUD 20,698 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
|
2013 |
AUD 24,396 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
|
2013 |
EUR 10,000 |
KREUSSLER PHARMA, GERMANY |
|
2014 |
AUD 35,329 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
|
2015 |
AUD 48,212 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
|
2015 |
AUD 55,000 |
GALDERMA AUSTRALIA |
|
2015 |
USD 50,000 |
AMERICAN COLLLEGE OF PHLEBOLOGY |
|
2016 |
AUD 55,000 |
GALDERMA AUSTRALIA |
|
2017 |
AUD 49,000 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
|
2018 |
AUD 83,000 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
|
2019 |
AUD 55,000 |
ACADEMY OF PHLEBOLOGY AND LONGEVITY STUDIES |
GOLD Medal Recipient
Australasian College of Phlebology (2018)
for Major Contributions to Phlebology on an International Level
Visiting Professor
Royal Society of Medicine (UK, 2019)
Member of Honour
2013 Argentinian Society of Phlebology and Lymphology
2018 French Society of Phlebology
We conduct most of our work from Dermatology, Phlebology and Fluid Mechanics Research Laboratory, Level 8,St. Vincent's Centre for Applied Medical Research.
In phlebology, we have investigated sclerosing agents and their interaction with blood components, thrombotic and antithrombotic mechanisms.
My interest in basic science research has focussed on the biological effects sclerosing agents.
In fluid mechanics, our research has focussed on physics and rheology of sclerosing foams.
In vascular dermatology, we have investigated conditions such as pigmented purpuric dermatosis and vascular malformations.
COMPLETED PROJECTS
1998-1999 Imiquimod Trial in Treatment of Basal Cell Carcinomas
Co-investigator Department of Dermatology
Liverpool hospital
Publication:
Shumack S, Robinson J, Kossard S, Golitz L, Greenway H, Schroeter A, Andres K, Amies M, Owens M. Efficacy of topical 5% imiquimod cream for the treatment of nodular basal cell carcinoma: comparison of dosing regimens. Arch Dermatol. 2002 Sep;138(9):1165-71.
1999-2000 Travelers Venous Thromboembolism
Principal Investigator Master of Science (Medicine)
Departments of Vascular Surgery and Vascular Medicine
St. Vincent’s Hospital
University of New South Wales (UNSW)
Publications:
Parsi K, McGrath M, Lord R. Traveller's Venous Thromboembolism. Cardiovascular
Surgery 2001;9: 157-8.
1999 Acitretin in Chemoprevention of Actinic Keratoses and
Study Design Squamous Cell Carcinomas in Post-operative Cardiac Transplant Patients
Skin & Cancer Foundation Australia
Department of Cardiothoracic Surgery
St Vincent’s Hospital
University of New South Wales (UNSW)
2004-2011 Interaction of Detergent Sclerosants with Coagulation,
Principal Investigator Antithrombotic and Fibrinolytic Mechanisms
Doctor of Philosophy
Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
2004-2006 Electrostimulation in Prevention of Deep Vein
Principal Investigator Thrombosis
Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
2004 Microbiology of Rosacea
Co-Investigator Department of Dermatology
St. Vincent’s Hospital
University of New South Wales (UNSW)
2004-2007 Sclerosants, Clotting Factors, Platelets and Microparticles
Principal Investigator Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Parsi K, Exner T, Connor DE, Ma DDF, Joseph JE. In vitro Effects of Detergent Sclerosants on Coagulation, Platelets and Microparticles. Eur J Vasc Endovasc Surg. 2007;34:731-740.
2006-2019
Principal Investigator The Role of D-dimer in the Differential Diagnosisof Deep Vein Thrombosis and Deep Vein Sclerosis
Haematology Research Lab, St. Vincent’s Hospital
Dermatology, Phlebology and Fluid Mechanics Research Lab,
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
This is a prospective study of a cohort of more than 2000 patients undergoing sclerotherapy to assess the role of D-dimer in the evaluation of post-sclerotherapy deep vein occlusion.
Publication:
Parsi K, Panozzo B, Bull A, Yang A, Kang M, Parsi Y, Connor DE. Deep Vein Sclerosis (DVS) Following Sclerotherapy: Ultrasonic and D-Dimer Criteria. Phlebology. 2019 Submitted.
2007-2008 The Lytic Effects of Detergent Sclerosants
Principal Investigator Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Parsi K, Exner T, Connor DE, Herbert A, Ma DDF, Joseph JE. The Lytic Effects of Detergent Sclerosants on Erythrocytes, Platelets, Endothelial Cells and Microparticles are Attenuated by Albumin and other Plasma Components In vitro. Eur J Vasc Endovasc Surg. 2008;36:216-23.
2007-2011 Prevention of Venous Gas Embolism in Foam Sclerotherapy
Principal Investigator Phlebology Research Lab, Sydney Skin & Vein Clinic
Publication:
Parsi K. Venous Gas Embolism During Foam Sclerotherapy of Saphenous Veins Despite Recommended Treatment Modifications. Phlebology 2011;4:140-147.
2008-2009 Sclerosants and Antithrombotic Mechanisms
Principal Investigator Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Parsi K, Exner T, Low J, Ma DDF, Joseph JE. In Vitro Effects of Detergent Sclerosants on Antithrombotic Mechanisms. Eur J Vasc Endovasc Surg. 2009;38:220-8.
2009-2010 Sclerosants and Fibrinolytic Mechanisms
Principal Investigator Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Parsi K, Exner T, Ma DDF, Joseph JE. In vitro Effects of Detergent Sclerosants on Fibrinolytic Enzymes and Inhibitors. Thromb Res. 2010;126:328-36.
2009-2010 Sclerosants, Clot Formation and Fibrinolysis
Principal Investigator Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Parsi K, Exner T, Low J, Ma DDF, Joseph JE. In vitro Effects of Detergent Sclerosants on Clot Formation and Lysis. Eur J Vasc Endovasc Surg. 2010;41:267-77.
2009-2010 Fluid Mechanics of Foam Sclerosants
Co-Investigator School of Aerospace, Mechanical & Mechatronic Engineering
and Associate Supervisor University of Sydney (USYD)
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
This study was a collaboration with the School of Fluid Mechanics, Faculty of Engineering, the University of Sydney and formed an Honours project for Biomedical student Evan Cameron.
Publication:
Cameron E, Chen T, Connor DE, Behnia M, Parsi K. Sclerosant Foam Structure and Stability is Strongly Influenced by Liquid Air Fraction. Eur J Vasc Endovasc Surg. 2013; 46:488-94.
2010-2011 Sclerosants and Platelet Activation and Aggregation
Principal Investigator Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Parsi K, Pilotelle A, Conner DE, Exner T, Lowe J, Ma DDF, Joseph JE. Low Concentration Detergent Sclerosants Induce Platelet Activation but Inhibit Aggregation due to Suppression of GPIIb/IIIa Activation in vitro. Thromb Haemost. 2012; 130:472-8.
2008-2013 In vivo Effects of Detergent Sclerosants on Coagulation,
Principal Investigator Antithrombotic and Fibrinolytic Mechanisms
Haematology Research Lab, St. Vincent’s Hospital
Phlebology Research Lab, Sydney Skin & Vein Clinic
University of New South Wales (UNSW)
Publication:
Connor D, Joseph J, Exner T, Ma D, Parsi K. Infusion of foam sclerosants results in a distance-dependent procoagulant activity, haemoconcentration and elevation of D-dimer levels. Phlebology 2013; Sep 3.
2011-2014 In vitro Effects of Detergent Sclerosants on Blood Cells,
Principal Investigator Inflammation and Angiogenesis
Haematology Research Lab, St. Vincent’s Centre for Applied Medical Research
Dermatology, Phlebology and Fluid Mechanics Research Lab,
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Publication:
Cooley-Andrade O, Jothidas A, Goh WX, Connor DE, Parsi K. Low-concentration detergent sclerosants stimulate white blood cells and release proinflammatory and proangiogenic cytokines invitro. J Vasc Surg Venous Lymphat Disord. 2014 Oct;2(4):433-40. doi: 10.1016/j.jvsv.2014.02.005
2011- Computational Fluid Dynamics of Foam Sclerosants
Co-Investigator School of Aerospace, Mechanical & Mechatronic Engineering
and Primary Supervisor University of Sydney (USYD)
Dermatology, Phlebology and Fluid Mechanics Research Lab,
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
This study was a collaboration with the School of Fluid Mechanics, Faculty of Engineering, University of Sydney.
Wong K, Chen T, Connor DE, Behnia M, Parsi K. Computational Fluid Dynamics of Liquid and Foam Sclerosant Injection in a Vein Model. Applied Mechanics and Materials 2013; 553, 293-298
2012- Apoptotic Effects of Detergent Sclerosants
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Publications:
Cooley-Andrade O, Connor DE, Ma DDF, Weisel JW, Parsi K. Morphological changes in vascular and circulating blood cells following exposure to detergent sclerosants. Phlebology / Venous Forum of the Royal Society of Medicine 02/2015; DOI:10.1177/0268355515573686
Cooley-Andrade O, Cheung K, Chew AN, Connor DE, Parsi K. Detergent sclerosants at sub-lytic concentrations induce endothelial cell apoptosis through a caspase dependent pathway. Apoptosis. 2016 Jul;21(7):836-45. doi:10.1007/s10495-016-1252-3.
Cooley-Andrade O, Goh WX, Connor DE, Ma DD, Parsi K. Detergent Sclerosants Stimulate Leukocyte Apoptosis and Oncosis. Eur J Vasc Endovasc Surg. 2016 Jun;51(6):846-56. doi: 10.1016/j.ejvs.2016.03.008.
Yang A, Dhanji P, Wijaya M, Chen X, Cooley-Andrade O, Connor DE, Parsi K. Detergent Sclerosants cause apoptosis of squamous cell carcinoma cells in vitro. J Inv Derm 2019. Submitted.
2014- Endothelial Cell and Platelet Binding and Activation
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Publication:
Connor DE, Cheung K, Gerbelli J, Chew AN, Goonawardhana D, Parsi K. Low Concentration Detergent Sclerosants Induce Endothelial Activation in vitro. Eur J Vasc Endovasc Surg. 2019. Submitted.
CURRENT and ONGOING PROJECTS
2007- Haemostatic Abnormalities in Pigmented Purpuric Dermatoses
Principal Investigator Department of Dermatology, St. Vincent’s Hospital
Haematology Research Lab, St. Vincent’s Hospital
Dermatology, Phlebology and Fluid Mechanics Research Lab,
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Aims:
To investigate the underlying haemostatic abnormalities in patients with pigmented purpuric dermatoses.
2013- Identification and Characterisation of Sclerocoagulum
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Aims:
To investigate the molecular structure of sclerothrombus and how it differs from a fibrin thrombus. In collaboration with Prof. John Weisel, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
2015- The Role of Tumescent Anaesthesia in the Management of Arteriovenous Malformations
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Aims:
To investigate the role of tumescent anaesthesia in vessel wall approximation during endovenous ablative procedures.
2016- Compression Stockings and Compression of Superficial Veins
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Aims:
To investigate whether compression stockings actually compress superficial veins.
Publication:
Yang A, Yasaman B, Parsi Y, Kang M, Connor D, Parsi K. Two layers of graduated compression stockings can reduce healthy saphenous vein diameters in the standing position. Phlebology. 2019 Feb 10:268355519828871. doi: 10.1177/0268355519828871.
2017- Restless Leg Syndrome
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Aims:
To investigate the contribution of venous disease to the pathophysiology of restless leg syndrome.
2018- Vascular Aetiology of Reticulate Eruptions
Primary Supervisor Dermatology, Phlebology and Fluid Mechanics Research Laboratory
St. Vincent’s Centre for Applied Medical Research
University of New South Wales (UNSW)
Aims: To investigate the underlying vascular abnormalities in the pathogenesis of reticulate eruptions.
AUSTRALASIAN COLLEGE OF PHLEBOLOGY
LEAD AUTHOR, CYANOACRYLATE GLUE IN PERIPHERAL VEINS CONSENSUS, 2019
MEMBER, ULTRASOUND GUIDED SCLEROTHERAPY, 2016
MEMBER, DIRECT VISION SCLEROTHERAPY, 2016
MEMBER, ENDOVENOUS LASER ABLATION STANDARDS , 2010
MEMBER, ULTRASOUND GUIDED SCLEROTHERAPY, 2010
MEMBER, DIRECT VISION SCLEROTHERAPY, 2010
UIP INTERNATIONAL CONSENSUS GUIDELINES
Lead Author, POST-THROMBOTIC FIBROSIS, 2019
Lead Author, VENOUS MAPPING CONSENSUS COMMITTEE, 2019
Lead Author, CONTRAINDICATION OF SCLEROTHERAPY CONSENSUS COMMITTEE, 2017
MEMBER, FOAM SCLEROTHERAPY CONSENSUS COMMITTEE, 2013
MEMBER, VENOUS ULCERS CONSENSUS COMMITTEE, 2013
MEMBER, CONGENITAL VASCULAR MALFORMATION DIAGNOSTIC COMMITTEE, 2013
MEMBER, VENOUS HAEMODYNAMICS CONSENSUS COMMITTEE, 2012
Lead Author, Phlebology Curriculum, 2009
MEMBER, VENOUS MALFORMATIONS CONSENSUS COMMITTEE, 2008
INTERNATIONAL UNION OF ANGIOLOGY (IUA) CONSENSUS GUIDELINES
MEMBER, ARTERIO-VENOUS MALFORMATIONS CONSENSUS COMMITTEE, 2010
My Research Supervision
PhD, Masters, Biomed and ILP students.