Dr Tom Peat

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Dr Tom Peat received a BA in biophysics and biochemistry from the University of California at Berkeley, and obtained Masters and PhD degrees from Columbia University. Tom has been involved with early-stage biotech companies in the US and has founded two companies in Australia. He has contributed over 300 structures to the Protein Data Bank and has been actively involved in fragment screening and other tools for structure-based drug development. Two of the projects he has been involved with have progressed into phase 2 clinical trials for cancer treatments.

E-mail

t.peat@unsw.edu.au

Book Chapters | 2015

Fazio VJ; Peat TS; Newman J, 2015, 'Crystallization: Digging into the past to learn lessons for the future', in , pp. 141 - 159,

Book Chapters | 2012

Hill RJ; Graham LD; Turner KA; Howell L; Tohidi-Esfahani D; Fernley R; Grusovin J; Ren B; Pilling P; Lu L; Phan T; Lovrecz GO; Pollard M; Pawlak-Skrzecz A; Streltsov VA; Peat TS; Winkler DA; Lawrence MC, 2012, 'Chapter Four Structure and Function of Ecdysone Receptors—Interactions with Ecdysteroids and Synthetic Agonists', in Insect Growth Disruptors, Elsevier, pp. 299 - 351,

Book Chapters | 2012

Hill RJ; Graham LD; Turner KA; Howell L; Tohidi-Esfahani D; Fernley R; Grusovin J; Ren B; Pilling P; Lu L; Phan T; Lovrecz GO; Pollard M; Pawlak-Skrzecz A; Streltsov VA; Peat TS; Winkler DA; Lawrence MC, 2012, 'Structure and Function of Ecdysone Receptors-Interactions with Ecdysteroids and Synthetic Agonists', in Advances in Insect Physiology, pp. 299 - 351,
Journal articles | 2024

Eldehna WM; Fares M; Bonardi A; Avgenikos M; Baselious F; Schmidt M; Al-Warhi T; Abdel-Aziz HA; Rennert R; Peat TS; Supuran CT; Wessjohann LA; Ibrahim HS, 2024, '4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells', Journal of Medicinal Chemistry, 67, pp. 20438 - 20454,

Journal articles | 2024

Esquirol L; Newman J; Nebl T; Scott C; Vickers C; Sainsbury F; Peat TS, 2024, 'Characterization of novel mevalonate kinases from the tardigrade Ramazzottius varieornatus and the psychrophilic archaeon Methanococcoides burtonii', Acta Crystallographica Section D: Structural Biology, 80, pp. 203 - 215,

Journal articles | 2024

Fulford TS; Soliman C; Castle RG; Rigau M; Ruan Z; Dolezal O; Seneviratna R; Brown HG; Hanssen E; Hammet A; Li S; Redmond SJ; Chung A; Gorman MA; Parker MW; Patel O; Peat TS; Newman J; Behren A; Gherardin NA; Godfrey DI; Uldrich AP, 2024, 'Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers', Nature Immunology, 25, pp. 1355 - 1366,

Journal articles | 2024

Joho Y; Royan S; Caputo AT; Newton S; Peat TS; Newman J; Jackson C; Ardevol A, 2024, 'Enhancing PET Degrading Enzymes: A Combinatory Approach', ChemBioChem, 25,

Journal articles | 2024

Yi X; Kleinbeck F; Ching C; Boghospor L; Gomes S; Alvizo O; Allmendinger T; Fell J; Subramanian N; Li M; Garcia R; Riggins J; Entwistle D; Richter Y; Gschwend D; Lauener L; Peat TS; Lebhar H; Schlama T; Ruch T, 2024, 'Enhancing the Imine Reductase Activity of a Promiscuous Glucose Dehydrogenase for Scalable Manufacturing of a Chiral Neprilysin Inhibitor Precursor', ACS Catalysis, 14, pp. 7087 - 7096,

Journal articles | 2023

Sharma S; Chung CY; Uryu S; Petrovic J; Cao J; Rickard A; Nady N; Greasley S; Johnson E; Brodsky O; Khan S; Wang H; Wang Z; Zhang Y; Tsaparikos K; Chen L; Mazurek A; Lapek J; Kung PP; Sutton S; Richardson PF; Greenwald EC; Yamazaki S; Jones R; Maegley KA; Bingham P; Lam H; Stupple AE; Kamal A; Chueh A; Cuzzupe A; Morrow BJ; Ren B; Carrasco-Pozo C; Tan CW; Bhuva DD; Allan E; Surgenor E; Vaillant F; Pehlivanoglu H; Falk H; Whittle JR; Newman J; Cursons J; Doherty JP; White KL; MacPherson L; Devlin M; Dennis ML; Hattarki MK; De Silva M; Camerino MA; Butler MS; Dolezal O; Pilling P; Foitzik R; Stupple PA; Lagiakos HR; Walker SR; Hediyeh-Zadeh S; Nuttall S; Spall SK; Charman SA; Connor T; Peat TS; Avery VM; Bozikis YE; Yang Y; Zhang M; Monahan BJ; Voss AK; Thomas T; Street IP; Dawson SJ; Dawson MA; Lindeman GJ; Davis MJ; Visvader JE; Paul TA, 2023, 'Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer', Cell Chemical Biology, 30, pp. 1191 - 1210.e20,

Journal articles | 2022

Ahmed FH; Caputo AT; French NG; Peat TS; Whitfield J; Warden AC; Newman J; Scott1 C, 2022, 'Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed', Acta Crystallographica Section D: Structural Biology, 78, pp. 599 - 612,

Journal articles | 2022

Satta A; Esquirol L; Ebert BE; Newman J; Peat TS; Plan M; Schenk G; Vickers CE, 2022, 'Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase', FEBS Journal, 289, pp. 6672 - 6693,

Journal articles | 2021

Caputo AT; Eder OM; Bereznakova H; Pothuis H; Ardevol A; Newman J; Nuttall S; Peat TS; Adams TE, 2021, 'Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins', Scientific Reports, 11,

Journal articles | 2021

Gumus A; Bozdag M; Angeli A; Peat TS; Carta F; Supuran CT; Selleri S, 2021, 'Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors', Bioorganic and Medicinal Chemistry Letters, 49,

Journal articles | 2021

Guo Z; Smutok O; Johnston WA; Walden P; Ungerer JPJ; Peat TS; Newman J; Parker J; Nebl T; Hepburn C; Melman A; Suderman RJ; Katz E; Alexandrov K, 2021, 'Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices', Nature Communications, 12,

Journal articles | 2021

Mueller SL; Chrysanthopoulos PK; Halili MA; Hepburn C; Nebl T; Supuran CT; Nocentini A; Peat TS; Poulsen SA, 2021, 'The glitazone class of drugs as carbonic anhydrase inhibitors—a spin-off discovery from fragment screening', Molecules, 26,

Journal articles | 2020

Angeli A; Peat TS; Selleri S; Saleh Alfawaz Altamimi A; Supuran CT; Carta F, 2020, 'X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX', Bioorganic Chemistry, 97,

Journal articles | 2020

Berrino E; Angeli A; Zhdanov DD; Kiryukhina AP; Milaneschi A; De Luca A; Bozdag M; Carradori S; Selleri S; Bartolucci G; Peat TS; Ferraroni M; Supuran CT; Carta F, 2020, 'Azidothymidine "clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors', Journal of Medicinal Chemistry, 63, pp. 7392 - 7409,

Journal articles | 2020

Dennis ML; Newman J; Dolezal O; Hattarki M; Surjadi RN; Nuttall SD; Pham T; Nebl T; Camerino M; Khoo PS; Monahan BJ; Peat TS, 2020, 'Crystal structures of human ENPP1 in apo and bound forms', Acta Crystallographica Section D: Structural Biology, 76, pp. 889 - 898,

Journal articles | 2020

Esquirol L; Peat TS; Sugrue E; Balotra S; Rottet S; Warden AC; Wilding M; Hartley CJ; Jackson CJ; Newman J; Scott C, 2020, 'Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application', Advances in Microbial Physiology, 76, pp. 129 - 186,

Journal articles | 2020

Fares M; Eldehna WM; Bua S; Lanzi C; Lucarini L; Masini E; Peat TS; Abdel-Aziz HA; Nocentini A; Keller PA; Supuran CT, 2020, 'Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action', Journal of Medicinal Chemistry, 63, pp. 3317 - 3326,

Journal articles | 2020

MacPherson L; Anokye J; Yeung MM; Lam EYN; Chan YC; Weng CF; Yeh P; Knezevic K; Butler MS; Hoegl A; Chan KL; Burr ML; Gearing LJ; Willson T; Liu J; Choi J; Yang Y; Bilardi RA; Falk H; Nguyen N; Stupple PA; Peat TS; Zhang M; de Silva M; Carrasco-Pozo C; Avery VM; Khoo PS; Dolezal O; Dennis ML; Nuttall S; Surjadi R; Newman J; Ren B; Leaver DJ; Sun Y; Baell JB; Dovey O; Vassiliou GS; Grebien F; Dawson SJ; Street IP; Monahan BJ; Burns CJ; Choudhary C; Blewitt ME; Voss AK; Thomas T; Dawson MA, 2020, 'HBO1 is required for the maintenance of leukaemia stem cells', Nature, 577, pp. 266 - 270,

Journal articles | 2020

Newman J; Nebl T; Van H; Peat TS, 2020, 'The X-ray crystal structure of the N-terminal domain of Ssr4, a Schizosaccharomyces pombe chromatin-remodelling protein', Acta Crystallographica Section F: Structural Biology Communications, 76, pp. 583 - 589,

Journal articles | 2019

Angeli A; Di Cesare Mannelli L; Ghelardini C; Peat TS; Bartolucci G; Menicatti M; Carta F; Supuran CT, 2019, 'Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects', European Journal of Medicinal Chemistry, 177, pp. 188 - 197,

Journal articles | 2019

Dennis ML; Esquirol L; Nebl T; Newman J; Scott C; Peat TS, 2019, 'The evolving story of AtzT, a periplasmic binding protein', Acta Crystallographica Section D: Structural Biology, 75, pp. 995 - 1002,

Journal articles | 2019

Dennis ML; Morrow BJ; Dolezal O; Cuzzupe AN; Stupple AE; Newman J; Bentley J; Hattarki M; Nuttall SD; Foitzik RC; Street IP; Stupple PA; Monahan BJ; Peat TS, 2019, 'Fragment screening for a protein-protein interaction inhibitor to WDR5', Structural Dynamics, 6,

Journal articles | 2019

Kaczmarski JA; Hong NS; Mukherjee B; Wey LT; Rourke L; Förster B; Peat TS; Price GD; Jackson CJ, 2019, 'Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001', Biochemistry, 58, pp. 5030 - 5039,

Journal articles | 2019

Newman J; Caron K; Nebl T; Peat TS, 2019, 'Structures of the transcriptional regulator BgaR, a lactose sensor', Acta Crystallographica Section D: Structural Biology, 75, pp. 639 - 646,

Journal articles | 2019

Tanini D; Ricci L; Capperucci A; Di Cesare Mannelli L; Ghelardini C; Peat TS; Carta F; Angeli A; Supuran CT, 2019, 'Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity', European Journal of Medicinal Chemistry, 181,

Journal articles | 2018

Angeli A; Di Cesare Mannelli L; Trallori E; Peat TS; Ghelardini C; Carta F; Supuran CT, 2018, 'Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology', ACS Medicinal Chemistry Letters, 9, pp. 462 - 467,

Journal articles | 2018

Angeli A; di Cesare Mannelli L; Lucarini E; Peat TS; Ghelardini C; Supuran CT, 2018, 'Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects', European Journal of Medicinal Chemistry, 154, pp. 210 - 219,

Journal articles | 2018

Baell JB; Leaver DJ; Hermans SJ; Kelly GL; Brennan MS; Downer NL; Nguyen N; Wichmann J; McRae HM; Yang Y; Cleary B; Lagiakos HR; Mieruszynski S; Pacini G; Vanyai HK; Bergamasco MI; May RE; Davey BK; Morgan KJ; Sealey AJ; Wang B; Zamudio N; Wilcox S; Garnham AL; Sheikh BN; Aubrey BJ; Doggett K; Chung MC; de Silva M; Bentley J; Pilling P; Hattarki M; Dolezal O; Dennis ML; Falk H; Ren B; Charman SA; White KL; Rautela J; Newbold A; Hawkins ED; Johnstone RW; Huntington ND; Peat TS; Heath JK; Strasser A; Parker MW; Smyth GK; Street IP; Monahan BJ; Voss AK; Thomas T, 2018, 'Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth', Nature, 560, pp. 253 - 257,

Journal articles | 2018

Dennis ML; Lee MD; Harjani JR; Ahmed M; DeBono AJ; Pitcher NP; Wang ZC; Chhabra S; Barlow N; Rahmani R; Cleary B; Dolezal O; Hattarki M; Aurelio L; Shonberg J; Graham B; Peat TS; Baell JB; Swarbrick JD, 2018, '8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase', Chemistry - A European Journal, 24, pp. 1922 - 1930,

Journal articles | 2018

Esquirol L; Peat TS; Wilding M; Hartley CJ; Newman J; Scott C, 2018, 'A novel decarboxylating amidohydrolase involved in avoiding metabolic dead ends during cyanuric acid catabolism in Pseudomonas sp. Strain ADP', PLoS ONE, 13,

Journal articles | 2018

Esquirol L; Peat TS; Wilding M; Liu JW; French NG; Hartley CJ; Onagi H; Nebl T; Easton CJ; Newman J; Scott C, 2018, 'An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme', Journal of Biological Chemistry, 293, pp. 7880 - 7891,

Journal articles | 2018

Esquirol L; Peat TS; Wilding M; Lucent D; French NG; Hartley CJ; Newman J; Scott C, 2018, 'Structural and biochemical characterization of the biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841', PLoS ONE, 13,

Journal articles | 2018

Liang YL; Khoshouei M; Deganutti G; Glukhova A; Koole C; Peat TS; Radjainia M; Plitzko JM; Baumeister W; Miller LJ; Hay DL; Christopoulos A; Reynolds CA; Wootten D; Sexton PM, 2018, 'Cryo-EM structure of the active, G s -protein complexed, human CGRP receptor', Nature, 561, pp. 492 - 497,

Journal articles | 2018

Mujumdar P; Bua S; Supuran CT; Peat TS; Poulsen SA, 2018, 'Synthesis, structure and bioactivity of primary sulfamate-containing natural products', Bioorganic and Medicinal Chemistry Letters, 28, pp. 3009 - 3013,

Journal articles | 2018

Newman J; Sharp JA; Enjapoori AK; Bentley J; Nicholas KR; Adams TE; Peat TS, 2018, 'Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus', Acta Crystallographica Section F: Structural Biology Communications, 74, pp. 39 - 45,

Journal articles | 2017

Angeli A; Tanini D; Peat TS; Di Cesare Mannelli L; Bartolucci G; Capperucci A; Ghelardini C; Supuran CT; Carta F, 2017, 'Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors', ACS Medicinal Chemistry Letters, 8, pp. 963 - 968,

Journal articles | 2017

Chrysanthopoulos PK; Mujumdar P; Woods LA; Dolezal O; Ren B; Peat TS; Poulsen SA, 2017, 'Identification of a New Zinc Binding Chemotype by Fragment Screening', Journal of Medicinal Chemistry, 60, pp. 7333 - 7349,

Journal articles | 2017

Davies C; Böttcher C; Boss PK; Peat T; Newman J, 2017, 'Understanding the control of grape berry ripening and developing opportunities for its manipulation', Acta Horticulturae, 1157, pp. 1 - 10,

Journal articles | 2017

Fisher CR; Sutton HJ; Kaczmarski JA; McNamara HA; Clifton B; Mitchell J; Cai Y; Dups JN; D'Arcy NJ; Singh M; Chuah A; Peat TS; Jackson CJ; Cockburn IA, 2017, 'T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein', PLoS Pathogens, 13,

Journal articles | 2017

Peat TS; Balotra S; Wilding M; Hartley CJ; Newman J; Scott C, 2017, 'High-resolution X-ray structures of two functionally distinct members of the cyclic amide hydrolase family of Toblerone fold enzymes', Applied and Environmental Microbiology, 83,

Journal articles | 2017

Wilding M; Peat TS; Kalyaanamoorthy S; Newman J; Scott C; Jermiin LS, 2017, 'Reverse engineering: Transaminase biocatalyst development using ancestral sequence reconstruction', Green Chemistry, 19, pp. 5375 - 5380,

Journal articles | 2017

Wilding M; Scott C; Newman J; Peat TS, 2017, 'Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC', Acta Crystallographica Section:F Structural Biology Communications, 73, pp. 29 - 35,

Journal articles | 2017

Wilding M; Scott C; Peat TS; Newman J, 2017, 'X-ray crystal structure of a malonate-semialdehyde dehydrogenase from Pseudomonas sp. strain AAC', Acta Crystallographica Section:F Structural Biology Communications, 73, pp. 24 - 28,

Journal articles | 2017

Zabara A; Meikle TG; Newman J; Peat TS; Conn CE; Drummond CJ, 2017, 'The nanoscience behind the art of: In-meso crystallization of membrane proteins', Nanoscale, 9, pp. 754 - 763,

Journal articles | 2017

Zabara A; Meikle TG; Trenker R; Yao S; Newman J; Peat TS; Separovic F; Conn CE; Call MJ; Call ME; Landau EM; Drummond CJ, 2017, 'Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay between Lipid Molecular Structure, Mesophase Structure and Properties, and Crystallogenesis', Crystal Growth and Design, 17, pp. 5667 - 5674,

Journal articles | 2016

Angeli A; Peat TS; Bartolucci G; Nocentini A; Supuran CT; Carta F, 2016, 'Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors', Organic and Biomolecular Chemistry, 14, pp. 11353 - 11356,

Journal articles | 2016

Brewster JL; McKellar JLO; Finn TJ; Newman J; Peat TS; Gerth ML, 2016, 'Structural basis for ligand recognition by a Cache chemosensory domain that mediates carboxylate sensing in Pseudomonas syringae', Scientific Reports, 6,

Journal articles | 2016

Dennis ML; Pitcher NP; Lee MD; Debono AJ; Wang ZC; Harjani JR; Rahmani R; Cleary B; Peat TS; Baell JB; Swarbrick JD, 2016, 'Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli', Journal of Medicinal Chemistry, 59, pp. 5248 - 5263,

Journal articles | 2016

Kryshtafovych A; Moult J; Baslé A; Burgin A; Craig TK; Edwards RA; Fass D; Hartmann MD; Korycinski M; Lewis RJ; Lorimer D; Lupas AN; Newman J; Peat TS; Piepenbrink KH; Prahlad J; van Raaij MJ; Rohwer F; Segall AM; Seguritan V; Sundberg EJ; Singh AK; Wilson MA; Schwede T, 2016, 'Some of the most interesting CASP11 targets through the eyes of their authors', Proteins: Structure, Function and Bioinformatics, 84, pp. 34 - 50,

Journal articles | 2016

Mujumdar P; Teruya K; Tonissen KF; Vullo D; Supuran CT; Peat TS; Poulsen SA, 2016, 'An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C', Journal of Medicinal Chemistry, 59, pp. 5462 - 5470,

Journal articles | 2016

Wilding M; Peat TS; Newman J; Scott C, 2016, 'A β-alanine catabolism pathway containing a highly promiscuous ω-transaminase in the 12-aminododecanate-degrading Pseudomonas sp. strain AAC', Applied and Environmental Microbiology, 82, pp. 3846 - 3856,

Journal articles | 2016

Woods LA; Dolezal O; Ren B; Ryan JH; Peat TS; Poulsen SA, 2016, 'Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination', Journal of Medicinal Chemistry, 59, pp. 2192 - 2204,

Journal articles | 2015

Balotra S; Newman J; Cowieson NP; French NG; Campbell PM; Briggs LJ; Warden AC; Easton CJ; Peat TS; Scott C, 2015, 'X-Ray structure of the amidase domain of AtzF, the allophanate hydrolase from the cyanuric acid-mineralizing multienzyme complex', Applied and Environmental Microbiology, 81, pp. 470 - 480,

Journal articles | 2015

Balotra S; Warden AC; Newman J; Briggs LJ; Scott C; Peat TS, 2015, 'X-Ray structure and mutagenesis studies of the n-isopropylammelide isopropylaminohydrolase, AtzC', PLoS ONE, 10,

Journal articles | 2015

Basnet SKC; Diab S; Schmid R; Yu M; Yang Y; Gillam TA; Teo T; Li P; Peat T; Albrecht H; Wang S, 2015, 'Identification of a highly conserved allosteric binding site on Mnk1 and Mnk2 s', Molecular Pharmacology, 88, pp. 935 - 948,

Journal articles | 2015

Peat TS; Newman J; Balotra S; Lucent D; Warden AC; Scott C, 2015, 'The structure of the hexameric atrazine chlorohydrolase AtzA', Acta Crystallographica Section D: Biological Crystallography, 71, pp. 710 - 720,

Journal articles | 2015

Ryan JH; Jarvis KE; Mulder RJ; Francis CL; Savage GP; Dolezal O; Peat TS; Deadman JJ, 2015, 'Unexpected Isomerisation of a Fragment Analogue During Fragment-Based Screening of HIV Integrase Catalytic Core Domain', Australian Journal of Chemistry, 68, pp. 1871 - 1879,

Journal articles | 2015

Suryadinata R; Seabrook SA; Adams TE; Nuttall SD; Peat TS, 2015, 'Structural and biochemical analyses of a Clostridium perfringens sortase D transpeptidase', Acta Crystallographica Section D: Biological Crystallography, 71, pp. 1505 - 1513,

Journal articles | 2015

Tanpure RP; Ren B; Peat TS; Bornaghi LF; Vullo D; Supuran CT; Poulsen SA, 2015, 'Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site', Journal of Medicinal Chemistry, 58, pp. 1494 - 1501,

Journal articles | 2015

Warden AC; Williams M; Peat TS; Seabrook SA; Newman J; Dojchinov G; Haritos VS, 2015, 'Rational engineering of a mesohalophilic carbonic anhydrase to an extreme halotolerant biocatalyst', Nature Communications, 6,

Journal articles | 2014

Balotra S; Newman J; French NG; Briggs LJ; Peat TS; Scott C, 2014, 'Crystallization and preliminary X-ray diffraction analysis of the amidase domain of allophanate hydrolase from Pseudomonas sp. strain ADP', Acta Crystallographica Section F:Structural Biology Communications, 70, pp. 310 - 315,

Journal articles | 2014

Boersma YL; Newman J; Adams TE; Cowieson N; Krippner G; Bozaoglu K; Peat TS, 2014, 'The structure of vanin 1: A key enzyme linking metabolic disease and inflammation', Acta Crystallographica Section D: Biological Crystallography, 70, pp. 3320 - 3329,

Journal articles | 2014

Dennis ML; Chhabra S; Wang ZC; Debono A; Dolezal O; Newman J; Pitcher NP; Rahmani R; Cleary B; Barlow N; Hattarki M; Graham B; Peat TS; Baell JB; Swarbrick JD, 2014, 'Structure-based design and development of functionalized mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from staphylococcus aureus', Journal of Medicinal Chemistry, 57, pp. 9612 - 9626,

Journal articles | 2014

Fazio VJ; Peat TS; Newman J, 2014, 'A drunken search in crystallization space', Acta Crystallographica Section F: Structural Biology Communications, 70, pp. 1303 - 1311,

Journal articles | 2014

Jackson CJ; Coppin CW; Carr PD; Aleksandrov A; Wilding M; Sugrue E; Ubels J; Paks M; Newman J; Peat TS; Russell RJ; Field M; Weik M; Oakeshott JG; Scott C, 2014, '300-fold increase in production of the Zn²⁺-dependent dechlorinase trzN in soluble form via apoenzyme stabilization', Applied and Environmental Microbiology, 80, pp. 4003 - 4011,

Journal articles | 2014

Kenny PW; Newman J; Peat TS, 2014, 'Nitrate in the active site of protein tyrosine phosphatase 1B is a putative mimetic of the transition state', Acta Crystallographica Section D: Biological Crystallography, 70, pp. 565 - 571,

Journal articles | 2014

Moeker J; Peat TS; Bornaghi LF; Vullo D; Supuran CT; Poulsen SA, 2014, 'Cyclic secondary sulfonamides: Unusually good inhibitors of cancer-related carbonic anhydrase enzymes', Journal of Medicinal Chemistry, 57, pp. 3522 - 3531,

Journal articles | 2014

Newman J; Peat TS; Paul Savage G, 2014, 'What's in a name? Moving towards a limited vocabulary for macromolecular crystallisation', Australian Journal of Chemistry, 67, pp. 1813 - 1817,

Journal articles | 2014

Peat TS; Dolezal O; Newman J; Mobley D; Deadman JJ, 2014, 'Interrogating HIV integrase for compounds that bind - A SAMPL challenge', Journal of Computer-Aided Molecular Design, 28, pp. 347 - 362,

Journal articles | 2014

Ren B; Peat TS; Streltsov VA; Pollard M; Fernley R; Grusovin J; Seabrook S; Pilling P; Phan T; Lu L; Lovrecz GO; Graham LD; Hill RJ, 2014, 'Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits', Acta Crystallographica Section D: Biological Crystallography, 70, pp. 1954 - 1964,

Journal articles | 2013

Chhabra S; Barlow N; Dolezal O; Hattarki MK; Newman J; Peat TS; Graham B; Swarbrick JD, 2013, 'Exploring the Chemical Space around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme HPPK', PLoS ONE, 8,

Journal articles | 2013

Chhabra S; Dolezal O; Hattarki M; Peat TS; Simpson JS; Swarbrick JD, 2013, 'Fragment screening on Staphylococcus aureus HPPK - A folate pathway target', Australian Journal of Chemistry, 66, pp. 1537 - 1543,

Journal articles | 2013

Dolezal O; Doughty L; Hattarki MK; Fazio VJ; Caradoc-Davies TT; Newman J; Peat TS, 2013, 'Fragment screening for the modelling community: SPR, ITC, and crystallography', Australian Journal of Chemistry, 66, pp. 1507 - 1517,

Journal articles | 2013

Francis CL; Kenny PW; Dolezal O; Saubern S; Kruger M; Savage GP; Peat TS; Ryan JH, 2013, 'Construction of the CSIRO fragment library', Australian Journal of Chemistry, 66, pp. 1473 - 1482,

Journal articles | 2013

Newman J; Burton DR; Caria S; Desbois S; Gee CL; Fazio VJ; Kvansakul M; Marshall B; Mills G; Richter V; Seabrook SA; Wu M; Peat TS, 2013, 'Crystallization reports are the backbone of Acta Cryst. F, but do they have any spine?', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69, pp. 712 - 718,

Journal articles | 2013

Newman J; Seabrook S; Surjadi R; Williams CC; Lucent D; Wilding M; Scott C; Peat TS, 2013, 'Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (AstC) from Escherichia coli', PLoS ONE, 8,

Journal articles | 2013

Peat TS; Balotra S; Wilding M; French NG; Briggs LJ; Panjikar S; Cowieson N; Newman J; Scott C, 2013, 'Cyanuric acid hydrolase: Evolutionary innovation by structural concatenation', Molecular Microbiology, 88, pp. 1149 - 1163,

Journal articles | 2013

Peat TS; Rhodes DI; Vandegraaff N; Le G; Smith JA; Clark LJ; Jones ED; Coates JAV; Thienthong N; Newman J; Dolezal O; Mulder R; Ryan JH; Paul Savage G; Francis CL; Deadman JJ, 2013, 'Correction: Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design (PLoS ONE)', PLoS ONE, 8,

Journal articles | 2013

Ren B; Pham TM; Surjadi R; Robinson CP; Le TK; Scott Chandry P; Peat TS; McKinstry WJ, 2013, 'Expression, purification, crystallization and preliminary X-ray diffraction analysis of a lactococcal bacteriophage small terminase subunit', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69, pp. 275 - 279,

Journal articles | 2013

Wielens J; Headey SJ; Rhodes DI; Mulder RJ; Dolezal O; Deadman JJ; Newman J; Chalmers DK; Parker MW; Peat TS; Scanlon MJ, 2013, 'Parallel screening of low molecular weight fragment libraries: Do differences in methodology affect hit identification?', Journal of Biomolecular Screening, 18, pp. 147 - 159,

Journal articles | 2013

Zhang L; Holmes IP; Hochgräfe F; Walker SR; Ali NA; Humphrey ES; Wu J; De Silva M; Kersten WJA; Connor T; Falk H; Allan L; Street IP; Bentley JD; Pilling PA; Monahan BJ; Peat TS; Daly RJ, 2013, 'Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling', Journal of Proteome Research, 12, pp. 3104 - 3116,

Journal articles | 2012

Chhabra S; Dolezal O; Collins BM; Newman J; Simpson JS; Macreadie IG; Fernley R; Peat TS; Swarbrick JD, 2012, 'Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor', PLoS ONE, 7,

Journal articles | 2012

Newman J; Bolton EE; Müller-Dieckmann J; Fazio VJ; Gallagher DT; Lovell D; Luft JR; Peat TS; Ratcliffe D; Sayle RA; Snell EH; Taylor K; Vallotton P; Velanker S; Von Delft F, 2012, 'On the need for an international effort to capture, share and use crystallization screening data', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 68, pp. 253 - 258,

Journal articles | 2012

Newman J; Dolezal O; Fazio V; Caradoc-Davies T; Peat TS, 2012, 'The DINGO dataset: A comprehensive set of data for the SAMPL challenge', Journal of Computer-Aided Molecular Design, 26, pp. 497 - 503,

Journal articles | 2012

Peat TS; Böttcher C; Newman J; Lucent D; Cowieson N; Davies C, 2012, 'Crystal structure of an indole-3-acetic acid amido synthetase from grapevine involved in auxin homeostasis', Plant Cell, 24, pp. 4525 - 4538,

Journal articles | 2012

Peat TS; Rhodes DI; Vandegraaff N; Le G; Smith JA; Clark LJ; Jones ED; Coates JAV; Thienthong N; Newman J; Dolezal O; Mulder R; Ryan JH; Savage GP; Francis CL; Deadman JJ, 2012, 'Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design', PLoS ONE, 7,

Journal articles | 2011

Falk H; Connor T; Yang H; Loft KJ; Alcindor JL; Nikolakopoulos G; Surjadi RN; Bentley JD; Hattarki MK; Dolezal O; Murphy JM; Monahan BJ; Peat TS; Thomas T; Baell JB; Parisot JP; Street IP, 2011, 'An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets', Journal of Biomolecular Screening, 16, pp. 1196 - 1205,

Journal articles | 2011

Kennedy DF; Drummond CJ; Peat TS; Newman J, 2011, 'Evaluating protic ionic liquids as protein crystallization additives', Crystal Growth and Design, 11, pp. 1777 - 1785,

Journal articles | 2011

Newman J; Pearce L; Lesburg CA; Strickland C; Peat TS, 2011, 'Crystallization of an apo form of human arginase: Using all the tools in the toolbox simultaneously', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 67, pp. 90 - 93,

Journal articles | 2011

Rhodes DI; Peat TS; Vandegraaff N; Jeevarajah D; Le G; Jones ED; Smith JA; Coates JAV; Winfield LJ; Thienthong N; Newman J; Lucent D; Ryan JH; Savage GP; Francis CL; Deadman JJ, 2011, 'Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design', Antiviral Chemistry and Chemotherapy, 21, pp. 155 - 168,

Journal articles | 2011

Rhodes DI; Peat TS; Vandegraaff N; Jeevarajah D; Newman J; Martyn J; Coates JAV; Ede NJ; Rea P; Deadman JJ, 2011, 'Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site', ChemBioChem, 12, pp. 2311 - 2315,

Journal articles | 2011

Wu N; Courtois F; Surjadi R; Oakeshott J; Peat TS; Easton CJ; Abell C; Zhu Y, 2011, 'Enzyme synthesis and activity assay in microfluidic droplets on a chip', Engineering in Life Sciences, 11, pp. 157 - 164,

Journal articles | 2011

Wu N; Oakeshott JG; Easton CJ; Peat TS; Surjadi R; Zhu Y, 2011, 'A double-emulsion microfluidic platform for in vitro green fluorescent protein expression', Journal of Micromechanics and Microengineering, 21,

Journal articles | 2010

Chhabra S; Newman J; Peat TS; Fernley RT; Caine J; Simpson JS; Swarbrick JD, 2010, 'Crystallization and preliminary X-ray analysis of 6 - Hydroxymethyl-7,8- dihydropterin pyrophosphokinase from Staphylococcus aureus', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66, pp. 575 - 578,

Journal articles | 2010

Dransfield DT; Cohen EH; Chang Q; Sparrow LG; Bentley JD; Dolezal O; Xiao X; Peat TS; Newman J; Pilling PA; Phan T; Priebe I; Brierley GV; Kastrapeli N; Kopacz K; Martik D; Wassaf D; Rank D; Conley G; Huang Y; Adams TE; Cosgrove L, 2010, 'A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo', Molecular Cancer Therapeutics, 9, pp. 1809 - 1819,

Journal articles | 2010

Ernberg K; McGrath AP; Peat TS; Adams TE; Xiao X; Pham T; Newman J; McDonald IA; Collyer CA; Guss JM, 2010, 'A new crystal form of human vascular adhesion protein 1', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66, pp. 1572 - 1578,

Journal articles | 2010

Newman J; Fazio VJ; Lawson B; Peat TS, 2010, 'The C6 Web Tool: A resource for the rational selection of crystallization conditions', Crystal Growth and Design, 10, pp. 2785 - 2792,

Journal articles | 2010

Oakley AJ; Barrett S; Peat TS; Newman J; Streltsov VA; Waddington L; Saito T; Tashiro M; McKimm-Breschkin JL, 2010, 'Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses', Journal of Medicinal Chemistry, 53, pp. 6421 - 6431,

Journal articles | 2010

Taylor MC; Jackson CJ; Tattersall DB; French N; Peat TS; Newman J; Briggs LJ; Lapalikar GV; Campbell PM; Scott C; Russell RJ; Oakeshott JG, 2010, 'Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation', Molecular Microbiology, 78, pp. 561 - 575,

Journal articles | 2009

Newman J; Cohen EH; Cosgrove L; Kopacz K; Dransfield DT; Adams TE; Peat TS, 2009, 'Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 65, pp. 945 - 948,

Journal articles | 2009

Newman J; Fazio VJ; Caradoc-Davies TT; Branson K; Peat TS, 2009, 'Practical aspects of the SAMPL challenge: Providing an extensive experimental data set for the modeling community', Journal of Biomolecular Screening, 14, pp. 1245 - 1250,

Journal articles | 2009

Wu N; Zhu Y; Brown S; Oakeshott J; Peat TS; Surjadi R; Easton C; Leech PW; Sexton BA, 2009, 'A PMMA microfluidic droplet platform for in vitro protein expression using crude E. coli S30 extract', Lab on a Chip, 9, pp. 3391 - 3398,

Journal articles | 2008

Newman J; Pham TM; Peat TS, 2008, 'Phoenito experiments: Combining the strengths of commercial crystallization automation', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 64, pp. 991 - 996,

Journal articles | 2005

Badger J; Sauder JM; Adams JM; Antonysamy S; Bain K; Bergseid MG; Buchanan SG; Buchanan MD; Batiyenko Y; Christopher JA; Emtage S; Eroshkina A; Feil I; Furlong EB; Gajiwala KS; Gao X; He D; Hendle J; Huber A; Hoda K; Kearins P; Kissinger C; Laubert B; Lewis HA; Lin J; Loomis K; Lorimer D; Louie G; Maletic M; Marsh CD; Miller I; Molinari J; Muller-Dieckmann HJ; Newman JM; Noland BW; Pagarigan B; Park F; Peat TS; Post KW; Radojicic S; Ramos A; Romero R; Rutter ME; Sanderson WE; Schwinn KD; Tresser J; Winhoven J; Wright TA; Wu L; Xu J; Harris TJR, 2005, 'Structural analysis of a set of proteins resulting from a bacterial genomics project', Proteins: Structure, Function and Genetics, 60, pp. 787 - 796,

Journal articles | 2005

Peat TS; Christopher JA; Newman J, 2005, 'Tapping the Protein Data Bank for crystallization information', Acta Crystallographica Section D: Biological Crystallography, 61, pp. 1662 - 1669,

Journal articles | 2004

Park F; Gajiwala K; Eroshkina G; Furlong E; He D; Batiyenko Y; Romero R; Christopher J; Badger J; Hendle J; Lin J; Peat T; Buchanan S, 2004, 'Crystal Structure of YIGZ, a Conserved Hypothetical Protein from Escherichia coli K12 with a Novel Fold', Proteins: Structure, Function and Genetics, 55, pp. 775 - 777,

Journal articles | 2004

Park F; Gajiwala K; Noland B; Wu L; He D; Molinari J; Loomis K; Pagarigan B; Kearins P; Christopher J; Peat T; Badger J; Hendle J; Lin J; Buchanan S, 2004, 'The 1.59 Å Resolution Crystal Structure of TM0096, a Flavin Mononucleotide Binding Protein from Thermotoga maritima', Proteins: Structure, Function and Genetics, 55, pp. 772 - 774,

Journal articles | 2002

Peat T; De la Fortelle E; Culpepper J; Newman J, 2002, 'From information management to protein annotation: Preparing protein structures for drug discovery', Acta Crystallographica Section D: Biological Crystallography, 58, pp. 1968 - 1970,

Journal articles | 2001

Cort JR; Santhana Mariappan SV; Kim CY; Park MS; Peat TS; Waldo GS; Terwilliger TC; Kennedy MA, 2001, 'Solution structure of Pyrobaculum aerophilum DsrC, an archaeal homologue of the gamma subunit of dissimilatory sulfite reductase', European Journal of Biochemistry, 268, pp. 5842 - 5850,

Journal articles | 2001

Lewis HA; Furlong EB; Laubert B; Eroshkina GA; Batiyenko Y; Adams JM; Bergseid MG; Marsh CD; Peat TS; Sanderson WE; Sauder JM; Buchanan SG, 2001, 'A structural genomics approach to the study of quorum sensing: Crystal structures of three LuxS orthologs', Structure, 9, pp. 527 - 537,

Journal articles | 2000

Peat TS; Newman JM, 2000, 'Structural genomics in the post-genomics era: The shapes of things to come', Current Opinion in Drug Discovery and Development, 3, pp. 399 - 407

Journal articles | 1999

McDonald JP; Peat TS; Levine AS; Woodgate R, 1999, 'Intermolecular cleavage by UmuD-like enzymes: Identification of residues required for cleavage and substrate specificity', Journal of Molecular Biology, 285, pp. 2199 - 2209,

Journal articles | 1999

Newman J; Peat TS; Richard R; Kan L; Swanson PE; Affholter JA; Holmes IH; Schindler JF; Unkefer CJ; Terwilliger TC, 1999, 'Haloalkane dehalogenases: Structure of a Rhodococcus enzyme', Biochemistry, 38, pp. 16105 - 16114,

Journal articles | 1998

McLenigan M; Peat TS; Frank EG; McDonald JP; Gonzalez M; Levine AS; Hendrickson WA; Woodgate R, 1998, 'Novel Escherichia coli umuD' mutants: Structure-function insights into SOS mutagenesis', Journal of Bacteriology, 180, pp. 4658 - 4666,

Journal articles | 1998

Peat TS; Newman J; Waldo GS; Berendzen J; Terwilliger TC, 1998, 'Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 Å resolution', Structure, 6, pp. 1207 - 1214,

Journal articles | 1998

Ruscetti T; Newman J; Peat TS; Francis J; Nolan R; Terwilliger TC; Peterson SR; Lehnert BE, 1998, 'A nondenaturing purification scheme for the DNA-binding domain of poly(ADP-ribose) polymerase, a structure-specific DNA-binding protein', Protein Expression and Purification, 14, pp. 79 - 86,

Journal articles | 1998

Terwilliger TC; Waldo G; Peat TS; Newman JM; Chu K; Berendzen J, 1998, 'Class-directed structure determination: Foundation for a protein structure initiative', Protein Science, 7, pp. 1851 - 1856,

Journal articles | 1996

Peat TS; Frank EG; McDonald JP; Levine AS; Woodgate R; Hendrickson WA, 1996, 'Structure of the UmuD′ protein and its regulation in response to DNA damage', Nature, 380, pp. 727 - 730,

Journal articles | 1996

Peat TS; Frank EG; McDonald JP; Levine AS; Woodgate R; Hendrickson WA, 1996, 'The UmuD' protein filament and its potential role in damage induced mutagenesis', Structure, 4, pp. 1401 - 1412,

Journal articles | 1996

Peat TS; Frank EG; Woodgate R; Hendrickson WA, 1996, 'Production and crystallization of a selenomethionyl variant of UmuD', an Escherichia coli SOS response protein', Proteins: Structure, Function and Genetics, 25, pp. 506 - 509, http://dx.doi.org/10.1002/(SICI)1097-0134(199608)25:4<506::AID-PROT10>3.3.CO;2-Z

Journal articles | 1995

Urs UK; Sharkey DJ; Peat TS; Hendrickson WA; Krishna Murthy HM, 1995, 'Characterization of crystals of the thermostable DNA polymerase I from thermus aquaticus', Proteins: Structure, Function, and Bioinformatics, 23, pp. 111 - 114,

Journal articles | 1981

BLITZ J; PEAT TS, 1981, 'THE APPLICATION OF MULTIFREQUENCY EDDY CURRENTS TO TESTING FERROMAGNETIC METALS', NDT INTERNATIONAL, 14, pp. 15 - 17,
Conference Papers | 2021

Sharma S; Chung J; Uryu S; Rickard A; Nady N; Khan S; Wang Z; Zhang Y; Zhang H; Kung P-P; Greenwald E; Maegley K; Bingham P; Lam H; Bozikis YE; Falk H; Allan E; Avery VM; Butler MS; Camerino MA; Carrasco-Pozo C; Charman SA; Davis MJ; Dawson MA; Sarah-Jane D; de Silva M; Dennis ML; Dolezal O; Lagiakos R; Lindeman GJ; MacPherson L; Nuttall S; Peat TS; Ren B; Stupple AE; Surgenor E; Tan CW; Thomas T; Visvader JE; Voss AK; Vaillant F; White KL; Whittle J; Yang Y; Hediyeh-Zadeh S; Stupple PA; Street IP; Monahan BJ; Paul T, 2021, 'First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER plus breast cancer with KAT6A dysregulation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH,

Preprints | 2019

Kaczmarski JA; Hong N-S; Mukherjee B; Wey LT; Rourke L; Förster B; Peat TS; Price GD; Jackson CJ, 2019, Structural basis for the allosteric regulation of the SbtA bicarbonate transporter by the P_II-like protein, SbtB, fromCyanobiumsp. PCC7001,

Conference Papers | 2018

Peat TS; Dennis M; Dolezal O; Newman J; Morrow B; Monahan B; Foitzik R; Khoo PS; Stupple P; Street I, 2018, 'Fragment screening for a protein-protein interaction inhibitor to WDR5', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. A139 - A139,

Conference Papers | 2015

Falk H; Foitzik RC; Allan E; deSilva M; Yang H; Bozikis YE; Nikac M; Walker SR; Camerino MA; Morrow BJ; Stupple AE; Lagiakos R; Pinson J-A; Lessene R; Kersten WJA; Ganame DG; Holmes IP; Lunniss GE; Chung M; Hermans SJ; Parker MW; Thistlethwaite A; White K; Charman SA; Monahan BJ; Pilling P; Grusovin J; Peat TS; Sonderegger S; Toulmin E; Jane SM; Curtis DJ; Stupple PA; Street IP, 2015, 'PRMT5 inhibitors as novel treatment for cancers', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015,

Conference Papers | 2013

Lapierre F; Best M; Stewart R; Oakeshott J; Peat T; Zhu Y, 2013, 'Integrated microdroplet-based system for enzyme synthesis and sampling', in Proceedings of SPIE - The International Society for Optical Engineering,

Conference Papers | 2013

Lapierre F; Cameron NR; Oakeshott J; Peat T; Zhu Y, 2013, 'How to fabricate robust microfluidic systems for a dollar', in Proceedings of SPIE - The International Society for Optical Engineering,

Conference Papers | 2011

Peat TS; Deadman JJ; Rhodes DI; Newman J; Dolezal O; Vandegraaff N; Smith JA; Le G; Ryan JH; Francis CL; Savage GP, 2011, 'New HIV Integrase inhibitors discovered through fragment screening', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. C291 - C291,

Conference Papers | 2005

Peat TS; Christopher J; Schmidt K, 2005, 'AFITT-Working with Good Chemistry', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. C165 - C165,

Conference Papers | 2002

Lewis HA; Furlong EB; Laubert B; Eroshkina GA; Batiyenko Y; Adams JM; Bergseid MG; Winhoven J; Marsh CD; Peat TS; Sanderson WE; Sauder JM; Buchanan SG, 2002, 'THE QUORUM SENSING PROTEIN LuxS: FUNCTIONAL INSIGHTS FROM STRUCTURE', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. C194 - C194,

Conference Papers | 1999

Peat TS; Newman J; Waldo G; Terwilliger TC, 1999, 'PROTEOMICS AND THE SHOTGUN APPROACH TO STRUCTURE.', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. 317 - 317,

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