Professor Shan Rajendra

Phone

02-97228814

E-mail

Shan.Rajendra@health.nsw.gov.au

Location

Liverpool NSW

Journal articles | 2023

Rajendra S; Sharma P, 2023, 'Causal Link of Human Papillomavirus in Barrett Esophagus and Adenocarcinoma: Are We There Yet?', Cancers, 15,

Journal articles | 2022

Rajendra S, 2022, 'Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline', American Journal of Gastroenterology, 117, pp. 1880,

Journal articles | 2021

Sundaram S; Olson S; Sharma P; Rajendra S, 2021, 'A review of the impact of the covid-19 pandemic on colorectal cancer screening: Implications and solutions', Pathogens, 10,

Journal articles | 2020

Parameshwaran K; Sharma P; Rajendra S; Stelzer-Braid S; Xuan W; Rawlinson WD, 2020, 'Circulating human papillomavirus DNA detection in Barrett's dysplasia and esophageal adenocarcinoma', Diseases of the Esophagus, 32,

Journal articles | 2020

Rajendra S; Pavey D; McKay O; Merrett N; Gautam SD, 2020, 'Human papillomavirus infection in esophageal squamous cell carcinoma and esophageal adenocarcinoma: a concise review', Annals of the New York Academy of Sciences, 1482, pp. 36 - 48,

Journal articles | 2020

Rajendra S; Sharma P; Gautam SD; Saxena M; Kapur A; Sharma P; Merrett N; Yang T; Santos LD; Pavey D; Sharaiha O; McKay O; Dixson H; Xuan W, 2020, 'Association of Biomarkers for Human Papillomavirus with Survival among Adults with Barrett High-grade Dysplasia and Esophageal Adenocarcinoma', JAMA Network Open, 3,

Journal articles | 2020

Rajendra S; Sharma P; gautum S; saxena M; Kapur A; Merrett N; Yang T; Santos L; Pavey D; Dixson H; McKay O; Xuan W, 2020, 'Association of Biomarkers for Human Papillomavirus With Survival Among Adults With Barrett High-grade Dysplasia and Esophageal Adenocarcinoma', JAMA Network Open,

Journal articles | 2020

Rajendra S; Xuan W; Hufnagel K; Sharma P; Pavey D; Alhajjiri N; Rattan A; Wang B, 2020, 'Antibodies against human papillomavirus proteins in Barrett's dysplasia and intramucosal esophageal adenocarcinoma', Annals of the New York Academy of Sciences, 1470, pp. 44 - 56,

Journal articles | 2020

Sharma P; Gautam SD; Rajendra S, 2020, 'Importance of investigating high-risk human papillomavirus in lymph node metastasis of esophageal adenocarcinoma', World Journal of Gastroenterology, 26, pp. 2729 - 2739,

Journal articles | 2019

Rajendra S; Sharma P, 2019, 'Transforming human papillomavirus infection and the esophageal transformation zone: Prime time for total excision/ablative therapy?', Diseases of the Esophagus, 32,

Journal articles | 2018

El-Zimaity H; Di Pilato V; Ringressi MN; Brcic I; Rajendra S; Langer R; Dislich B; Tripathi M; Guindi M; Riddell R, 2018, 'Risk factors for esophageal cancer: Emphasis on infectious agents', Annals of the New York Academy of Sciences, 1434, pp. 319 - 332,

Journal articles | 2018

Rajendra S; Wei X; Merrett N, 2018, 'Survival Rates for Patients With Barrett High-grade Dysplasia and Esophageal Adenocarcinoma With or Without Human Papillomavirus Infection', JAMA Network Open., JAMA Network Open. 2018;1(4):e181054.,

Journal articles | 2018

Wong MYW; Wang B; Yang A; Khor A; Xuan W; Rajendra S, 2018, 'Human papillomavirus exposure and sexual behavior are significant risk factors for Barrett's dysplasia/esophageal adenocarcinoma', Diseases of the Esophagus, 31,

Journal articles | 2017

Rajendra S; Sharma P, 2017, 'Barrett Esophagus and Intramucosal Esophageal Adenocarcinoma', Hematology/Oncology Clinics of North America, 31, pp. 409 - 426,

Journal articles | 2017

Rajendra S; Yang T; Xuan W; Sharma P; Pavey D; Lee CS; Le S; Collins J; Wang B, 2017, 'Active human papillomavirus involvement in Barrett's dysplasia and oesophageal adenocarcinoma is characterized by wild-type p53 and aberrations of the retinoblastoma protein pathway', International Journal of Cancer, 141, pp. 2037 - 2049,

Journal articles | 2016

Rajendra S; Wang B; Merrett N; Sharma P; Humphris J; Lee HC; Wu J, 2016, 'Genomic analysis of HPV-positive versus HPV-negative oesophageal adenocarcinoma identifies a differential mutational landscape', Journal of Medical Genetics, 53, pp. 227 - 231,

Journal articles | 2016

Rajendra S; Wang B, 2016, 'Human papillomavirus not detected in esophageal adenocarcinoma tumor specimens-Letter', Cancer Epidemiology, 43, pp. 119,

Journal articles | 2015

Rajendra S; Wang B; Pavey D; Sharma P; Yang T; Lee CS; Gupta N; Ball MJ; Gill RS; Wu. X, 2015, 'Persistence of Human Papillomavirus, Overexpression of p53, and Outcomes of Patients After Endoscopic Ablation of Barrett's Esophagus', Clinical Gastroenterology and Hepatology,

Journal articles | 2015

Rajendra S, 2015, 'Barrett's oesophagus: Can meaningful screening and surveillance guidelines be formulated based on new data and rejigging the old paradigm?', Best Practice and Research: Clinical Gastroenterology, 29, pp. 65 - 75,

Journal articles | 2015

Whiteman DC; Appleyard M; Bahin FF; Bobryshev YV; Bourke MJ; Brown I; Chung A; Clouston A; Dickins E; Emery J; Eslick GD; Gordon LG; Grimpen F; Hebbard G; Holliday L; Hourigan LF; Kendall BJ; Lee EYT; Levert-Mignon A; Lord RV; Lord SJ; Maule D; Moss A; Norton I; Olver I; Pavey D; Raftopoulos S; Rajendra S; Schoeman M; Singh R; Sitas F; Smithers BM; Taylor AC; Thomas ML; Thomson I; To H; von Dincklage J; Vuletich C; Watson DI; Yusoff IF, 2015, 'Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma', Journal of Gastroenterology and Hepatology (Australia), 30, pp. 804 - 820,

Journal articles | 2014

Rajendra S; Sharma P, 2014, 'Barrett's Esophagus.', Curr Treat Options Gastroenterol, 12, pp. 169 - 182,

Journal articles | 2013

Rajendra S; Wang B; Snow ET; Sharma P; Pavey DA; Merrett ND; Ball M; Brain T; Fernando R; Robertson IK, 2013, 'Transcriptionally active human papillomavirus is strongly associated with Barrett's dysplasia and esophageal adenocarcinoma', American Journal of Gastroenterology,

Journal articles | 2013

Wang B; Rajendra S; Pavey D; Sharma P; Merrett N; Wu X; Snow ET; Kumbhari V; Ball MJ; Robertson IK, 2013, 'Viral load and integration status of high-risk human papillomaviruses in the barrett's metaplasia-dysplasia-adenocarcinoma sequence', American Journal of Gastroenterology, 108, pp. 1814 - 1816,

Journal articles | 2012

Rajendra S; Sharma P, 2012, 'Management of Barrett's oesophagus and intramucosal oesophageal cancer: A review of recent development', Therapeutic Advances in Gastroenterology, 5, pp. 285 - 299,

Journal articles | 2011

Rajendra S; Sharma P, 2011, 'Barrett's esophagus and cancer risk: a more realistic estimate', Seminars in Thoracic and Cardiovascular Surgery, 23, pp. 261 - 262,

Journal articles | 2011

Rajendra S, 2011, 'Barrett's oesophagus in Asians - are ethnic differences due to genes or the environment?', Journal of Internal Medicine, 270, pp. 421 - 427,

Journal articles | 2010

Rajendra S; Robertson IK, 2010, 'Similar immunogenetics of Barrett's oesophagus and cervical neoplasia: Is HPV the common denominator?', Journal of Clinical Pathology, 63, pp. 1 - 3,

Journal articles | 2009

Rajendra S; Kutty KM, 2009, 'Barrett's esophagus surveillance in asians', Journal of Clinical Gastroenterology, 43, pp. 1013 - 1014,

Journal articles | 2009

Rajendra S; Robertson IK, 2009, 'Barrett's oesophagus; acid and the human papilloma virus?', Journal of Clinical Virology, 44, pp. 176,

Journal articles | 2008

Rajendra S; Robertson IK, 2008, 'Ethnicity, GORD, Barrett's oesophagus and Helicobacter pylori infection', Gut, 57, pp. 1738

Journal articles | 2007

Rajendra S; Ackroyd R; Robertson IK; Ho JJ; Karim N; Kutty KM, 2007, 'Helicobacter pylori, ethnicity, and the gastroesophageal reflux disease spectrum: A study from the East', Helicobacter, 12, pp. 177 - 183,

Journal articles | 2006

Rajendra S; Ackroyd R; Karim N; Mohan C; Ho JJ; Kutty MK, 2006, 'Loss of human leucocyte antigen class I and gain of class II expression are early events in carcinogenesis: Clues from a study of Barrett's oesophagus', Journal of Clinical Pathology, 59, pp. 952 - 957,

Journal articles | 2006

Rajendra S; Ackroyd R; Murad S; Mohan C; Too CL; Azrena A, 2006, 'Barrett's oesophagus and HLA-B*0702/HLA-B*0706: Letters to the Editors [3]', Alimentary Pharmacology and Therapeutics, 23, pp. 1375 - 1376,

Journal articles | 2006

Rajendra S, 2006, 'Immunomodulatory effects of non-steroidal anti-inflammatory drugs in Barrett's oesophagus [4]', Lancet Oncology, 7, pp. 103 - 104,

Journal articles | 2005

Rajendra S; Ackroyd R; Mohan C, 2005, 'South Asian origin as a risk factor for GERD [1]', Alimentary Pharmacology and Therapeutics, 22, pp. 75 - 76,

Journal articles | 2005

Rajendra S; Ackroyd R; Murad S; Mohan C; Ho JJ; Goh KL; Azrena A; Too CL, 2005, 'Human leucocyte antigen determinants of susceptibility to Barrett's oesophagus in Asians - A preliminary study', Alimentary Pharmacology and Therapeutics, 21, pp. 1377 - 1383,

Journal articles | 2005

Rajendra S; Ho JJ; Arokiasamy J, 2005, 'Risk of colorectal adenomas in a multiethnic Asian patient population: Race does not matter', Journal of Gastroenterology and Hepatology (Australia), 20, pp. 51 - 55,

Journal articles | 2005

Rajendra S; Ho JJ, 2005, 'Colonic diverticular disease in a multiracial Asian patient population has an ethnic predilection', European Journal of Gastroenterology and Hepatology, 17, pp. 871 - 875,

Journal articles | 2005

Rajendra S; Ho JJ, 2005, 'GERD in British and south-east Asian dyspeptic patients [2]', Alimentary Pharmacology and Therapeutics, 22, pp. 580 - 581,

Journal articles | 2005

Rajendra S; Kutty K, 2005, 'Barrett's esophagus amongst Asians: Under-recognized and frequently missed? [3]', Journal of Gastroenterology and Hepatology (Australia), 20, pp. 164 - 167,

Journal articles | 2005

Rajendra S; Kutty K, 2005, 'Caecal tumour with hepatic metastases?', Gut, 54,

Journal articles | 2004

Rajendra S; Alahuddin S, 2004, 'Prevalence of irritable bowel syndrome in a multi-ethnic Asian population [2]', Alimentary Pharmacology and Therapeutics, 19, pp. 704 - 706,

Journal articles | 2004

Rajendra S; Alahuddin S, 2004, 'Racial differences in the prevalence of heartburn [1]', Alimentary Pharmacology and Therapeutics, 19, pp. 375 - 376,

Journal articles | 2004

Rajendra S; Baharain SRK; Karim N; Ho JJ; Kutty K, 2004, 'Ethnic disparity in the prevalence of partial villous atrophy and post-infective tropical malabsorption [2]', Journal of Gastroenterology and Hepatology (Australia), 19, pp. 472 - 474,

Journal articles | 2004

Rajendra S; Dharnal HK, 2004, 'Gastrointestinal: Tropical sprue', Journal of Gastroenterology and Hepatology (Australia), 19, pp. 1083,

Journal articles | 2004

Rajendra S; Dharnal HK, 2004, 'Images of interest. Gastrointestinal: tropical sprue.', Journal of gastroenterology and hepatology, 19, pp. 1083

Journal articles | 2004

Rajendra S; Kutty K; Karim N, 2004, 'Ethnic differences in the prevalence of endoscopic esophagitis and Barrett's esophagus: The long and short of it all', Digestive Diseases and Sciences, 49, pp. 237 - 242,

Journal articles | 2004

Rajendra S; Mulcahy H; Patchett S; Kumar P, 2004, 'The effect of H 2 antagonists on proliferation and apoptosis in human colorectal cancer cell lines', Digestive Diseases and Sciences, 49, pp. 1634 - 1640,

Journal articles | 2003

Rajendra S; Ho JJ, 2003, 'Post-infective tropical malabsorption and irritable bowel syndrome: Causality and mimicry? [3]', Alimentary Pharmacology and Therapeutics, 18, pp. 1174 - 1175,

Journal articles | 2003

Rajendra S; Kutty K; Karim N, 2003, 'Flat colonic adenomas in Malaysia: Fact or fancy?', Journal of Gastroenterology and Hepatology (Australia), 18, pp. 701 - 704,

Journal articles | 2003

Rajendra S; Zakaria S; Karim N; Zain Z, 2003, 'Ulcerative colitis and motor neurone disease: causal or coincidental?', Singapore Medical Journal, pp. 423 - 425

Journal articles | 1996

Rajendra S; Haider SI; Kumar PJ, 1996, 'New Developments in Gastroenterology', International Journal of Gastroenterology, pp. 20 - 22
Conference Papers | 2018

Wong M; Wang B; Yang A; Khor A; Xuan W; Rajendra S, 2018, 'Human papillomavirus exposure and sexual behavior are significant risk factors for Barrett's dysplasia/esophageal adenocarcinoma', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 25 - 26,

Conference Papers | 2015

Rajendra S; Wang B; Pavey D; Sharma P; Yang T; Lee CS; Gupta N; Ball MJ; Gill RS; Wu X, 2015, 'Persistence of human papillomavirus, overexpression of p53, and outcomes of patients after endoscopic ablation of Barrett's esophagus', in Journal of Gastroenterology and Hepatology, Wiley: 12 months, pp. 174 - 174

Conference Papers | 2014

Al-Haddad S; El-Zimaity H; Hafezi-Bakhtiari S; Rajendra S; Streutker CJ; Vajpeyi R; Wang B, 2014, 'Infection and esophageal cancer', in Annals of the New York Academy of Sciences, pp. 187 - 196,

Conference Papers | 2010

Chandran S; Middleton C; Mitchell B; Rajendra S, 2010, 'A look back at collagenous colitis: a 17-year retrospective study', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A22 - A22,

Conference Papers | 2010

Chandran S; Middleton C; Mitchell B; Rajendra S, 2010, 'A regional experience of oriental cholangiohepatitis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A21 - A21,

Conference Papers | 2010

Chandran S; Middleton C; Mitchell B; Rajendra S, 2010, 'A registrar's perspective on gastroenterology advanced training in regional Australia', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A21 - A22,

Conference Papers | 2009

Rajendra S; Ackroyd R; Mohan C; Kutty MK, 2009, 'HLA expression in Barrett's oesophagus', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A338 - A338,

Conference Papers | 2009

Rajendra S; Kutty MK, 2009, 'Barrett's oesophagus surveillance in asians', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A336 - A336,

Conference Papers | 2009

Rajendra S; Robertson IK; Snow ET; Ball MJ, 2009, 'Barrett's oesophagus and cervical neoplasia: hypothesis that hpv is the common denominator', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A336 - A336,

Conference Papers | 2009

Rajendra S; Snow ET; Lai HJ; Ball MJ; Robertson IK, 2009, 'Human papilloma virus and Barrett's oesophagus', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A338 - A338,

My research group focuses on the infectious causes of gastrointestinal cancer with a special emphasis on Barrett's oesophagus. It involves histopathology and molecular biology techniques. In the past five years, my group has actively developed new research concepts and implemented them in the laboratory investigation pertaining to human papillomavirus (HPV) and Barrett’s dysplasia (BD) and oesophageal adenocarcinoma (OAC). My group demonstrated world first study on strong association of transcriptionally active high-risk HPV (hr-HPV) with BD and OAC and increasing hr-HPV viral load is linked with greater disease severity along the Barrett’s metaplasia-dysplasia-adenocarcinoma sequence. The findings have the potential to lead to vaccination against a subset of oesophageal cancer.

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Professor Shan Rajendra

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