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Dr Tianruo Guo

Dr Tianruo Guo

Lecturer
Engineering
Grad Sch: Biomedical Eng

Dr Tianruo Guo is听currently a Lecturer of Neuromodulation and an Early Career Academic Fellow with the Graduate School of Biomedical Engineering, UNSW. Guo uses computational analyses to guide the biological experimental design. Guo鈥檚 research interests include large-scale optimization for developing accurate ionic models of cardiac myocytes and neural cells, and biomedical signal processing. He is currently working in GSBmE to develop advanced electrical stimulation strategies for a visual prosthesis.

Guo has extensive experience in computational modelling since completing his Master degree in cardiac modelling and his PhD in simulating electrical activity in the mammalian retina. Over the past several years he has expanded his research skills greatly from that of theoretical modelling to also include retinal neuroscience. Guo has recently performed patch-clamp experiments in retinal tissue to validate his sophisticated computational models. With this deep insight he has proposed a new stimulation scheme using high frequency waveforms that will allow different classes of retinal ganglion cells (the ON and OFF pathways) to be selectively excited. This has enormous potential in the design of visual prostheses as it will allow more realistic recreation of the visual scene 鈥 previously not possible with current state-of-the-art retinal neuroprostheses.

TEACHING

Engineering in Medicine and Biology - BIOM1010 (2017)

Implantable Bionics / Bionic and Neuromodulation- BIOM9660 (2017-now)

Biomedical Instrumentation - BIOM9640 (2019-now)

GRANTS, AWARDS AND SCHOLARSHIP

  1. UNSW-CAS Collaborative Research Bridging Grant (2019-2020)

  2. UNSW-CAS Collaborative Research Mobility Grant (2019)

  3. Retina Australia Research Fund (2018)

  4. Australia-Germany Joint Research Co-operation Scheme (DAAD, 2018-2019)

  5. SJTU-UNSW Collaborative Research Fund (2018-2020)

  6. Ian Potter Foundation Travel Fund (2018)

  7. UNSW Research Infrastructure Scheme (RIS, 2019)

  8. Australian Biomedical Engineering Conference (ABEC), Best Poster Presentation Award (2018).听

  9. Chinese Academy of Sciences Travel Grant (2015)

  10. PhD Scholarship in Excitable Tissue Computational Modelling (2011-2014)

  11. UNSW Postdoctoral Writing Fellowship Grant (2014)

  12. IEEE Engineering in Medicine and Biology Society, Student Paper Competition,Asia Pacific Finalist Award (2014)听

  13. IEEE Engineering in Medicine and Biology Society, Student Paper Competition, Asia Pacific Finalist Award听(2013)

  14. IEEE Engineering in Medicine and Biology Society, Student Paper Competition, Second Place (2013)

  15. Australian Biomedical Engineering Conference (ABEC), Best Presentation Award (2013).听

  16. Australian Workshop on Computational Neuroscience,听NeuroEng Student Prize (2013).听

  17. Australian Biomedical Engineering Conference (ABEC) Travel Sponsorship (2013)

  18. Postgraduate Research Student Support Conference Travel Grant (2014)

  19. China Scholarship Council (CSC) National Scholarship for Outstanding Self-Funded Student Finalist (NSW division, 2014)听

  20. UNSW Dean鈥檚 Award for Excellence in Postgraduate Research Finalist (2013)

PUBLICATIONS

Refereed journal articles

  1. Siwei Bai, Donel Martin, Tianruo Guo, Socrates Dokos, Colleen Loo (2019), Computational Comparison of Conventional and Novel Electroconvulsive Therapy Electrode Placements for the Treatment of Depression, European Psychiatry. Vol. 60, pp 71-78.
  2. Tianruo Guo*, David Tsai*, Chih Yu Yang, Perry Twyford, Shelley I. Fried, John W. Morley, Gregg J. Suaning, Socrates Dokos and Nigel H. Lovell (2019), Mediating retinal ganglion cell spike rates using high-frequency electrical stimulation, Frontiers in Neuroscience. doi: 10.3389/fnins.2019.00413
  3. Tianruo Guo*, Yang, C*, Tsai, D, Madhuvanthi, M, Suaning, GJ, Morley, JW, Dokos, S, Lovell, NH (2018) Closed-loop efficient searching of optimal electrical stimulation parameters for preferential excitation of retinal ganglion cells, Frontiers in Neuroscience. doi: 10.3389/fnins.2018.00168
  4. Chih Yu Yang,听David Tsai,听Tianruo Guo,听Socrates Dokos,听Gregg J Suaning,听John W Morley听and听Nigel H Lovell (2018), 鈥淒ifferential Electrical Responses in Retinal Ganglion Cell Subtypes: Effects of Synaptic Blockade and Stimulating Electrode Location鈥, Journal of Neural Engineering, doi:
  5. Barriga-Rivera, A., Tianruo Guo., Yang, C., Al Abed, A., Dokos, S., Lovell, N. H., Morley, J. W., Suaning, G. J. (2017), 鈥淗igh-amplitude electrical stimulation can reduce elicited neuronal activity in visual prosthesis,鈥 Scientific Reports. 2017;7:42682.
  6. Tianruo Guo, Tsai, D., Morley, J. W., Suaning, G. J., Kameneva, T., Lovell, N. H., Dokos, S. (2015), 鈥淓lectrical Activity of ON and OFF Retinal Ganglion Cells: A Modelling Study,鈥 2015, Journal of Neural Engineering. 13 025005.
  7. Tianruo Guo, David Tsai, John. W. Morley, Gregg. J. Suaning, Nigel. H. Lovell, Socrates. Dokos (2014), 鈥淯nderstanding the retina: a review of computational models of the retina from the single-cell to network level,鈥 Critical Reviews in Biomedical Engineering. Vol. 42(5), pp 491-436, doi: 10.1615/CritRevBiomedEng.2014011732
  8. Tianruo听Guo,听Amr Al Abed, Nigel H. Lovell, and Socrates Dokos (2013), 鈥淥ptimisation of a Generic Ionic Model of Cardiac听Myocyte Electrical Activity,鈥 Computational and Mathematical Methods in Medicine, vol. 2013, Article ID 706195, 20 pages, 2013. doi:10.1155/2013/706195
  9. Amr听Al Abed,听Tianruo Guo, Nigel H. Lovell, and Socrates Dokos, 鈥淥ptimisation of Ionic Models to Fit Tissue Action Potentials: Application to听3D听Atrial Modelling,鈥 Computational and Mathematical Methods in Medicine, vol. 2013, Article ID 951234, 16 pages, 2013. doi:10.1155/2013/95123
  10. Hong-Bo Xie,听Tianruo Guo,听Siwei听Bai and Socrates Dokos, 鈥淗ybrid soft computing systems for听electromyographic signals analysis: a review,鈥澨鼴iomedical Engineering Online, vol. 13(8), 2014. doi:10.1186/1475-925X-13-8
  11. Hong-Bo Xie, Tianruo Guo, Bellie Sivakumar, Alan Wee-Chung Liew and Socrates Dokos, 鈥淪ymplectic geometry spectrum analysis of nonlinear time series,鈥 Proceedings of the Royal Society A. vol. 470(2170), 2014. doi:10.1098/rspa.2014.0409
  12. Hong-bo Xie, Ping Zhou, Tianruo Guo, B. Sivakumar, Xu. Zhang, and S. Dokos, 鈥淢ulti-scale two-directional two-dimensional principal component analysis and its application to high-dimensional biomedical signal classification,鈥 IEEE Transactions on Biomedical Engineering, vol. 63 (7), doi:

Refereed conference papers only when the paper was published in full in the proceedings

  1. N Wang, X Song, T Li, T Guo, L Li, A preliminary study on virtual electrode for subretinal prostheses by computational model, Engineering in Medicine and Biology Society (EMBC), 2019 Annual International Conference of the IEEE
  2. T. Guo, D. Tsai, Madhuvanthi, M, L. Li, G. J. Suaning, J. W. Morley, S. Dokos, N. H. Lovell, Computational models and tools for developing sophisticated stimulation strategies for retinal neuroprostheses, Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE.
  3. T. Guo, A. Barriga-Rivera, G J. Suaning, D Tsai, J. W. Morley, S Dokos, N H. Lovell, Mimicking Natural Neural Encoding through Retinal Electrostimulation, 2017 Annual International Conference of the IEEE on Neural Engineering.
  4. H. Xie, T. Guo, Fuzzy Entropy Spectrum Analysis for Biomedical Signals De-Noising, 2018 IEEE International Conference on Biomedical and Health Informatics
  5. A. Barriga-Rivera, T. Guo, J. W. Morley, S Dokos, N H. Lovell, G J. Suaning, Retinal Electrostimulation in Rats: Activation Thresholds from Superior Colliculus and Visual Cortex Recordings, Engineering in Medicine and Biology Society (EMBC), 2017 Annual International Conference of the IEEE.
  6. A. Alqahtani, A. Abed, T Guo, N. H. Lovell and S. Dokos, A Continuum Model of Electrical Stimulation of Multi-Compartmental Retinal Ganglion Cells锛 Engineering in Medicine and Biology Society (EMBC), 2017 Annual International Conference of the IEEE.
  7. C. Y. Yang, D. Tsai, T. Guo, G. J. Suaning, S. Dokos, J. W. Morley, N. H. Lovell, High Frequency Electrical Stimulation: the Effect of Spatial Location on Retinal Ganglion Cell Responses In vitro, Engineering in Medicine and Biology Society (EMBC), 2016 Annual International Conference of the IEEE.
  8. T. Guo, N H. Lovell, D Tsai, G J. Suaning, S Dokos, Optimizing retinal ganglion cell responses to high-frequency electrical stimulation strategies for preferential neuronal excitation, Engineering in Medicine and Biology Society (EMBC), 2015 Annual International Conference of the IEEE on Neural Engineering (Invited paper).
  9. Siwei Bai, T. Guo, D Tsai, G J. Suaning, N H. Lovell, S Dokos, Influence of Dendritic Morphology on the Dynamic Properties of Retinal Ganglion Cells: A Computational Study, Engineering in Medicine and Biology Society (EMBC), 2015 Annual International Conference of the IEEE on Neural Engineering.
  10. T. Guo, N. H. Lovell, D. Tsai, P. Twyford, S. Fried, J. W. Morley, G. J. Suaning and S. Dokos, Selective Activation of ON and OFF Retinal Ganglion Cells to High-frequency Electrical Stimulation: A Computational Modeling Study, Engineering in Medicine and Biology Society (EMBC), 2014 Annual International Conference of the IEEE (EMBS Student Paper Competition, Asia Pacific Finalist)
  11. T. Guo, D. Tsai, J. W. Morley, G. J. Suaning, N. H. Lovell, S. Dokos, The Unique Characteristics of ON and OFF Retinal Ganglion Cells: A Modeling Study, Engineering in Medicine and Biology Society (EMBC), 2014 Annual International Conference of the IEEE
  12. T Guo, D Tsai, J. W. Morley, G J. Suaning, N H. Lovell, S Dokos, Influence of Cell Morphology in a Computational Model of ON and OFF Retinal Ganglion Cells, Engineering in Medicine and Biology Society (EMBC), 2013 Annual International Conference of the IEEE
  13. T. Guo, D Tsai, S. Sovilj, J. W. Morley, G J. Suaning, N H. Lovell, S Dokos, Influence of Active Dendrites on Firing Patterns in a Retinal Ganglion Cell Model, Engineering in Medicine and Biology Society (EMBC), 2013 Annual International Conference of the IEEE
  14. T. Guo, D Tsai, J. W. Morley, G J. Suaning, N H. Lovell, S Dokos, Cell-specific Modeling of Retinal Ganglion Cell Electrical Activity, Engineering in Medicine and Biology Society (EMBC), 2013 Annual International Conference of the IEEE (EMBS Student Paper Competition, Asia Pacific Finalist)
  15. T. Guo, D Tsai, G J. Suaning, N H. Lovell, S Dokos, Modelling Normal and Rebound Excitation in Mammalian Retinal Ganglion Cells, Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE.
  16. A Bradd, A Al Abed, T. Guo, N. H. Lovell and S. Dokos, Study of Sinoatrial Excitation using an Optimized Generic Model and Realistic Geometry. Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
  17. T. Guo, A. Al Abed, N. H. Lovell and S. Dokos, Parameter Fitting using Multiple Datasets in Cardiac Action Potential Modeling.
  18. A. Al Abed, T. Guo, N. H. Lovell and S. Dokos, Tissue-Based Optimization of a Sino-Atrial Node Disc Model. 听
  19. T. Guo, A. Al Abed, N. H. Lovell and S. Dokos, A Generic Ionic Model of Cardiac Action Potential.
  20. A. Al Abed, T. Guo, N. H. Lovell and S. Dokos, An anatomically realistic 3D model of atrial propagation based on experimentally recorded action potentials.

Patent

  1. A. Barriga-Rivera, T. Guo, G. Suaning, J. W. Morley, N. H. Lovell. A method and apparatus for facilitating artificial vision. PCT/AU2017/050645

Conference Abstract

  1. Socrates Dokos, T. Guo, Liming Li, Nigel Lovell, Selective Activation of Retinal Ganglion Cells, invited session, Computational Systems & Synthetic Biology; Multiscale Modeling, Engineering in Medicine and Biology Society (EMBC), 2019 Annual International Conference of the IEEE.
  2. Madhuvanthi Muralidharan, T. Guo, John W. Morley, Socrates Dokos, Nigel H. Lovell, Effective Stimulation Approaches to Mimic Physiological Neural Encoding of Retinal Ganglion Cells, Australian Biomedical Engineering Conference (ABEC), 2018. (Best Poster Presentation Award)
  3. Gregg J. Suaning, John W. Morley, Nigel H. Lovell, T Guo, Socrates Dokos, Alejandro Barriga-Rivera, Retinal neuromodulation and the neural code - lost in translation? Artificial vision: latest progress and challenges ahead, Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE.
  4. S. Dokos, T. Guo, N. H. Lovell, Computational Modelling of Retinal Electrical Stimulation, Simulation of Neurological Disorders and their Treatment with Neuromodulation, Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE.
  5. Al Abed,听T. Guo, N. H. Lovell, and S. Dokos, A Model of atrial propagation based on in vitro action potential records. The 30th Annual Meeting of the Australian Neuroscience Society and the 50th Anniversary Meeting of the Australian Physiological Society, Sydney, 2010
  6. T Guo, D Tsai, G J Suaning, N H Lovell S Dokos, A modified retinal ganglion cell model, the 3rd International Conference on Neuroprosthetic Devices (ICND), Sydney, 2011.听
  7. T Guo, D Tsai, G J Suaning, N H Lovell S Dokos, Influence of cell morphology in computational models of ON and OFF retinal ganglion cells, AuPS/PSNZ/ASB Joint Meeting, Sydney, 2012.
  8. T Guo, D Tsai, G J Suaning, N H Lovell S Dokos, Influence of dendritic structure on retinal ganglion cell firing pattern: a modeling study, NeuroEng 2013: 6th Australian Workshop on Computational Neuroscience, Melbourne, Australia (NeuroEng Student Prize).
  9. T Guo, D Tsai, G J Suaning, N H Lovell S Dokos, A generic modelling approach for reconstructing retinal ganglion cell electrical activity, Australian Biomedical Engineering Conference (ABEC), 2013. (Best Presentation Award)
  10. Barriga-Rivera, T. Guo, N. H. Lovell, J. W. Morley, and G. J. Suaning High-density simultaneous recordings from visual cortex and superior colliculus in a rat: a pilot study in retinal prosthesis2017 International Conference on Cancer Nursing (ICCN), 2017.
  11. J W Morley, C-Y Yang, D Tsai, T Guo, G Suaning, S Dokos, N H Lovell, High Frequency Electrical Stimulation: the Effect of Spatial Location on Retinal Ganglion Cell Responses In Vitro, Neuroscience 2016, San Diego CA, USA, 2016.

Invited talk

  1. 鈥淩eplicating a more physiological retinal neural code using high-rate electrical stimulation鈥, Eye and The Chip world research congress, November 2019, Detroit, US.
  2. 鈥淥ptimizing the performance of retinal neuroprostheses with high-frequency electrical stimulation, Artificial vision: latest progress and challenges ahead鈥, Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE. August, 2018, Honolulu.
  3. 鈥淣ext generation of neural interface鈥, UNSW China roadshow, Chinese Academy of Sciences, Feb, 2018, Beijing.
  4. 鈥淪elective activation of retinal neurons using artificial electrical stimulation鈥, Shanghai Institute of Neuroscience, Chinese Academy of Sciences, August, 2015, Shanghai.
  5. 鈥淣eural interface: a bridge between engineering and biology鈥, UNSW China roadshow, Shanghai Jiao Tong University (SHJT), October, 2015, Shanghai.
  6. 鈥淏ionic eye, seeing, and not seeing the light鈥, Brain Awareness Session, Donald Wihelm Museum of Human Disease, March, 2018, Sydney.
  7. 鈥淚mplantable bionics鈥, High School Science Teacher鈥檚 Day, Donald Wihelm Museum of Human Disease, April, 2017, Sydney.
  8. 鈥淚nterface between biology and engineering鈥, Beijing University of Chemical technology (BUCT). October, 2016, Beijing.
  9. 鈥淥ptimizing the activation of retinal neurons using artificial electrical stimulation鈥, Jingmeng Hi-Tech, October, 2014, Beijing.
Phone
043/019-8542
Location
Room 1005 Level 1 Bioscience South (E26) The Graduate School of Biomedical Engineering UNSW SYDNEY NSW 2052 AUSTRALIA
  • Book Chapters | 2023
    Guo T; Shivdasani MN; Tsai D; Ayton LN; Rathbun DL; Lovell NH, 2023, 'Visual Prostheses: Neuroengineering Handbook', in Handbook of Neuroengineering, Springer Nature Singapore, pp. 1023 - 1068,
    Book Chapters | 2022
    Dokos S; Guo T, 2022, 'Computational Models of Neural Retina', in Encyclopedia of Computational Neuroscience, Springer New York, pp. 912 - 930,
    Book Chapters | 2021
    Guo T; Shivdasani MN; Tsai D; Ayton LN; Rathbun DL; Lovell NH, 2021, 'Visual Prostheses: Neuroengineering Handbook', in Handbook of Neuroengineering, Springer Singapore, pp. 1 - 46,
    Book Chapters | 2020
    Dokos S; Guo T, 2020, 'Computational Models of Neural Retina', in Jaeger D; Jung R (ed.), Encyclopedia of Computational Neuroscience,
    Book Chapters | 2020
    Guo T; Tsai D; Bai S; Shivdasani M; Muralidharan M; Li L; Dokos S; Lovell N, 2020, 'Insights from Computational Modelling: Selective Stimulation of Retinal Ganglion Cells', in Brain and Human Body Modeling 2020, Springer Nature,
    Book Chapters | 2016
    Xie HB; Guo T, 2016, 'Two-directional two-dimensional principal component analysis based on wavelet decomposition for high-dimensional biomedical signals classification', in Computational Tools and Techniques for Biomedical Signal Processing, pp. 100 - 122,
  • Journal articles | 2024
    Chia S; Guo T; Goldys EM; Payne SC; Duan W; Lovell NH; Shivdasani MN; Deng F, 2024, 'A CRISPR mediated point-of-care assay for the detection of mucosal calprotectin in an animal model of ulcerative colitis', Bioengineering and Translational Medicine,
    Journal articles | 2024
    Liang J; Li H; Chai X; Gao Q; Zhou M; Guo T; Chen Y; Di L, 2024, 'An audiovisual cognitive optimization strategy guided by salient object ranking for intelligent visual prothesis systems', Journal of Neural Engineering, 21, pp. 066021 - 066021,
    Journal articles | 2024
    Muralidharan M; Guo T; Tsai D; Lee JI; Fried S; Dokos S; Morley JW; Lovell NH; Shivdasani MN, 2024, 'Neural activity of retinal ganglion cells under continuous, dynamically-modulated high frequency electrical stimulation', Journal of Neural Engineering, 21, pp. 015001,
    Journal articles | 2024
    Song X; Guo T; Ma S; Zhou F; Tian J; Liu Z; Liu J; Li H; Chen Y; Chai X; Li L, 2024, 'Spatially Selective Retinal Ganglion Cell Activation Using Low Invasive Extraocular Temporal Interference Stimulation', International Journal of Neural Systems, 35, pp. 2450066,
    Journal articles | 2024
    Wang X; Zhang Y; Guo T; Wu S; Zhong J; Cheng C; Sui X, 2024, 'Selective intrafascicular stimulation of myelinated and unmyelinated nerve fibers through a longitudinal electrode: A computational study', Computers in Biology and Medicine, 176, pp. 108556 - 108556,
    Journal articles | 2024
    Xu Z; Chen Z; Yang S; Chen S; Guo T; Chen H, 2024, 'Passive Focusing of Single Cells Using Microwell Arrays for High-Accuracy Image-Activated Sorting', Analytical Chemistry, 96, pp. 347 - 354,
    Journal articles | 2024
    Xue R; Deng F; Guo T; Epps A; Lovell NH; Shivdasani MN, 2024, 'Needle-Shaped Biosensors for Precision Diagnoses: From Benchtop Development to In Vitro and In Vivo Applications', Biosensors, 14,
    Journal articles | 2024
    Yu Z; Chen Y; Li J; Chen C; Lu H; Chen S; Zhang T; Guo T; Zhu Y; Jin J; Yan S; Chen H, 2024, 'A tempo-spatial controllable microfluidic shear-stress generator for in-vitro mimicking of the thrombus', Journal of Nanobiotechnology, 22,
    Journal articles | 2023
    Guo T; Chang YC; Li L; Dokos S; Li L, 2023, 'Editorial: Advances in bioelectronics and stimulation strategies for next generation neuroprosthetics', Frontiers in Neuroscience, 16,
    Journal articles | 2023
    Ly K; Lovell NH; Muralidharan M; Italiano ML; Tsai D; Shivdasani MN; Guo T; Dokos S, 2023, 'The direct influence of retinal degeneration on electrical stimulation efficacy: Significant implications for retinal prostheses', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,
    Journal articles | 2023
    Qin P; Lin Q; Xie Y; Chang YC; Zanos S; Wang H; Payne S; Shivdasani MN; Tsai D; Lovell NH; Dokos S; Guo T, 2023, 'Modulating functionally-distinct vagus nerve fibers using microelectrodes and kilohertz frequency electrical stimulation', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,
    Journal articles | 2023
    Xie Y; Qin P; Guo T; Al Abed A; Lovell NH; Tsai D, 2023, 'Modulating individual axons and axonal populations in the peripheral nerve using transverse intrafascicular multichannel electrodes', Journal of Neural Engineering, 20,
    Journal articles | 2023
    Yu S; Yue W; Guo T; Liu Y; Zhang Y; Khademi S; Zhou T; Xu Z; Song B; Wu T; Liu F; Tai Y; Yu X; Wang H, 2023, 'The effect of the subthreshold oscillation induced by the neurons' resonance upon the electrical stimulation-dependent instability', Frontiers in Neuroscience, 17,
    Journal articles | 2023
    Zha M; Muralidharan M; Ly K; Guo T; Von Wegner F; Shabani H; Hosseinzadeh Z; Lovell NH; Rathbun DL; Shivdasani MN, 2023, 'Probing the Contribution of Vertical Processing Layers of the Retina to White-Noise Electrical Stimulation Responses', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,
    Journal articles | 2022
    Chang YC; Ahmed U; Jayaprakash N; Mughrabi I; Lin Q; Wu YC; Gerber M; Abbas A; Daytz A; Gabalski AH; Ashville J; Dokos S; Rieth L; Datta-Chaudhuri T; Tracey KJ; Guo T; Al-Abed Y; Zanos S, 2022, 'kHz-frequency electrical stimulation selectively activates small, unmyelinated vagus afferents', Brain Stimulation, 15, pp. 1389 - 1404,
    Journal articles | 2022
    Chen C; Li P; Guo T; Chen S; Xu D; Chen H, 2022, 'Generation of Dynamic Concentration Profile Using A Microfluidic Device Integrating Pneumatic Microvalves', Biosensors, 12,
    Journal articles | 2022
    Chen C; Meng H; Guo T; Deshpande S; Chen H, 2022, 'Development of Paper Microfluidics with 3D-Printed PDMS Barriers for Flow Control', ACS Applied Materials and Interfaces, 14, pp. 40286 - 40296,
    Journal articles | 2022
    Italiano ML; Guo T; Lovell NH; Tsai D, 2022, 'Improving the spatial resolution of artificial vision using midget retinal ganglion cell populations modeled at the human fovea', Journal of Neural Engineering, 19,
    Journal articles | 2022
    Liu Y; Yue W; Yu S; Zhou T; Zhang Y; Zhu R; Song B; Guo T; Liu F; Huang Y; Wu T; Wang H, 2022, 'A physical perspective to understand myelin II: The physical origin of myelin development', Frontiers in Neuroscience, 16,
    Journal articles | 2022
    Liu Y; Yue W; Yu S; Zhou T; Zhang Y; Zhu R; Song B; Guo T; Liu F; Huang Y; Wu T; Wang H, 2022, 'A physical perspective to understand myelin. I. A physical answer to Peter鈥檚 quadrant mystery', Frontiers in Neuroscience, 16,
    Journal articles | 2022
    Lu Z; Zhou M; Guo T; Liang J; Wu W; Gao Q; Li L; Li H; Chai X, 2022, 'An in-silico analysis of retinal electric field distribution induced by different electrode design of trans-corneal electrical stimulation', Journal of Neural Engineering, 19,
    Journal articles | 2022
    Ly K; Guo T; Tsai D; Muralidharan M; Shivdasani MN; Lovell NH; Dokos S, 2022, 'Simulating the impact of photoreceptor loss and inner retinal network changes on electrical activity of the retina', Journal of Neural Engineering, 19,
    Journal articles | 2022
    Song X; Qiu S; Shivdasani MN; Zhou F; Liu Z; Ma S; Chai X; Chen Y; Cai X; Guo T; Li L, 2022, 'An in-silico analysis of electrically evoked responses of midget and parasol retinal ganglion cells in different retinal regions', Journal of Neural Engineering, 19,
    Journal articles | 2022
    Guo T; Liu Y; Shao G; Engel BA; Sharma A; Marshall LA; Flanagan DC; Cibin R; Wallace CW; Zhao K; Ren D; Vera Mercado J; Aboelnour MA, 2022, 'Improving probabilistic monthly water quantity and quality predictions using a simplified residual-based modeling approach', Environmental Modelling and Software, vol. 156,
    Journal articles | 2021
    Chang Y-C; Ahmed U; Jayaprakash N; Mughrabi I; Lin Q; Wu Y-C; Gerber M; Abbas A; Daytz A; Gabalski AH; Ashville J; Dokos S; Rieth L; Datta-Chaudhury T; Tracey K; Guo T; Al-Abed Y; Zanos S, 2021, 'Intermittent KHz-frequency electrical stimulation selectively engages small unmyelinated vagal afferents', ,
    Journal articles | 2020
    Barriga-Rivera A; Guo T; Hayashida Y; Suaning GJ, 2020, 'Editorial: A Conversation With the Brain: Can We Speak Its Language?', Frontiers in Neuroscience, 14,
    Journal articles | 2020
    Ge Y; Ye S; Zhu K; Guo T; Su D; Zhang D; Chen Y; Chai X; Sui X, 2020, 'Mediating different-diameter A尾 nerve fibers using a biomimetic 3D TENS computational model', Journal of Neuroscience Methods, 346,
    Journal articles | 2020
    Muralidharan M; Guo T; Shivdasani MN; Tsai D; Fried S; Li L; Dokos S; Morley JW; Lovell NH, 2020, 'Neural activity of functionally different retinal ganglion cells can be robustly modulated by high-rate electrical pulse trains', Journal of Neural Engineering, 17,
    Journal articles | 2020
    Rathbun DL; Shivdasani MN; Guo T; Fried S; Lovell NH; Hessburg P, 2020, 'The eye and the chip 2019 - Conference Report', Journal of Neural Engineering, 17, pp. 010401,
    Journal articles | 2020
    Song X; Guo T; Shivdasani MN; Dokos S; Lovell NH; Li X; Qiu S; Li T; Zheng S; Li L, 2020, 'Creation of virtual channels in the retina using synchronous and asynchronous stimulation - A modelling study', Journal of Neural Engineering, 17,
    Journal articles | 2019
    Bai S; Martin D; Guo T; Dokos S; Loo C, 2019, 'Computational comparison of conventional and novel electroconvulsive therapy electrode placements for the treatment of depression', European Psychiatry, 60, pp. 71 - 78,
    Journal articles | 2019
    Guo T; Tsai D; Yang CY; Al Abed A; Twyford P; Fried SI; Morley JW; Suaning GJ; Dokos S; Lovell NH, 2019, 'Mediating retinal ganglion cell spike rates using high-frequency electrical stimulation', Frontiers in Neuroscience, 13, pp. 413,
    Journal articles | 2019
    Office FP; Al Abed A; Guo T; Tsai D, 2019, 'Erratum: Mediating Retinal Ganglion Cell Spike Rates Using High-Frequency Electrical Stimulation', Frontiers in Neuroscience, 13, pp. 910,
    Journal articles | 2018
    Guo T; Yang CY; Tsai D; Muralidharan M; Suaning G; Morley J; Dokos S; Lovell N, 2018, 'Closed-Loop Efficient Searching of Optimal Electrical Stimulation Parameters for Preferential Excitation of Retinal Ganglion Cells', Frontiers in Neuroscience, 12, pp. 168,
    Journal articles | 2018
    Yang CY; Tsai D; Guo T; Dokos S; Suaning G; Morley JM; Lovell N; Morley J, 2018, 'Differential Electrical Responses in Retinal Ganglion Cell Subtypes: Effects of Synaptic Blockade and Stimulating Electrode Location', Journal of Neural Engineering, 15, pp. 046020,
    Journal articles | 2017
    Barriga-Rivera A; Guo T; Yang CY; Abed AA; Dokos S; Lovell NH; Morley JW; Suaning GJ; Al Abed A, 2017, 'High-amplitude electrical stimulation can reduce elicited neuronal activity in visual prosthesis', Scientific Reports, 7, pp. 42682,
    Journal articles | 2016
    Guo T; Tsai D; Morley JW; Suaning GJ; Kameneva T; Lovell NH; Dokos S, 2016, 'Electrical activity of on and off retinal ganglion cells: A modelling study', Journal of Neural Engineering, 13,
    Journal articles | 2016
    Xie HB; Zhou P; Guo T; Sivakumar B; Zhang X; Dokos S, 2016, 'Multiscale Two-Directional Two-Dimensional Principal Component Analysis and Its Application to High-Dimensional Biomedical Signal Classification', IEEE Transactions on Biomedical Engineering, 63, pp. 1416 - 1425,
    Journal articles | 2014
    Guo T; Tsai D; Bai S; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2014, 'Understanding the retina: A review of computational models of the retina from the single cell to the network level', Critical Reviews in Biomedical Engineering, 42, pp. 419 - 436,
    Journal articles | 2014
    Xie HB; Guo T; Bai S; Dokos S, 2014, 'Hybrid soft computing systems for electromyographic signals analysis: A review', BioMedical Engineering Online, 13, pp. 8,
    Journal articles | 2014
    Xie HB; Guo T; Sivakumar B; Liew AWC; Dokos S, 2014, 'Symplectic geometry spectrum analysis of nonlinear time series', Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 470,
    Journal articles | 2013
    Al Abed A; Guo T; Lovell NH; Dokos S, 2013, 'Optimisation of ionic models to fit tissue action potentials: Application to 3D atrial modelling', Computational and Mathematical Methods in Medicine, 2013, pp. 951234,
    Journal articles | 2013
    Guo T; Al Abed A; Lovell NH; Dokos S, 2013, 'Erratum: Optimisation of a generic ionic model of cardiac myocyte electrical activity (Computational and Mathematical Methods in Medicine)', Computational and Mathematical Methods in Medicine, 2013,
    Journal articles | 2013
    Guo T; Al abed A; Lovell NH; Dokos S, 2013, 'Optimisation of a generic ionic model of cardiac myocyte electrical activity', Computational and Mathematical Methods in Medicine, 2013, pp. Article number706195,
  • Preprints | 2024
    Chia S; Guo T; Goldys E; Payne S; Lovell N; Shivdasani M; Deng F, 2024, A CRISPR mediated point-of-care assay for the detection of mucosal calprotectin in an animal model of ulcerative colitis,
    Preprints | 2024
    Cortesi M; Li J; Liu D; Guo T; Dokos S; Warton K; Ford C, 2024, A novel approach for the quantification of single-cell adhesion dynamics from microscopy images,
    Conference Papers | 2023
    Cai Y; Chen S; Xu D; Guo T; Jin J; Chen H, 2023, 'Automatic elasticity measurement of single cells using a microfluidic system with real-time image processing', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), United States, pp. 1 - 4, presented at 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), United States, 24 July 2023 - 27 July 2023,
    Conference Papers | 2023
    Liu J; Song X; Zhou F; Ma S; Liu Z; Li J; Chai X; Li L; Guo T, 2023, 'Suprachoroidal Retinal Stimulation Leveraging Temporal Interference Technology: A Modelling Study', in Proceedings - 2023 16th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics, CISP-BMEI 2023,
    Conference Papers | 2023
    Liu J; Song X; Zhou F; Ma S; Liu Z; Li X; Chai X; Li L; Guo T, 2023, 'Suprachoroidal Retinal Stimulation Leveraging Temporal Interference Technology', China, presented at 2023 16th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI), China, 28 October 2023,
    Conference Papers | 2023
    Ly K; Lovell NH; Muralidharan M; Italiano ML; Tsai D; Shivdasani MN; Guo T; Dokos S, 2023, 'The direct influence of retinal degeneration on electrical stimulation efficacy: Significant implications for retinal prostheses', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), United States, pp. 1 - 4, presented at 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), United States, 24 July 2023 - 27 July 2023,
    Conference Papers | 2023
    Ma S; Song X; Guo T; Zhou F; Liu Z; Chai X; Li L, 2023, 'Improving Spatial Resolution and Selectivity of Transcorneal Electrical Stimulation by Temporal Interference Technology', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), United States, pp. 1 - 4, presented at 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), United States, 24 July 2023 - 27 July 2023,
    Conference Papers | 2023
    Qin P; Lin Q; Xie Y; Chang YC; Zanos S; Wang H; Payne S; Shivdasani MN; Tsai D; Lovell NH; Dokos S; Guo T, 2023, 'Modulating functionally-distinct vagus nerve fibers using microelectrodes and kilohertz frequency electrical stimulation', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), United States, pp. 1 - 4, presented at 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), United States, 24 July 2023 - 27 July 2023,
    Preprints | 2023
    Yu S; Yue W; Guo T; Liu Y; Zhang Y; Khademi S; Zhou T; Xu Z; Song B; Wu T; Liu F; Tai Y; Yu X; Wang H, 2023, The Effect of Electrical Resonance in Neurons upon the Instability of Electrical Nerve Stimulations,
    Conference Papers | 2023
    Yue W; Yu S; Guo T; Wang H, 2023, 'A Self-powered Neural Stimulator Based on Programmable Triboelectric Nanogenerators', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), United States, pp. 1 - 4, presented at 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), United States, 24 July 2023 - 27 July 2023,
    Conference Papers | 2023
    Zha M; Muralidharan M; Ly K; Guo T; Von Wegner F; Shabani H; Hosseinzadeh Z; Lovell NH; Rathbun DL; Shivdasani MN, 2023, 'Probing the Contribution of Vertical Processing Layers of the Retina to White-Noise Electrical Stimulation Responses', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), United States, pp. 1 - 4, presented at 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), United States, 24 July 2023 - 27 July 2023,
    Conference Papers | 2021
    Italiano M; Guo T; Lovell N; Tsai D, 2021, 'Exploring the limits of artificial vision using a model of foveal retinal ganglion cells', in Proceedings of the Neural Interfaces and Artificial Senses, Fundaci贸 Scito, presented at Neural Interfaces and Artificial Senses, 22 September 2021 - 23 September 2021,
    Preprints | 2021
    Liu Y; Zhang Y; Yue W; Zhu R; Guo T; Liu F; Huang Y; Wu T; Wang H, 2021, A physical perspective to understand myelin. I. Peters quadrant mystery, ,
    Preprints | 2021
    Liu Y; Zhang Y; Yue W; Zhu R; Guo T; Liu F; Huang Y; Wu T; Wang H, 2021, A physical perspective to understand myelin. II. The physical origin of myelin development, ,
    Conference Papers | 2021
    Song X; Wu D; Qiu S; Liu Z; Zhou F; Ma S; Li L; Guo T, 2021, 'Insights from computational modelling: Characterising Midget and Parasol Retinal Ganglion Cells using Electrical Stimulation', in Proceedings - 2021 14th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics, CISP-BMEI 2021,
    Conference Papers | 2020
    Lin Q; Shivdasani MN; Tsai D; Chang YC; Jayaprakash N; Zanos S; Lovell NH; Dokos S; Guo T, 2020, 'A Computational Model of Functionally-distinct Cervical Vagus Nerve Fibers', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 2475 - 2478,
    Conference Papers | 2020
    Muralidharan M; Guo T; Shivdasani MN; Tsai D; Fried S; Cameron M; Morley JW; Dokos S; Lovell NH, 2020, 'Towards Controlling Functionally-Distinct Retinal Ganglion Cells in Degenerate Retina', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 3598 - 3601,
    Conference Papers | 2019
    Wang N; Song X; Li T; Guo T; Li L, 2019, 'A preliminary study on virtual electrode for subretinal prostheses by computational model', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), GERMANY, Berlin, pp. 5264 - 5267, presented at 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), GERMANY, Berlin, 23 July 2019 - 27 July 2019,
    Conference Papers | 2018
    Guo T; Tsai ; Muralidharan ; Suaning ; Morley ; Dokos ; Lovell , 2018, 'Computational models and tools for developing sophisticated stimulation strategies for retinal neuroprostheses', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), Honolulu, US, pp. 2248 - 2251, presented at Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE., Honolulu, US, 18 July 2018 - 22 July 2018,
    Conference Papers | 2018
    Xie HB; Guo T, 2018, 'Fuzzy Entropy Spectrum Analysis for Biomedical Signals De-Noising', in 2018 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2018, Institute of Electrical and Electronics Engineers (IEEE), Las Vegas, USA, pp. 50 - 53, presented at 2018 IEEE International Conference on Biomedical and Health Informatics, Las Vegas, USA, 04 March 2018 - 07 March 2018,
    Conference Papers | 2017
    Alqahtani A; Abed AA; Guo T; Lovell NH; Dokos S; Al Abed A, 2017, 'A continuum model of electrical stimulation of multi-compartmental retinal ganglion cells', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), Seogwipo, South Korea, pp. 2716 - 2719, presented at 2017 39th Annual International Conference of the IEEE, Seogwipo, South Korea, 11 July 2017 - 15 July 2017,
    Conference Papers | 2017
    Barriga-Rivera A; Guo T; Morley JW; Lovell NH; Suaning GJ, 2017, 'Retinal electrostimulation in rats: Activation thresholds from superior colliculus and visual cortex recordings', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), Seogwipo, South Korea, pp. 1166 - 1169, presented at 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Seogwipo, South Korea, 11 July 2017 - 15 July 2017,
    Conference Papers | 2017
    Guo T; Barriga-Rivera A; Suaning G; Tsai D; Morley J; Dokos S; Lovell N, 2017, 'Mimicking Natural Neural Encoding through Retinal Electrostimulation', Shanghai, presented at 2017 Annual International Conference of the IEEE on Neural Engineering, Shanghai, 25 May 2017 - 28 May 2017
    Conference Papers | 2016
    Yang C; Tsai D; Guo T; Suaning G; Dokos S; Morley J; Lovell N, 2016, 'High Frequency Electrical Stimulation: the Effect of Spatial Location on Retinal Ganglion Cell Responses In vitro', in Proceedings of the 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Florida USA, presented at Engineering in Medicine and Biology Society (EMBC), 2016 Annual International Conference of the IEEE., Florida USA, 16 August 2016 - 20 August 2016,
    Conference Papers | 2015
    Bai S; Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2015, 'Influence of retinal ganglion cell morphology on neuronal response properties - A simulation study', in International IEEE/EMBS Conference on Neural Engineering, NER, pp. 679 - 682,
    Conference Papers | 2015
    Guo T; Lovell NH; Tsai D; Twyford P; Fried S; Morley JW; Suaning GJ; Dokos S, 2015, 'Optimizing retinal ganglion cell responses to high-frequency electrical stimulation strategies for preferential neuronal excitation', in International IEEE/EMBS Conference on Neural Engineering, NER, pp. 252 - 255,
    Conference Papers | 2014
    Guo T; Lovell NH; Tsai D; Twyford P; Fried S; Morley JW; Suaning GJ; Dokos S, 2014, 'Selective activation of ON and OFF retinal ganglion cells to high-frequency electrical stimulation: a computational modeling study', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, pp. 6108 - 6111,
    Conference Papers | 2014
    Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2014, 'The Unique Characteristics of ON and OFF Retinal Ganglion Cells: A Modeling Study', in 2014 36TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), IEEE, Chicago, IL, pp. 6072 - 6075, presented at 36th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC), Chicago, IL, 26 August 2014 - 30 August 2014,
    Conference Papers | 2013
    Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2013, 'Cell-specific modeling of retinal ganglion cell electrical activity', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 6539 - 6542,
    Conference Papers | 2013
    Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2013, 'Influence of cell morphology in a computational model of ON and OFF retinal ganglion cells', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, pp. 4553 - 4556,
    Conference Papers | 2013
    Guo T; Tsai D; Sovilj S; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2013, 'Influence of active dendrites on firing patterns in a retinal ganglion cell model', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 4557 - 4560,
    Conference Papers | 2012
    Bradd A; Al Abed A; Guo T; Lovell NH; Dokos S, 2012, 'Study of cardiac pacemaker excitation using generic ionic models and realistic cell distribution', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., Piscataway, USA, pp. 195 - 198, presented at 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012, San Diego, CA, 28 August 2012 - 01 September 2012,
    Conference Papers | 2012
    Guo T; Tsai D; Suaning GJ; Lovell NH; Dokos S, 2012, 'Modeling normal and rebound excitation in mammalian retinal ganglion cells.', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 5506 - 5509
    Conference Papers | 2011
    Al Abed A; Guo T; Lovell NH; Dokos S, 2011, 'Tissue-based optimization of a sino-atrial node disc model', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, IEEE, Piscataway, NJ, United States, pp. 1375 - 1378, presented at 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, Massachusetts USA, 30 August 2011 - 03 September 2011,
    Conference Papers | 2011
    Guo T; Al Abed A; Lovell NH; Dokos S, 2011, 'Parameter fitting using multiple datasets in cardiac action potential modeling', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, IEEE, Piscataway, NJ, United States, pp. 158 - 161, presented at 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, Massachusetts USA, 30 August 2011 - 03 September 2011,